I 20 Capsule

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Prism Life Sciences Ltd
Active Ingredient	Isotretinoin (20mg)
Storage	Store below 30°C
Chemical Class	Retinoid
Habit Forming	No
Therapeutic Class	DERMA
Action Class	Retinoids- First generation
User Rating	4.7
User Reviews	507

FAQ

Why is I 20 so dangerous during pregnancy?

If pregnancy occurs during treatment with I 20 then, there is an extremely high risk that the baby may be born with severe birth defects.

Is I 20 a steroid?

No, I 20 is a retinoid (vitamin A) which is used to treat severe types of acne.

What are the long-term side effects of I 20?

A normal course of treatment of I 20 is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Does I 20 affect male fertility?

No, I 20 does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.

Does I 20 damage your liver?

There may be a transient increase in liver enzymes with I 20 use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of I 20.

Is I 20 safe to use?

I 20 should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, I 20 should not be used by pregnant women because it can cause severe birth defects.

What are the recommended tests during I 20 therapy?

Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.

Is the effect of I 20 permanent?

It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with I 20 has shown that the symptoms in the patients with acne may continue to improve following treatment with I 20.

Can I 20 cause cancer?

No, there are no reports of I 20 causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.

What if you forget to take I 20?

If you miss a dose of I 20, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

I 20 Capsule Reviews

I 20 belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.

I 20 should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.

The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.

I 20 may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Additionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.

How I 20 Capsule Works

I 20 is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

How to Use I 20 Capsule

Take this medicine in the dose and duration as advised by your doctor. I 20 is to be taken with food.

Benefits of I 20 Capsule

In Treatment of Acne: I 20 helps treat acne by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep taking it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.

Uses of I 20 Capsule

Treatment of Acne

I 20 Capsule Side Effects

Safety Tips

Breast feeding ^{CONSULT YOUR DOCTOR}

I 20 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving ^UNSAFE

I 20 may cause side effects which could affect your ability to drive.Your night vision may get worse during your treatment. This can happen suddenly. Drowsiness and dizziness have been reported very rarely. This may affect your driving ability.

Liver ^UNSAFE

I 20 is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Alcohol ^CAUTION

Caution is advised when consuming alcohol with I 20. Please consult your doctor.

Pregnancy ^UNSAFE

I 20 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Kidney ^CAUTION

I 20 should be used with caution in patients with kidney disease. Dose adjustment of I 20 may be needed. Please consult your doctor.

Quick Tips

You have been prescribed I 20 for the treatment of severe acne.
Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
Do not take I 20 if you are pregnant, planning pregnancy or breastfeeding.
It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
Avoid exposure to sunlight while using I 20. Use protective measures such as sunscreen or protective clothing.
Take it with food.

References

CiplaMed. Isotretinoin [Prescribing Information]. [Last Revised: 29 Nov. 2019].
Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.
Isotretinoin. Nutley, New Jersey: Roche Laboratories Inc.; 2002.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.
Central Drugs Standard Control Organisation (CDSCO).
Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
Central Drugs Standard Control Organization. Safety guidelines for isotretinoin. 2018.
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.