Aplevant 0.75mg Pre-filled Pen

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Lupin Ltd
Active Ingredient	Dulaglutide (0.75mg)
Storage	Store in a refrigerator (2 - 8°C). Do not freeze.
Chemical Class	Glucagon-like Peptide-1 (GLP-1) Analogue
Habit Forming	No
Therapeutic Class	ANTI DIABETIC
Action Class	Insulin Secretogogues: GLP-1 agonists
User Rating	4.8
User Reviews	520

FAQ

Can Aplevant 0.75mg Pre-filled Pen be used with other diabetes medicine?

Yes, Aplevant 0.75mg Pre-filled Pen can be used alone or in combination with other diabetes medicines only if prescribed by your doctor.

Can diabetes be cured?

Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.

How is Aplevant 0.75mg Pre-filled Pen administered?

Aplevant 0.75mg Pre-filled Pen is injected under the skin (subcutaneously) of your stomach, thigh, or upper arm. It should not be injected into a muscle or vein. You can use the same area of your body each week to take the injection, but make sure that a different injection site is used within that area. Use Aplevant 0.75mg Pre-filled Pen as advised by your doctor. You can take it with or without food. If you are on insulin as well, do not mix insulin and Aplevant 0.75mg Pre-filled Pen in the same syringe. It is also recommended to check your blood sugar levels regularly.

Are there any potential risks of using Aplevant 0.75mg Pre-filled Pen?

Apart from the usual side effects of the medicine, Aplevant 0.75mg Pre-filled Pen has been found to cause Medullary Thyroid Carcinoma, a type of cancer of the thyroid gland. Its use may also increase the risk of inflammation of the pancreas commonly known as pancreatitis which is a serious and painful condition. Discontinue the medicine and contact your doctor immediately if you suspect any signs or symptoms of thyroid problems (lump in throat, hoarseness, and difficulty in speaking) or pancreatitis (stomach ache radiating to the back, upper abdominal pain, fever, nausea, and vomiting).

How does Aplevant 0.75mg Pre-filled Pen work for weight loss?

Aplevant 0.75mg Pre-filled Pen is used in type 2 diabetes mellitus. It improves blood sugar control and slows down digestion. This brings a feeling of fullness and satiety due to which the food intake by the patient decreases. As a result, the patient eats less which further helps in weight loss.

Can you take Aplevant 0.75mg Pre-filled Pen and insulin together?

Yes, your doctor may prescribe you this medicine with insulin if adequate glucose management is not obtained after using Aplevant 0.75mg Pre-filled Pen with other antidiabetic medicines. Insulin is often used early in the treatment of individuals with complications or symptoms of extremely high blood glucose levels. If insulin is used together with Aplevant 0.75mg Pre-filled Pen, there is often greater efficacy of both medications and improved treatment outcomes.

Is Aplevant 0.75mg Pre-filled Pen an insulin?

No, Aplevant 0.75mg Pre-filled Pen is not an insulin. It is a medicine used to lower blood sugar (glucose) levels in adults with type 2 diabetes mellitus. In type 2 diabetes insulin is deficient, and the insulin that your body produces does not work as well as it should. Aplevant 0.75mg Pre-filled Pen acts on the pancreas to increase insulin release, suppress glucagon secretion, and decrease glucose production from the liver. It also slows down the emptying of the stomach.

Can I take a protein-rich diet along with Aplevant 0.75mg Pre-filled Pen?

Yes, you can take a diet rich in protein along with Aplevant 0.75mg Pre-filled Pen. Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet. It is often recommended to consume about 2-3 teaspoons of proteins in the evening snacks to avert the chances of hypoglycemia.

What should I avoid while taking Aplevant 0.75mg Pre-filled Pen?

Avoid fried or fatty foods and foods high in sugar while taking Aplevant 0.75mg Pre-filled Pen to reduce the risk of nausea and vomiting. Eat slowly, and eat smaller meals that are light and bland.

Can diabetes cause kidney failure?

Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.

How to store Aplevant 0.75mg Pre-filled Pen?

Aplevant 0.75mg Pre-filled Pen should be refrigerated at 2°C - 8°C, but do not freeze it. Store Aplevant 0.75mg Pre-filled Pen in the original packaging to protect from light. Keep the medicine out of the reach of children. Do not use the medicine if you notice that the pen is damaged or the medicine has become cloudy/discolored or has lumps in it.

Can Aplevant 0.75mg Pre-filled Pen be used to treat type 1 diabetes?

No, Aplevant 0.75mg Pre-filled Pen should not be used in patients with type 1 diabetes mellitus or for the treatment of patients with diabetic ketoacidosis.

Is regular self-monitoring of blood sugar required while taking Aplevant 0.75mg Pre-filled Pen?

Regular self-monitoring of blood sugar is not needed in order to adjust the dose of Aplevant 0.75mg Pre-filled Pen. However, when initiating treatment with Aplevant 0.75mg Pre-filled Pen in combination with other anti-diabetic medicines, monitoring of blood sugar may become necessary to reduce the dose of the anti-diabetic medicine in order to lower the risk of hypoglycemia.

Can Aplevant 0.75mg Pre-filled Pen cause pancreatitis?

