Derise 100 Pre-filled Syringe
Product Info
| Prescription required | Yes |
| Marketer | Hetero Drugs Ltd |
| Active Ingredient | Darbepoetin alfa (100mcg) |
| Storage | Store in a refrigerator (2 - 8°C). Do not freeze. |
| Chemical Class | Amino Acids, Peptides Analogues |
| Habit Forming | No |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Erythropoiesis-stimulating agent (ESA) |
| User Rating | 4.5 |
| User Reviews | 735 |
FAQ
Can Derise 100 Pre-filled Syringe be used in children?
Yes, Derise 100 Pre-filled Syringe is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Derise 100 Pre-filled Syringe and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.
Other than PRCA, can there be other reasons for not responding to Derise 100 Pre-filled Syringe?
You may not respond to Derise 100 Pre-filled Syringe if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.
Is Derise 100 Pre-filled Syringe safe to use?
Derise 100 Pre-filled Syringe is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Derise 100 Pre-filled Syringe therapy. Follow all the directions strictly.
Can Derise 100 Pre-filled Syringe affect blood pressure?
Yes, Derise 100 Pre-filled Syringe can affect blood pressure. During initial therapy with Derise 100 Pre-filled Syringe, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Derise 100 Pre-filled Syringe if the blood pressure remains uncontrolled.
Who should not take Derise 100 Pre-filled Syringe?
Individuals who have cancer but have not been prescribed Derise 100 Pre-filled Syringe by the doctor should not take it. Additionally, patients with uncontrolled hypertension (high blood pressure), patients with a history of anemia called pure red cell aplasia (PRCA) that starts after treatment with Derise 100 Pre-filled Syringe or other erythropoietin medicines, and patients with a history of serious allergic reaction to this medicine should not take this medicine.
How long does it take for Derise 100 Pre-filled Syringe to start working?
You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Derise 100 Pre-filled Syringe. If you have any other concerns, consult your doctor.
What if you forget to take Derise Injection?
If you miss a dose of Derise 100 Pre-filled Syringe, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Derise 100 Pre-filled Syringe Reviews
Derise 100 Pre-filled Syringe is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.
Derise 100 Pre-filled Syringe is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.
Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).
Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash.
Before taking Derise 100 Pre-filled Syringe, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant or breastfeed, consult your doctor to make sure it is safe for you.
Derise 100 Pre-filled Syringe is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.
Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).
Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash.
Before taking Derise 100 Pre-filled Syringe, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant or breastfeed, consult your doctor to make sure it is safe for you.
How Derise 100 Pre-filled Syringe Works
Derise 100 Pre-filled Syringe is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
How to Use Derise 100 Pre-filled Syringe
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Derise 100 Pre-filled Syringe
- In Treatment of Anemia due to cancer chemotherapy: Low red blood cell count is termed as anemia. Cancer treatment with chemotherapy often causes many side effects, one of the major ones being anemia. Derise 100 Pre-filled Syringe stimulates the production of red blood cells in bone marrow and regulates the haemoglobin in the blood. This treats anemia in cancer patients receiving chemotherapy.
- In Treatment of Anemia due to chronic kidney disease: Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long span of time. CKD progresses gradually over a few years but may become permanent if left untreated. CKD can lead to anemia. Derise 100 Pre-filled Syringe can boost your levels of red blood cells and reduce the symptoms of anemia such as tiredness and weakness. Taking this injection improves the quality of life.
Uses of Derise 100 Pre-filled Syringe
- Treatment of Anemia due to chronic kidney disease
- Treatment of Anemia due to cancer chemotherapy
Derise 100 Pre-filled Syringe Side Effects
Safety Tips
Driving
SAFE
Derise 100 Pre-filled Syringe does not usually affect your ability to drive.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Derise 100 Pre-filled Syringe. Please consult your doctor.
Kidney
SAFE IF PRESCRIBED
Derise 100 Pre-filled Syringe is safe to use in patients with kidney disease. No dose adjustment of Derise 100 Pre-filled Syringe is recommended.
Breast feeding
CONSULT YOUR DOCTOR
Derise 100 Pre-filled Syringe is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy
CONSULT YOUR DOCTOR
Derise 100 Pre-filled Syringe may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Liver
CAUTION
Derise 100 Pre-filled Syringe should be used with caution in patients with liver disease. Dose adjustment of Derise 100 Pre-filled Syringe may be needed. Please consult your doctor.
Quick Tips
- Stop taking Derise 100 Pre-filled Syringe and inform your doctor if you develop shortness of breath or skin rash.
- Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells, in your blood.
- Derise 100 Pre-filled Syringe helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
- It is given as a single injection under your skin, additionally, it can be given intravenously.
References
- Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019.
- Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
- Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017].
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
- CiplaMed. Darbepoetin Alfa [Product Information]. [Last Reviewed: June 2019].
- Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001.
- Aranesp Injection (Darbepoetin alfa) [Product Information].
- Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Darbepoetin.