Ibrukem Capsule
Product Info
| Prescription required | Yes |
| Marketer | Alkem Laboratories Ltd |
| Active Ingredient | Ibrutinib (140mg) |
| Chemical Class | Diphenylethers Derivative |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Bruton's tyrosine kinase (BTK) inhibitors |
| User Rating | 4.5 |
| User Reviews | 340 |
FAQ
Ibrukem Capsule Reviews
Ibrukem is used in the treatment of mantle-cell lymphoma and blood cancer (chronic lymphocytic leukemia). It is also used in chronic lymphocytic leukaemia who have received at least one prior therapy.
Ibrukem is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your response to treatment. Your doctor may get regular blood tests to check number of blood cells during treatment with this medicine. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. It may cause headache, diarrhea, and nausea as its side effects.
Ibrukem is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your response to treatment. Your doctor may get regular blood tests to check number of blood cells during treatment with this medicine. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. It may cause headache, diarrhea, and nausea as its side effects.
How Ibrukem Capsule Works
Ibrukem is a Bruton's tyrosine kinase inhibitor. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
How to Use Ibrukem Capsule
Take this medicine in the dose and duration as advised by your doctor. Ibrukem may be taken with or without food, but it is better to take it at a fixed time.
Uses of Ibrukem Capsule
- Blood cancer (Chronic lymphocytic leukemia)
- Mantle-cell lymphoma
Ibrukem Capsule Side Effects
- Low blood platelets
- Peripheral edema
- Musculoskeletal (bone, muscle or joint) pain
- Stomatitis (Inflammation of the mouth)
- Headache
- Urinary tract infection
- High blood pressure
- Nausea
- Pneumonia
- Hemorrhage
- Weight loss
- Subdural hematoma
- Decreased white blood cell count (neutrophils)
- Fever
- Fatigue
- Rash
- Anemia (low number of red blood cells)
- Muscle spasm
- Cough
- Second primary malignancies
- Diarrhea
- Bruising
- Dry eye
Safety Tips
Liver
CAUTION
Ibrukem should be used with caution in patients with liver disease. Dose adjustment of Ibrukem may be needed. Please consult your doctor.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ibrukem. Please consult your doctor.
Kidney
CAUTION
Ibrukem should be used with caution in patients with kidney disease. Dose adjustment of Ibrukem may be needed. Please consult your doctor.
Breast feeding
CAUTION
Ibrukem should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Pregnancy
CONSULT YOUR DOCTOR
Ibrukem is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Driving
UNSAFE
Ibrukem may cause side effects which could affect your ability to drive.
Quick Tips
- Your doctor may get regular blood tests done to monitor your liver function and blood cell count in your blood.
- Do not skip any dose and complete the course as suggested by your doctor.
- It is advisable to stay hydrated and drink plenty of fluids while taking this medication.
- Take it at the same time every day, either with or without food.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
References
- Central Drugs Standard Control Organisation (CDSCO).
- Ibrutinib. Beerse Belgium: Janssen Pharmaceutica NV;