Evermide 25mg Capsule
Product Info
| Prescription required | Yes |
| Marketer | Neova Biogene Private Limited |
| Active Ingredient | Lenalidomide (25mg) |
| Storage | Store below 30°C |
| Chemical Class | Phthalimide and Piperidone Derivative |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Thalidomide & its Immunomodulatory derivatives (IMiDs) |
| User Rating | 4.7 |
| User Reviews | 692 |
FAQ
What are the side effects of Evermide 25mg?
Evermide 25mg may cause side effects which include diarrhea, constipation, stomach pain, loss of appetite, weight loss, weakness, dizziness, change in ability to taste, and pain or burning of the tongue, mouth, or throat. The medicine may also cause decreased sense of touch, burning or tingling in the hands or feet, difficulty falling asleep or staying asleep, depression, and joint, muscle, bone, or back pain. You may also experience sweating, dry skin, abnormal hair growth in women, uncontrollable shaking of a part of the body, decrease in sexual desire or ability or painful, frequent, or urgent urination. Tell your doctor if any of these symptoms are severe or do not go away.
Do I need to get any blood tests done while on Evermide 25mg?
Your doctor will ask you to have a blood test before treatment and every week for the first 8 weeks of treatment. You may need to continue taking the blood tests at least every month after treatment with Evermide 25mg ends. Frequent blood tests are important as Evermide 25mg may decrease the blood cells that help fight infection (white blood cells) and help the blood to clot (platelets).
Can Evermide 25mg be given to patients who are on dialysis?
Yes, Evermide 25mg is given to dialysis patients after the dialysis is done. However, the doctor may adjust the dose if needed in patients undergoing.
Can Evermide 25mg cause cancer?
People with multiple myeloma (a form of cancer that begins in plasma cells, a type of white blood cell) who receive melphalan (chemotherapy) and a blood stem cell transplant with the addition of Evermide 25mg have a higher risk of developing new cancers. These types of cancers may include certain blood cancers (acute myelogenous leukemia or AML) and a type of lymphoma called Hodgkin lymphoma. Talk to your doctor about your risk of developing new cancers if you are taking Evermide 25mg.
Can I take Evermide 25mg empty stomach?
Evermide 25mg may be taken with or without food. Always take it exactly as prescribed by your doctor. Do not crush, cut or chew the capsules. Swallow it whole with water. You should take Evermide 25mg at about the same time on the scheduled days.
Do I need to use birth control methods while using Evermide 25mg?
Women who can become pregnant must use two acceptable forms of birth control for 4 weeks before they begin taking Evermide 25mg. Continue using contraceptives during your treatment, including the times when your doctor tells you to temporarily stop taking Evermide 25mg, and for 4 weeks after your final dose. In men, Evermide 25mg may pass into the semen while they are on treatment. Therefore, men must always use a latex condom every time they have sexual contact, even if they have had a vasectomy (surgery that prevents a man from causing a pregnancy). Use the contraceptive while you are taking Evermide 25mg, during any breaks in your treatment, and for 4 weeks after your final dose.
What if you forget to take Evermide Capsule?
If you miss a dose of Evermide 25mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Evermide 25mg Capsule Reviews
Evermide 25mg belongs to a group of medicines that affect how your immune system works. $It is used in the treatment of multiple myeloma and myelodysplastic syndrome.
Evermide 25mg can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include headache, weakness, nausea, rash, and dizziness amongst others. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Hence, take caution while performing the activity that might increase your chances of bleeding or avoid contact with people suffering from an infection such as a cold. Regular blood tests are required to check your blood cells while on treatment.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You are advised to drink plenty of fluids to stay hydrated while taking this medicine.
How Evermide 25mg Capsule Works
Evermide 25mg is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells. It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.
How to Use Evermide 25mg Capsule
Take this medicine in the dose and duration as advised by your doctor. Evermide 25mg may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Evermide 25mg Capsule
- In Treatment of Multiple myeloma: If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Evermide 25mg may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
- In Treatment of Myelodysplastic syndrome: Myelodysplastic Syndromes (MDS) are a group of rare blood disorders characterized by abnormal development of blood cells in the bone marrow. In MDS, the bone marrow fails to produce enough healthy and fully matured blood cells, leading to low blood cell counts, which can result in anemia, infections, and bleeding problems.Evermide 25mg is used to treat certain types of MDS, specifically those associated with a specific part of the chromosomes in the blood cells. It works by helping the immune system make more healthy blood cells in the bone marrow. Evermide 25mg helps improve the production of red blood cells, reducing the need for frequent blood transfusions and making them feel better. It is important to check-up and monitor regularly to make sure it is safe and effective.
Uses of Evermide 25mg Capsule
- Treatment of Multiple myeloma
- Treatment of Myelodysplastic syndrome
Evermide 25mg Capsule Side Effects
Safety Tips
Liver
CAUTION
Evermide 25mg should be used with caution in patients with liver disease. Dose adjustment of Evermide 25mg may be needed. Please consult your doctor.
Pregnancy
UNSAFE
Evermide 25mg is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Driving
UNSAFE
Evermide 25mg may cause side effects which could affect your ability to drive.You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Evermide 25mg and this may affect your ability to drive.
Kidney
CAUTION
Evermide 25mg should be used with caution in patients with kidney disease. Dose adjustment of Evermide 25mg may be needed. Please consult your doctor.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Evermide 25mg. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Evermide 25mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Quick Tips
- You should use proper contraceptive methods at least 4 weeks before, during and until 4 weeks after stopping treatment.
- It may cause dehydration. Drink plenty of water to stay hydrated while taking medication.
- It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective while going out.
- You should inform your doctor or dentist that you are taking Evermide 25mg before you receive any medical or dental care, emergency care, or surgery.
- Avoid activities that may cause bruising or injury and avoid contact with people who have colds or infections.
- You may be monitored with regular blood tests before and during the treatment as lenalidomide may cause a fall in the white blood cells and platelets, required to fight infection, Hemoglobin and blood clotting.
- Woman of childbearing potential will be required to undergo pregnancy tests before and after the treatment.
- You may be at risk of developing acute myelogenous leukemia, fatal liver problems, severe skin reactions, and fatal heart problems during treatment with Evermide 25mg. You should discuss in advance the benefits and risks of taking this medicine.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- It is not recommended for use in children and adolescents under 18 years.
References
- Lenalidomide. Summit, New Jersey: Celgene Corporation.
- Lenalidomide Capsules [Package Insert]. Bangalore, India: Biocon Limited.
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1742.
- Central Drugs Standard Control Organisation (CDSCO).
- LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012. Lenalidomide. [Updated 2022 Aug 30].
- Lenalidomide [Prescribing Information]. Nantou City, Taiwan: Lotus Pharmaceutical Co., Ltd.; 2022.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 784-85.