There are reports of acute pancreatitis due to Aplevant 0.75mg Pre-filled Pen. Patients are prompted to discontinue this medicine and contact their doctor if there is persistent severe abdominal pain, sometimes radiating to the back.

What is the significance of HbA1c test?

Your doctor may ask you to get your HbA1c tested every 3 months. This test is done to see how well you have managed your blood sugar for the past 2-3 months.

When is the best time to take Aplevant 0.75mg Pre-filled Pen?

Aplevant 0.75mg Pre-filled Pen is to be taken only once a week at any time of the day with or without food. Consult your doctor for more advice.

Can I take artificial sweeteners while taking Aplevant 0.75mg Pre-filled Pen?

No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.

What if you forget to take Aplevant Solution for Injection?

If you miss a dose of Aplevant 0.75mg Pre-filled Pen, take it as soon as you remember. If the next dose is to be taken within the next 72 hours, skip the missed dose. Do not take 2 doses of Aplevant 0.75mg Pre-filled Pen within 72 hours of each other.

Aplevant 0.75mg Pre-filled Pen Reviews

Aplevant 0.75mg Pre-filled Pen is an injectable medicine used to lower blood glucose levels in adults with type 2 diabetes. It works by helping your body produce insulin and reducing the amount of sugar your liver makes.

The dose of Aplevant 0.75mg Pre-filled Pen will depend on your condition and what other diabetes medicines you are taking. You can use it at any time of day with or without food but try to use it on the same day each week to get the most benefit. Your doctor or nurse will show you how and where to inject the medicine. Follow the instructions carefully. Do not stop taking this medicine without talking to your doctor. If you do, your blood glucose levels may increase and put you at risk of serious complications. It should be used with a proper diet and exercise to control high blood glucose. Aplevant 0.75mg Pre-filled Pen should be stored in a fridge until you need it but do not freeze it.

The most common side effects of Aplevant 0.75mg Pre-filled Pen include nausea, diarrhea, abdominal pain, and loss of appetite. It can also lead to hypoglycemia (low blood sugar level) especially if you are taking other medicines to lower blood sugar. Make sure you know how to recognize and deal with it.

Before using this medicine, talk to your doctor if you have ever had liver or kidney disease, pancreatitis, or stomach problems. Also, tell your doctor if you are taking any other medicines which may affect the way this medicine works. If you are pregnant or breastfeeding, ask your doctor if it is safe to take Aplevant 0.75mg Pre-filled Pen.

How Aplevant 0.75mg Pre-filled Pen Works

Aplevant 0.75mg Pre-filled Pen is an anti-diabetic medication. It works by increasing the release of insulin from the pancreas, decreases hormones that raise blood sugar levels, slows down digestion, and reduces appetite.

How to Use Aplevant 0.75mg Pre-filled Pen

Your doctor or nurse will guide you how to use this medicine.

Benefits of Aplevant 0.75mg Pre-filled Pen

In Treatment of Type 2 diabetes mellitus: Aplevant 0.75mg Pre-filled Pen is an injectable medicine that helps to control high blood glucose (sugar) levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Proper control of diabetes may also lessen your risk of having a heart attack or stroke. Taking Aplevant 0.75mg Pre-filled Pen regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed as it is protecting your future health.

Uses of Aplevant 0.75mg Pre-filled Pen

Treatment of Type 2 diabetes mellitus

Aplevant 0.75mg Pre-filled Pen Side Effects

Safety Tips

Liver ^{SAFE IF PRESCRIBED}

Aplevant 0.75mg Pre-filled Pen is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aplevant 0.75mg Pre-filled Pen may not be needed in these patients. Please consult your doctor.

Driving ^{CONSULT YOUR DOCTOR}

It is not known whether Aplevant 0.75mg Pre-filled Pen alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney ^{SAFE IF PRESCRIBED}

Aplevant 0.75mg Pre-filled Pen is safe to use in patients with kidney disease. No dose adjustment of Aplevant 0.75mg Pre-filled Pen is recommended.However, monitor renal function in patients with renal impairment reporting severe adverse gastrointestinal reactions. Use Aplevant 0.75mg Pre-filled Pen with caution in patients with ESRD.

Breast feeding ^{CONSULT YOUR DOCTOR}

Information regarding the use of Aplevant 0.75mg Pre-filled Pen during breastfeeding is not available. Please consult your doctor.

Alcohol ^UNSAFE

It is unsafe to consume alcohol with Aplevant 0.75mg Pre-filled Pen.

Pregnancy ^{CONSULT YOUR DOCTOR}

Aplevant 0.75mg Pre-filled Pen may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Quick Tips

Do not use Aplevant 0.75mg Pre-filled Pen if particles appear or if the solution is cloudy and/or discolored.
You can inject Aplevant 0.75mg Pre-filled Pen into the same body area each week, but try not to use the exact same spot.
Aplevant 0.75mg Pre-filled Pen may cause nausea, vomiting, diarrhea, or stomach pain, which may get better with time. Eat smaller meals, limit fatty food intake and inform your doctor if it does not go away.
Store the pen in the refrigerator. When refrigeration is not possible, you can also keep your pen at room temperature (less than 30°C) for up to 2 weeks. Do not freeze it.