Crizalk 250mg Capsule
Product Info
| Prescription required | Yes |
| Marketer | Pfizer Ltd |
| Active Ingredient | Crizotinib (250mg) |
| Storage | Store below 30°C |
| Chemical Class | Piperidine and Aminopyridine Derivative |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Tyrosine kinase inhibitors |
| User Rating | 4.6 |
| User Reviews | 435 |
FAQ
How does Crizalk 250mg work?
Crizalk 250mg works by inhibiting an enzyme called as tyrosine kinase that transmits the signal for growth and spread of cancer cells.
How is Crizalk 250mg administered?
Crizalk 250mg is generally administered in the form of capsules to be taken orally.
What is Crizalk 250mg used for?
Crizalk 250mg is used for treating non small-cell lung cancer caused due to a mutation or defect in a gene called as anaplastic lymphoma kinase in cancer cells in patients who have not responded to previous therapies.
What if you forget to take Crizalk Capsule?
If you miss a dose of Crizalk 250mg, skip it and continue with your normal schedule. Do not double the dose.
Crizalk 250mg Capsule Reviews
Crizalk 250mg is used in the treatment of non-small cell lung cancer that is locally advanced or has spread to other areas of the body.
Crizalk 250mg should be taken with food or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, edema (swelling), and diarrhea are some common side effects of this medicine. Some serious side effects that might occur which need doctor consultation include severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits. Your doctor may perform some blood tests during the treatment to check for liver function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Crizalk 250mg should be taken with food or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, edema (swelling), and diarrhea are some common side effects of this medicine. Some serious side effects that might occur which need doctor consultation include severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits. Your doctor may perform some blood tests during the treatment to check for liver function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
How Crizalk 250mg Capsule Works
Crizalk 250mg is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
How to Use Crizalk 250mg Capsule
Take this medicine in the dose and duration as advised by your doctor. Crizalk 250mg may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Crizalk 250mg Capsule
- In Non-small cell lung cancer: Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Crizalk 250mg helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Uses of Crizalk 250mg Capsule
- Non-small cell lung cancer
Crizalk 250mg Capsule Side Effects
Safety Tips
Pregnancy
CONSULT YOUR DOCTOR
Crizalk 250mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Crizalk 250mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Crizalk 250mg. Please consult your doctor.
Kidney
CAUTION
Crizalk 250mg should be used with caution in patients with severe kidney disease. Dose adjustment of Crizalk 250mg may be needed. Please consult your doctor.
Liver
CAUTION
Crizalk 250mg should be used with caution in patients with liver disease. Dose adjustment of Crizalk 250mg may be needed. Please consult your doctor.Use of Crizalk 250mg may not be advised in patients with the severe liver disease.
Driving
UNSAFE
Crizalk 250mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Quick Tips
- Do not take Crizalk 250mg if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
- Crizalk 250mg helps in the treatment of non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
- Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
- Take it at the same time each day, with or without food.
- It may cause dizziness or blurring of vision. Don't drive or do anything requiring concentration until you know how it affects you.
- Diarrhea, nausea and vomiting may occur with Crizalk 250mg. Stay hydrated and inform your doctor if it persists.
- Inform your doctor if you experience severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits.
References
- Crizotinib. Dublin, Ireland: Pfizer Ireland Pharmaceuticals; Aug. 2011.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 331.
- Crizotinib. Bruxelles Belgium: Pfizer Europe; 23 Oct. 2012 [revised Feb. 2019].
- Central Drugs Standard Control Organisation (CDSCO).