Amantrel Capsule


Product Info

Prescription required Yes
Marketer Cipla Ltd
Active Ingredient Amantadine (100mg)
Storage Store below 30°C
Chemical ClassSynthetic Tricyclic Amine Derivative
Habit FormingNo
Therapeutic ClassNEURO CNS
Action ClassDopamine facilitator
User Rating4.4
User Reviews615

FAQ

Question
Is Amantrel a dopamine agonist?
Yes, Amantrel is a dopamine agonist. Dopamine is needed to control movements in the brain. Amantrel works by increasing the amount of dopamine, thereby helping in controlling the movements in Parkinson’s disease.
Answer

Question
What happens when I stop taking Amantrel?
Do not stop taking this medicine or lower the dose without first checking with your doctor. If required, your doctor will gradually reduce the amount you take each day before stopping it completely. Abruptly stopping Amantrel may result in worsening of Parkinsonism. It may also cause delirium, agitation, delusions, hallucinations, paranoid reaction, stupor, anxiety, depression, or slurred speech.
Answer

Question
Can I take Amantrel any time during the day? Should the dose be taken before meal?
Yes, Amantrel can be taken at any time during the day, with or without food. Try to take the medicine at about the same time each day, as directed by your doctor. Taking your medicine at the same time each day will have the best effect. It will also help you to remember when to take your medicine.
Answer

Question
Can Amantrel cause weight loss?
Decreased weight and body mass index may occur with continued Amantrel usage. If you have any concerns regarding weight loss consult your doctor or a nutritionist.
Answer

Question
Does Amantrel cause constipation?
Yes, constipation is a common side effect of Amantrel, though it does not occur in everyone. Consult your doctor or a dietician if constipation persists and is troublesome.
Answer

Question
Is Amantrel used for pain?
Though it is not an approved use, Amantrel has been shown to be effective in relieving pain related to nerve disorder. Amantrel is a prescription medicine, and you should take it for relief of pain only if advised by the doctor.
Answer

Question
Can Amantrel get you high?
The use of Amantrel may cause impulse control disorders in which you may have strong urges to gamble, increased sexual urges, intense urges to spend money, binge eating, and other intense urges. Additionally, there is the inability to control these urges. If such symptoms are experienced then dose reduction or tapered discontinuation should be considered.
Answer

Question
Does Amantrel affect fertility?
No, Amantrel is not known to affect fertility in humans.
Answer

Question
Does Amantrel cause fatigue?
Yes, Amantrel causes fatigue and sleepiness which may affect some patients’ ability to drive and operate machinery safely.
Answer
Question
What if you forget to take Amantrel?
If you miss a dose of Amantrel, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
Answer

Amantrel Capsule Reviews

Amantrel is used alone or in combination with other medicines to treat Parkinson’s disease. It can also be used to treat drug-induced movement disorder. It works by increasing the levels of a chemical called dopamine in the brain, which is important for controlling movement.

Amantrel is also used to prevents and treats influenza infection. The antiviral poperty of the medicine works against the viruses to prevent their and multiplication. Amantrel may be taken with or without food. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor.

If you have missed a dose, take it as soon as you remember it. You should finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor. This medicine may put you at a higher risk of having seizures, so it is better to talk to your doctor if you have any history of seizures or taking medication for it.

Some common side effects of Amantrel include nausea, dryness in the mouth, constipation, blurred vision, insomnia (difficulty sleeping), hallucinations, peripheral edema and balance disorder (loss of balance). It may initially cause dizziness and lowering of blood pressure while standing, so rise slowly and do not drive or do anything that requires mental focus until you know how this medicine affects you.

How Amantrel Capsule Works

Amantrel is a dopamine agonist that treats Parkinson's disease. It works by increasing the amount of dopamine, a chemical messenger in the brain which regulates body movements. It also has an antiviral property. It works against viruses to prevent their growth and multiplication. It also appears to restricts the viruses to release infectious chemicals (viral nucleic acid) to enter into the body. Thus, it prevents and treats influenza infection.

How to Use Amantrel Capsule

Take this medicine in the dose and duration as advised by your doctor. Amantrel may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Amantrel Capsule

  • In Treatment of Parkinson's disease: Amantrel is one of the most effective medications to relieve symptoms of Parkinson's disease such as tremors, muscle stiffness and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Uses of Amantrel Capsule

  • Treatment of Parkinson's disease

Amantrel Capsule Side Effects

Item form

Safety Tips

Alcohol  UNSAFE
It is unsafe to consume alcohol with Amantrel.
Kidney  CAUTION
Amantrel should be used with caution in patients with kidney disease. Dose adjustment of Amantrel may be needed. Please consult your doctor.Use of Amantrel is not recommended in patients with severe kidney disease.
Pregnancy  CONSULT YOUR DOCTOR
Amantrel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding  CONSULT YOUR DOCTOR
Amantrel is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving  UNSAFE
Amantrel may cause side effects which could affect your ability to drive.
Liver  CAUTION
Amantrel should be used with caution in patients with liver disease. Dose adjustment of Amantrel may be needed. Please consult your doctor.It may cause a transient increase in liver enzymes.

Quick Tips

  • It may cause blurring of vision or affect mental ability. Do not drive or do anything requiring concentration until you know how it affects you.
  • It may put you at a higher risk of having seizures. Talk to your doctor if you have a history of seizures or are taking medication for it.
  • Do not stop taking the medication suddenly without talking to your doctor.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform your doctor if you notice an urge to gamble, increased sexual urges, binge eating, or uncontrolled spending.
  • It can be taken with or without food.
  • Do not take extra medicine to make up for the missed dose.

References

  1. Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 619.
  2. ScienceDirect. Amantadine.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 48-49.
  4. Amantadine. Bridgewater, New Jersey: Vertical Pharmaceuticals, LLC; 1966 [revised Feb. 2018].
  5. Central Drugs Standard Control Organisation (CDSCO).
  6. Amantadine hydrochloride. Walsall, UK: Fontus Health Ltd.; 2019.
  7. Drugs.com. Amantadine Pregnancy and Breastfeeding Warnings.
  8. Amantadine hydrochloride. North Ryde, New South Wales: NOVARTIS Pharmaceuticals Australia Pty Limited; 2014.
  9. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 477.
  10. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amantadine. [Updated 2018 Oct 31].
  11. Amantadine Hydrochloride [Product Information]. Maple Grove, MN: Upsher-Smith Laboratories, LLC; 2022.

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