S-One Trio Capsule


Product Info

Prescription required Yes
Marketer Intas Pharmaceuticals Ltd
Active Ingredient Gimeracil (5.8mg) + Oteracil (15.8mg) + Tegafur (20mg)
Habit FormingNo
Therapeutic ClassANTI NEOPLASTICS
User Rating4.7
User Reviews526

FAQ

Question
What is S-One Trio used for?
S-One Trio is used in adults for the treatment of stomach cancer when given in combination with another medication named cisplatin.
Answer

Question
I am noticing a change in my taste. How shall I improve my taste?
You may experience a metallic taste or find that food has no taste at all. You may dislike foods or beverages that you liked before receiving cancer treatment. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You can also add extra flavor or seasonings to your food.
Answer

Question
Are there any precautions for tingling sensation and numbness in my arms and legs?
This medicine causes tingling, numbness, pain, or burning sensation in the arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dosage or schedule.
Answer

Question
Does S-One Trio cause hair loss?
Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.
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Question
How will you know that S-One Trio is working?
Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.
Answer

Question
Can S-One Trio affect my fertility?
There are no data available on the effect of this medicine in combination with cisplatin. In case of any doubts, it is always better to talk to your doctor if you have concerns about fertility.
Answer

Question
I have noticed some changes in my skin after taking S-One Trio? What should I do?
Use a moisturizer to get relief from rashes, dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will become better once treatment is stopped.
Answer

Question
Can S-One Trio be used during pregnancy?
No, this medicine should not be used during pregnancy as it can harm the unborn child. Avoid getting pregnant and use an effective method of birth control during your treatment and for at least 6 months after the last dose of S-One Trio.
Answer

Question
How to relieve constipation during treatment with S-One Trio?
To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.
Answer
Question
What if you forget to take S-One Trio?
If you miss a dose of S-One Trio, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

S-One Trio Capsule Reviews

S-One Trio is a combination medicine used in the treatment of stomach cancer. It can be used alone or in combination with some medicines as part of combination chemotherapy. It works by interfering with the growth of cancer cells, which are eventually destroyed.

S-One Trio should be taken with water at least 1 hour before or 1 hour after a meal. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include bone marrow suppression, acute renal failure, diarrhea, dehydration, electrolyte disturbance, and lacrimal disorders. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, inform your doctor if you have medical conditions involving blood, kidney, and liver or if you are suffering from any breathing disorder.  This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

How S-One Trio Capsule Works

S-One Trio is a combination of anticancer medications. Tegafur gets converted to its active form known as 5-fluorouracil (5-FU) that inhibits the synthesis and function of genetic material DNA and RNA and prevents the growth of cancer cells. Gimeracil prevents the breakdown of 5-FU, which helps maintain high concentrations of 5-FU against cancer cells. Oteracil suppresses 5-FU’s gastrointestinal toxicity.

How to Use S-One Trio Capsule

Take this medicine in the dose and duration as advised by your doctor. S-One Trio is to be taken empty stomach.

Benefits of S-One Trio Capsule

  • In Treatment of Stomach cancer: Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. S-One Trio helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

Uses of S-One Trio Capsule

  • Treatment of Stomach cancer

S-One Trio Capsule Side Effects

Item form

Safety Tips

Driving  UNSAFE
S-One Trio may cause side effects which could affect your ability to drive.S-One Trio can cause fatigue, dizziness, blurred vision, and nausea when used in combination with cisplatin.
Pregnancy  CONSULT YOUR DOCTOR
S-One Trio is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Kidney  CAUTION
S-One Trio should be used with caution in patients with kidney disease. Dose adjustment of S-One Trio may be needed. Please consult your doctor.
Liver  SAFE IF PRESCRIBED
S-One Trio is safe to use in patients with liver disease. No dose adjustment of S-One Trio is recommended.
Breast feeding  UNSAFE
S-One Trio is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with S-One Trio. Please consult your doctor.

Quick Tips

  • To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals. If you vomit a dose of medication, make sure you tell your doctor. Do not replace the dose that has been vomited.
  • You may be at risk of infection, so try to avoid crowds or people with colds, gargle upon returning home, and wash your hands before meals and before and after using the bathroom.
  • Decreased sensation, numbness, and tingling in fingers and toes may worsen with repeated doses of S-One Trio. It is important to report this to your doctor.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists. If you experience diarrhea, avoid high-fiber, fatty, and spicy foods.
  • To prevent bleeding, avoid hard work or strenuous sports to prevent injuries and bruises.

References

  1. Tegafur, Gimeracil and Oteracil Capsules [Package Insert]. Torrent Pharmaceuticals Ltd.; 2022.

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