Lenangio 5mg Capsule
Product Info
| Prescription required | Yes |
| Marketer | Dr Reddy's Laboratories Ltd |
| Active Ingredient | Lenalidomide (5mg) |
| Storage | Store below 30°C |
| Chemical Class | Phthalimide and Piperidone Derivative |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Thalidomide & its Immunomodulatory derivatives (IMiDs) |
| User Rating | 5.0 |
| User Reviews | 449 |
FAQ
Can Lenangio 5mg cause cancer?
People with multiple myeloma (a form of cancer that begins in plasma cells, a type of white blood cell) who receive melphalan (chemotherapy) and a blood stem cell transplant with the addition of Lenangio 5mg have a higher risk of developing new cancers. These types of cancers may include certain blood cancers (acute myelogenous leukemia or AML) and a type of lymphoma called Hodgkin lymphoma. Talk to your doctor about your risk of developing new cancers if you are taking Lenangio 5mg.
Can I take Lenangio 5mg empty stomach?
Lenangio 5mg may be taken with or without food. Always take it exactly as prescribed by your doctor. Do not crush, cut or chew the capsules. Swallow it whole with water. You should take Lenangio 5mg at about the same time on the scheduled days.
What are the side effects of Lenangio 5mg?
Lenangio 5mg may cause side effects which include diarrhea, constipation, stomach pain, loss of appetite, weight loss, weakness, dizziness, change in ability to taste, and pain or burning of the tongue, mouth, or throat. The medicine may also cause decreased sense of touch, burning or tingling in the hands or feet, difficulty falling asleep or staying asleep, depression, and joint, muscle, bone, or back pain. You may also experience sweating, dry skin, abnormal hair growth in women, uncontrollable shaking of a part of the body, decrease in sexual desire or ability or painful, frequent, or urgent urination. Tell your doctor if any of these symptoms are severe or do not go away.
Do I need to use birth control methods while using Lenangio 5mg?
Women who can become pregnant must use two acceptable forms of birth control for 4 weeks before they begin taking Lenangio 5mg. Continue using contraceptives during your treatment, including the times when your doctor tells you to temporarily stop taking Lenangio 5mg, and for 4 weeks after your final dose. In men, Lenangio 5mg may pass into the semen while they are on treatment. Therefore, men must always use a latex condom every time they have sexual contact, even if they have had a vasectomy (surgery that prevents a man from causing a pregnancy). Use the contraceptive while you are taking Lenangio 5mg, during any breaks in your treatment, and for 4 weeks after your final dose.
Can Lenangio 5mg be given to patients who are on dialysis?
Yes, Lenangio 5mg is given to dialysis patients after the dialysis is done. However, the doctor may adjust the dose if needed in patients undergoing.
Do I need to get any blood tests done while on Lenangio 5mg?
Your doctor will ask you to have a blood test before treatment and every week for the first 8 weeks of treatment. You may need to continue taking the blood tests at least every month after treatment with Lenangio 5mg ends. Frequent blood tests are important as Lenangio 5mg may decrease the blood cells that help fight infection (white blood cells) and help the blood to clot (platelets).
What if you forget to take Lenangio Capsule?
If you miss a dose of Lenangio 5mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Lenangio 5mg Capsule Reviews
Lenangio 5mg belongs to a group of medicines that affect how your immune system works. $It is used in the treatment of multiple myeloma and myelodysplastic syndrome.
Lenangio 5mg can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include headache, weakness, nausea, rash, and dizziness amongst others. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Hence, take caution while performing the activity that might increase your chances of bleeding or avoid contact with people suffering from an infection such as a cold. Regular blood tests are required to check your blood cells while on treatment.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You are advised to drink plenty of fluids to stay hydrated while taking this medicine.
How Lenangio 5mg Capsule Works
Lenangio 5mg is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells. It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.
How to Use Lenangio 5mg Capsule
Take this medicine in the dose and duration as advised by your doctor. Lenangio 5mg may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Lenangio 5mg Capsule
- In Treatment of Multiple myeloma: If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Lenangio 5mg may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
- In Treatment of Myelodysplastic syndrome: Myelodysplastic Syndromes (MDS) are a group of rare blood disorders characterized by abnormal development of blood cells in the bone marrow. In MDS, the bone marrow fails to produce enough healthy and fully matured blood cells, leading to low blood cell counts, which can result in anemia, infections, and bleeding problems.Lenangio 5mg is used to treat certain types of MDS, specifically those associated with a specific part of the chromosomes in the blood cells. It works by helping the immune system make more healthy blood cells in the bone marrow. Lenangio 5mg helps improve the production of red blood cells, reducing the need for frequent blood transfusions and making them feel better. It is important to check-up and monitor regularly to make sure it is safe and effective.
Uses of Lenangio 5mg Capsule
- Treatment of Myelodysplastic syndrome
- Treatment of Multiple myeloma
Lenangio 5mg Capsule Side Effects
Safety Tips
Breast feeding
CONSULT YOUR DOCTOR
Lenangio 5mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Lenangio 5mg may cause side effects which could affect your ability to drive.You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Lenangio 5mg and this may affect your ability to drive.
Pregnancy
UNSAFE
Lenangio 5mg is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Kidney
CAUTION
Lenangio 5mg should be used with caution in patients with kidney disease. Dose adjustment of Lenangio 5mg may be needed. Please consult your doctor.
Liver
CAUTION
Lenangio 5mg should be used with caution in patients with liver disease. Dose adjustment of Lenangio 5mg may be needed. Please consult your doctor.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lenangio 5mg. Please consult your doctor.
Quick Tips
- It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective while going out.
- You may be at risk of developing acute myelogenous leukemia, fatal liver problems, severe skin reactions, and fatal heart problems during treatment with Lenangio 5mg. You should discuss in advance the benefits and risks of taking this medicine.
- You may be monitored with regular blood tests before and during the treatment as lenalidomide may cause a fall in the white blood cells and platelets, required to fight infection, Hemoglobin and blood clotting.
- It may cause dehydration. Drink plenty of water to stay hydrated while taking medication.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- You should use proper contraceptive methods at least 4 weeks before, during and until 4 weeks after stopping treatment.
- You should inform your doctor or dentist that you are taking Lenangio 5mg before you receive any medical or dental care, emergency care, or surgery.
- Woman of childbearing potential will be required to undergo pregnancy tests before and after the treatment.
- It is not recommended for use in children and adolescents under 18 years.
- Avoid activities that may cause bruising or injury and avoid contact with people who have colds or infections.
References
- Lenalidomide Capsules [Package Insert]. Bangalore, India: Biocon Limited.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 784-85.
- LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012. Lenalidomide. [Updated 2022 Aug 30].
- Central Drugs Standard Control Organisation (CDSCO).
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1742.
- Lenalidomide. Summit, New Jersey: Celgene Corporation.
- Lenalidomide [Prescribing Information]. Nantou City, Taiwan: Lotus Pharmaceutical Co., Ltd.; 2022.