Pregameth Capsule


Product Info

Prescription required Yes
Marketer Adison Pharmaceuticals
Active Ingredient Alpha Lipoic Acid (100mg) + Folic Acid (1.5mg) + Methylcobalamin (750mcg) + Pregabalin (75mg) + Vitamin B6 (Pyridoxine) (3mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassNEURO CNS
User Rating4.3
User Reviews677

FAQ

Question
How to manage weight gain associated with the use of Pregameth?
Pregameth can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Answer

Question
Can I drink alcohol while taking Pregameth?
No, do not drink alcohol while you are taking Pregameth. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Pregameth.
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Question
What is Pregameth?
Pregameth is a combination of five medicines: Pregabalin, Methylcobalamin, Folic acid, Alpha lipoic acid, and Vitamin B6. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
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Question
Will a higher than the recommended dose of Pregameth be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
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Question
Are there any serious side effects associated with the use of Pregameth?
Serious side effects because of Pregameth are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Pregameth and contact your health care provider if you have any signs of these serious side effects. Signs of allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck, trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to sudden changes in mood, behaviors, thoughts, or feelings as these may be a symptom of suicidal thoughts.
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Question
What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
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Question
Can I stop taking Pregameth when my pain is relieved?
No, you should not stop taking Pregameth even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pregameth, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Pregameth before you stop the medication completely.
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Question
What if I forget to take Pregameth?
If you forget to take the scheduled dose of Pregameth and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.
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Question
How long will Pregameth take to act?
An initial benefit with Pregameth may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefit. It may take longer in some patients.
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Question
How often should I see the doctor?
You may need to see your doctor regularly if you have started to take Pregameth. However, consult your doctor if the recommended dosage does not improve your symptoms or you continue experiencing some unwanted side effect that affect your routine activities.
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Question
Can the use of Pregameth cause sleepiness or drowsiness?
Yes, Pregameth may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
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Question
What are the instructions for the storage and disposal of Pregameth?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Answer
Question
What if you forget to take Pregameth?
If you miss a dose of Pregameth, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Pregameth Capsule Reviews

Pregameth is used to treat neuropathic pain. It decreases the pain by controlling calcium channel activity and by decreasing the production of a substance that protects nerve fibers and rejuvenates damaged nerve cells.

Pregameth can be taken on empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor.

Common side effects of this medicine include dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also cause nasopharyngitis, increased appetite, confusion, difficulty in sleeping, decreased libido, tremor, vision blurred, and vertigo. Inform your doctor if you develop any unusual changes in the mood or behavior, new or worsening depression, or suicidal thoughts. It is better to avoid alcohol while taking this medicine as it can enhance the dizziness effect of the drug.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

How Pregameth Capsule Works

Pregameth is a combination of five medicines: Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin and Vitamin B6 (Pyridoxine). Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on the brain and nerve tissues. Folic Acid provides essential nutrients to the nerves. Methylcobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

How to Use Pregameth Capsule

Take this medicine in the dose and duration as advised by your doctor. Pregameth is to be taken empty stomach.

Uses of Pregameth Capsule

  • Neuropathic pain

Pregameth Capsule Side Effects

Item form

Safety Tips

Kidney  SAFE IF PRESCRIBED
Pregameth is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pregameth may not be needed in these patients. Please consult your doctor.
Driving  UNSAFE
Pregameth may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Pregnancy  CONSULT YOUR DOCTOR
Pregameth may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Liver  SAFE IF PRESCRIBED
Pregameth is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pregameth may not be needed in these patients. Please consult your doctor.
Breast feeding  CONSULT YOUR DOCTOR
Pregameth is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alcohol  CAUTION
Caution is advised when consuming alcohol with Pregameth. Please consult your doctor.

Quick Tips

  • Avoid consuming alcohol when taking this medicine, as it may cause excessive sleepiness or drowsiness.
  • Do not stop taking the medication suddenly without talking to your doctor.
  • Its side effects are usually mild and go away by themselves.
  • It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Pregameth helps treat nerve pain caused by diabetes, shingles or an injury.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

References

  1. Pregabalin, Methylcobalamin, Alpha Lipoic Acid, Pyridoxine Hydrochloride and Folic Acid [Patient Information Sheet]. Solan, HP: Innova Captab Ltd.; 2021.
  2. MedlinePlus. Vitamin B12.
  3. Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009.
  4. Mayo Clinic. Vitamin B-6.

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