Pgl-M 75 Capsule
Product Info
| Prescription required | Yes |
| Marketer | Mission Research Laboratories Pvt Ltd |
| Active Ingredient | Benfotiamine (7.5mg) + Folic Acid (0.75mg) + Methylcobalamin (750mcg) + Pregabalin (75mg) + Vitamin B6 (Pyridoxine) (1.5mg) |
| Storage | Store below 30°C |
| Habit Forming | No |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| User Rating | 4.7 |
| User Reviews | 616 |
FAQ
Will a higher than the recommended dose of Pgl-M 75 be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Can I stop taking Pgl-M 75 when my pain is relieved?
No, you should not stop taking Pgl-M 75 even if your pain is relieved. Continue to take it as advised by your doctor. If you stop taking Pgl-M 75 suddenly, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. You may need to gradually taper the use of Pgl-M 75 before you stop the medication completely.
How often should I see the doctor?
You may need to see your doctor regularly if you have started to take Pgl-M 75. However, consult your doctor if the recommended dosage does not relieve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Can the use of Pgl-M 75 cause sleepiness or drowsiness?
Yes, Pgl-M 75 may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights, or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
How to manage weight gain associated with the use of Pgl-M 75?
Pgl-M 75 can make you feel hungry, making you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, eat fruits, vegetables, and low-calorie foods. Regular exercise will also help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteady when walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing, and increased heartbeat.
Can I drink alcohol while taking Pgl-M 75?
No, do not drink alcohol while taking Pgl-M 75. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Pgl-M 75.
What if I forget to take Pgl-M 75?
If you forget to take the scheduled dose of Pgl-M 75 and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.
How long will Pgl-M 75 take to act?
An initial benefit with Pgl-M 75 may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefit. It may take even longer for some patients.
Are there any serious side effects associated with the use of Pgl-M 75?
Serious side effects with Pgl-M 75 are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts, or swelling of limbs (hands, legs, or feet). Stop taking Pgl-M 75 and contact your doctor if you have any signs of these serious side effects. Signs of an allergic reaction include swelling of your face, mouth, lips, gums, tongue, and neck, trouble in breathing, skin rash, hives (raised bumps), or blisters. Pay attention to sudden changes in mood, behaviors, thoughts, or feelings a these may be a symptom of suicidal thoughts.
What is Pgl-M 75?
Pgl-M 75 is a combination of five medicines: Pregabalin, Methylcobalamin, Folic acid, Benfotiamine, and vitamin B6. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
What are the instructions for the storage and disposal of Pgl-M 75?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
What if you forget to take Pgl-M Capsule?
If you miss a dose of Pgl-M 75, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Pgl-M 75 Capsule Reviews
Pgl-M 75 is a prescription medicine that helps relieve neuropathic pain (pain from damaged nerves). It strengthens the nerves and relieves nerve pain.
Pgl-M 75 can be taken with or without food. It should be used in the dose and duration as prescribed by your doctor. It is advised to take this medicine at a fixed time. Do not take more than the recommended dose.
Pgl-M 75 is usually safe with very minimal side effects. However, if you experience severe diarrhea, vomiting, constipation, or any signs of an allergic reaction, please consult your doctor. Also, before taking this medicine, tell your doctor about all other health conditions that you have.
Inform your doctor if you are taking any other medicines or if you are pregnant or breastfeeding. It is not advised to drive after taking this medicine as it may cause sleepiness or dizziness and may affect your ability to concentrate and react.
How Pgl-M 75 Capsule Works
Pgl-M 75 is a combination of five medicines: Benfotiamine, Folic Acid, Methylcobalamin, Pregabalin and Vitamin B6 (Pyridoxine). Benfotiamine and Folic Acid provide essential nutrients to the nerves. Methylcobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
How to Use Pgl-M 75 Capsule
Take this medicine in the dose and duration as advised by your doctor. Pgl-M 75 may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Pgl-M 75 Capsule
- In Treatment of Neuropathic pain: Pgl-M 75 is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. Pregabalin, an active ingredient of this medicine, is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that improve nerve conduction.Taking this medicine regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.
Uses of Pgl-M 75 Capsule
- Treatment of Neuropathic pain
Pgl-M 75 Capsule Side Effects
Safety Tips
Driving
UNSAFE
Pgl-M 75 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pgl-M 75 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pgl-M 75 may not be needed in these patients. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pgl-M 75 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Liver
CAUTION
Pgl-M 75 should be used with caution in patients with severe liver disease. Dose adjustment of Pgl-M 75 may be needed. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pgl-M 75 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Alcohol
CAUTION
Caution is advised when consuming alcohol with Pgl-M 75. Please consult your doctor.
Quick Tips
- Inform your doctor if you are taking any other pain-relieving medicines.
- Let your doctor know if you are pregnant or breastfeeding.
- Pgl-M 75 is used to treat certain types of long-lasting pain caused by damage to nerves.
- Along with taking Pgl-M 75, your doctor might advise you to undergo physiotherapy to get relief from pain.
- It might cause dizziness and sleepiness, do not drive or use tools or machines.
References
- Pregabalin & Methylcobalamin [Patient Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2017.
- National Health Service. Folic Acid.
- Combs Jr. GF, McClung JP. The Vitamins: Fundamental Aspects in Nutrition and Health. 5th ed. Westborough, MA: Academic Press; 2017.
- Coates PM, Betz JM, Blackman MR, et al. (Editors). Encyclopedia of Dietary Supplements. 2nd ed. Boca Raton, FL: CRC Press; 2010.
- Markova N, Bazhenova N, Anthony DC, et al. Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2017;75:148-156.