Afogatran 150 Capsule
Product Info
| Prescription required | Yes |
| Marketer | Torrent Pharmaceuticals Ltd |
| Active Ingredient | Dabigatran Etexilate (150mg) |
| Storage | Store below 30°C |
| Chemical Class | Benzimidazole derivative |
| Habit Forming | No |
| Therapeutic Class | CARDIAC |
| Action Class | Direct thrombin inhibitor- oral |
| User Rating | 4.2 |
| User Reviews | 379 |
FAQ
When will I feel better after taking Afogatran 150?
Afogatran 150 reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Afogatran 150. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
How should I store Afogatran 150?
Afogatran 150 should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Store the medicine at a dry place and protect the capsules from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once the bottle is opened, it should be used within 4 months. If unused within 4 months, please discard them safely.
Who should not take Afogatran 150?
People experiencing any unusual bleeding or people allergic to Afogatran 150 should not take it. Afogatran 150 should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced.
When should I take Afogatran 150?
Mostly, Afogatran 150 is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours.
Does Afogatran 150 affect the liver?
Unlike other anticoagulants, Afogatran 150 usually does not affect the functioning of the liver. But long-term use of Afogatran 150 may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.
Can I drink alcohol with Afogatran 150?
Taking alcohol while taking Afogatran 150 can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.
Can Afogatran 150 cause hair loss?
As compared to other blood-thinning medications, Afogatran 150 does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Afogatran 150. Consult your doctor if you face hair loss while taking Afogatran 150 to rule out any other causes of hair loss.
Can the use of Afogatran 150 increase the risk of bleeding?
Yes, Afogatran 150 increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
What if you forget to take Afogatran Capsule?
If you missed a dose of Afogatran 150, take it as soon as possible on the same day. The missed dose should be skipped if it cannot be taken at least 6 hours before the next scheduled dose. Do not double the dose to make up for a missed dose.
Afogatran 150 Capsule Reviews
Afogatran 150 is an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart.
Afogatran 150 is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.
The most common side effect of Afogatran 150 are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headaches, seizures, allergic reactions, changes to your eyesight, and tiredness.
Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.
Afogatran 150 is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.
The most common side effect of Afogatran 150 are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headaches, seizures, allergic reactions, changes to your eyesight, and tiredness.
Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.
How Afogatran 150 Capsule Works
Afogatran 150 is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.
How to Use Afogatran 150 Capsule
Take this medicine in the dose and duration as advised by your doctor. Afogatran 150 may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Afogatran 150 Capsule
- In Treatment and prevention of Blood clots: Afogatran 150 is a type of medicine known as an anticoagulant. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It will also prevent new ones from forming. It works by blocking a substance in the body which is involved in blood clotting. This keeps your blood flowing freely around your body and makes it less likely that a clot will form inside a blood vessel. This can help prevent or reduce damage caused by stroke, clots in your lungs (pulmonary embolism), or other blood vessels (thrombosis). It can also make it less likely that parts of a clot will break off and travel to other parts of the body. You should take it regularly and make appropriate lifestyle changes to help this medicine be effective.
Uses of Afogatran 150 Capsule
- Treatment and prevention of Blood clots
Afogatran 150 Capsule Side Effects
Safety Tips
Breast feeding
CONSULT YOUR DOCTOR
Afogatran 150 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Liver
CAUTION
Afogatran 150 should be used with caution in patients with liver disease. Dose adjustment of Afogatran 150 may be needed. Please consult your doctor.
Alcohol
UNSAFE
It is unsafe to consume alcohol with Afogatran 150.
Kidney
CAUTION
Afogatran 150 should be used with caution in patients with severe kidney disease. Dose adjustment of Afogatran 150 may be needed. Please consult your doctor.Use of Afogatran 150 is not recommended in patients with severe kidney disease.
Driving
SAFE
Afogatran 150 does not usually affect your ability to drive.
Pregnancy
CONSULT YOUR DOCTOR
Afogatran 150 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Quick Tips
- Do not stop taking the medication without talking to your doctor.
- Take it as per dose and duration suggested by your doctor.
- Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
- Afogatran 150 increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling).
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- If you are going to have a surgery or dental treatment, you may be asked to stop taking Afogatran 150 temporarily.
References
- Dabigatran Etexilate [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021.
- Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-66.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
- Central Drugs Standard Control Organisation (CDSCO). Dabigatran Etexilate.
- Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 363-65.
- Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 594.
- Dabigatran etexilate mesylate. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2010 [revised Nov. 2015].
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dabigatran. [Updated 2020 Jan 20].