Adcilib 125mg Capsule
Product Info
| Prescription required | Yes |
| Marketer | Adley Formulations |
| Active Ingredient | Palbociclib (125mg) |
| Storage | Store below 30°C |
| Chemical Class | Pyridinylpiperazines |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Cyclin-Dependent Kinase Inhibitor |
| User Rating | 4.2 |
| User Reviews | 752 |
FAQ
What kind of medicine is Adcilib 125mg?
Adcilib 125mg is an anti-cancer medicine. Adcilib 125mg blocks proteins known as cyclin-dependent kinase inhibitors. Blocking these proteins can slow down the growth of cancer cells and delay the progression of the cancer.
Are the side effects of Adcilib 125mg irreversible?
No, most of the side effects are reversible and disappear when the medicine is stopped. Neutropenia is a well-recognized adverse effect of Adcilib 125mg in which the number of your white blood cells get reduced and your immune system gets weakened. As a result, you may be at greater risk of getting an infection while you are taking Adcilib 125mg. However, this side effect disappears rapidly once you stop taking the medicine.
How long do I have to take Adcilib 125mg?
The duration of treatment varies from person to person. Your doctor will decide the number of cycles you need to receive based on your condition, response to treatment and your tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience certain side effects.
Do I need to use birth control method while using Adcilib 125mg?
Women of childbearing potential who are receiving Adcilib 125mg and their partners should use adequate contraceptive methods (e.g. double-barrier contraception such as condom and diaphragm). These methods should be used during therapy and for at least 3 weeks after completing therapy for females. Men who are on Adcilib 125mg therapy should use birth control methods for at least 14 weeks after completing the therapy.
How should I take Adcilib 125mg?
Generally, Adcilib 125mg is taken once daily for 21 consecutive days followed by 7 days off treatment to add up a complete cycle of 28 days. Take this medicine with food and at the same time each day. Swallow the whole capsules. Do not open, chew, or crush them. Do not take the capsules that are broken or cracked. If you vomit after taking Adcilib 125mg, do not take another dose and continue your regular dosing schedule.
Does Adcilib 125mg affect fertility?
Male fertility may be affected during treatment with Adcilib 125mg. Thus, men may consider sperm preservation prior to beginning therapy with Adcilib 125mg.
What are the serious side effects of Adcilib 125mg?
The serious side effects of Adcilib 125mg include shortness of breath, dizziness, weakness, unusual bleeding or bruising or nosebleeds. It may also cause fever, chills or signs of infection and fast, irregular or pounding heartbeat. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment.
Does treatment with Adcilib 125mg require monitoring of blood counts?
Yes, blood tests are important since this medicine can lower your blood counts. The regular blood tests check the effect of Adcilib 125mg on your blood cells (white blood cells, red blood cells, and platelets). These tests should be done at the beginning of each chemotherapy cycle, on the 15th day of the first 2 cycles, and as clinically indicated.
Adcilib 125mg Capsule Reviews
Adcilib 125mg is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Adcilib 125mg should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include fatigue, hair loss, rash, vomiting, and diarrhea. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It is better to inform your doctor if you notice symptoms of infection like fever, chills, and weakness, bleeding or bruising and nose bleed. It might also cause dizziness if it happens avoid driving or attention-seeking activities.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Adcilib 125mg should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include fatigue, hair loss, rash, vomiting, and diarrhea. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It is better to inform your doctor if you notice symptoms of infection like fever, chills, and weakness, bleeding or bruising and nose bleed. It might also cause dizziness if it happens avoid driving or attention-seeking activities.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
How Adcilib 125mg Capsule Works
Adcilib 125mg is an anti-cancer medication. Cyclin dependent kinase 4 and 6
(chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells. This medicine works by inhibiting cyclin dependent kinase 4 and 6, thus arrests the cancer cell cycle (cell growing process). It also targets the estrogen (hormone) receptor-positive breast cancer cells by disrupting the cell cycle.
How to Use Adcilib 125mg Capsule
Take this medicine in the dose and duration as advised by your doctor. Adcilib 125mg is to be taken with food.
Benefits of Adcilib 125mg Capsule
- In Breast cancer: Adcilib 125mg helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Adcilib 125mg kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
Uses of Adcilib 125mg Capsule
- Breast cancer
Adcilib 125mg Capsule Side Effects
Safety Tips
Breast feeding
UNSAFE
Adcilib 125mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy
CONSULT YOUR DOCTOR
Adcilib 125mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Adcilib 125mg. Please consult your doctor.
Liver
CAUTION
Adcilib 125mg should be used with caution in patients with liver disease. Dose adjustment of Adcilib 125mg may be needed. Please consult your doctor.
Driving
UNSAFE
Adcilib 125mg may cause side effects which could affect your ability to drive.It may cause fatigue in some people. If this happens, you should exercise caution when driving or using machines.
Kidney
SAFE IF PRESCRIBED
Adcilib 125mg is safe to use in patients with kidney disease. No dose adjustment of Adcilib 125mg is recommended.
Quick Tips
- Use effective contraception method to prevent pregnancy while taking this medicine.
- If you forget to take the medicine or vomit, skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose
- It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you.
- You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness.
- Take it with food, preferably at the same time every day.
- Do not stop taking the medication without talking to your doctor first.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
References
- Central Drugs Standard Control Organisation (CDSCO).
- Palbociclib. New York, New York: Pfizer Labs; 2015 [revised 31 Mar. 2017].