Toplid Dry Syrup
Product Info
| Prescription required | Yes |
| Marketer | Novogen Captab |
| Active Ingredient | Linezolid (125mg/5ml) |
| Storage | Store below 30°C |
| Chemical Class | Oxazolidinone derivative |
| Habit Forming | No |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Oxazolidinone |
| User Rating | 5.0 |
| User Reviews | 479 |
FAQ
What if I give an excess of Toplid by mistake?
Overdose may cause unwanted side effects such as low blood count, nerve damage, or loss of vision. It may even cause a life-threatening complication called lactic acidosis which shows symptoms of abdominal pain, nausea, vomiting, and generalized weakness. Rush to your child’s doctor on an immediate basis if you notice any of these symptoms.
Can I get my child vaccinated while on treatment with Toplid ?
Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.
In which disease conditions should I avoid giving Toplid to my child?
Avoid giving Toplid if your child is suffering from conditions like diabetes mellitus (risk of low glucose), hypertension, hyperthyroidism, and seizure disorder. To ensure that this medicine is not given in such conditions, tell your child’s complete medical history to the doctor before giving Toplid to your child.
My child is suffering from depression and is on antidepressant therapy. Is it safe to give Toplid along with these medicines?
No, it is not safe as it can lead to life-threatening syndrome known as serotonin syndrome which can be manifested as hypertension, increased heart rate, shaking of the body, seizures, and increased body temperature. Call your child’s doctor right away if these symptoms appear.
What food items should my child avoid while taking Toplid?
Avoid giving tyramine-containing foods like old cheese, red meat, fava or broad bean pods, soy sauce, and other soybean condiments while your child is taking Toplid. Always recheck the freshness of food before giving it to your child as it is an important concern.
Can Toplid be given for a long duration?
Prolonged use of Toplid may result in fungal or bacterial superinfection, including serious gastrointestinal infections due to inhibition of good bacteria of the gut. You must reach out to the doctor soon.
What lab tests are required for monitoring while my child is taking Toplid?
For children receiving Toplid for a longer duration, the doctor may ask for a complete blood count, basic metabolic panel, liver function test, and routine eye and nerve function assessments.
What should I do if my child shows no improvement even after taking Toplid for the prescribed duration?
Ineffective treatment with Toplid could mean that the medicine is not able to act against the infection-causing bacteria. In such a case, visit your child’s doctor who may change the medicine and prescribe an antibiotic that has a stronger impact on the infection-causing bacteria. Since some of these antibiotics are given as intravenous injections, you may have to visit the doctor to give this medicine to your child.
What if I forget to give Toplid to my child?
There is no need to panic. You can give the medicine as soon as you remember unless your child’s doctor has advised a specific regime for your child. In case of any confusion, do consult your doctor, do not double the dose to catch up.
Toplid Dry Syrup Reviews
Toplid is an antibiotic medicine. It helps cure a wide range of serious infections caused by resistant bacteria. These may include infections affecting the skin, soft tissues, bones, brain, heart, urinary tract, lungs, and blood.
Give Toplid to your child orally, preferably at a fixed time, either before or after meals. In case your child develops a stomach upset, prefer giving it with meals. Adhere to the dose, time, and way prescribed by the doctor as that depends on the type and severity of the infection, your child’s age, and body weight. If your child vomits within 30 minutes of intake, repeat the same dose but do not double dose if it's time for the next dose.
Taking this medicine may sometimes cause minor and temporary side effects. These include nausea, vomiting, diarrhea, headache, and low blood cell count. These side effects almost always subside within a few days. However, in case these side effects persist or bother your child, it would be best to consult your child’s doctor without any delay.
Your child’s doctor should be aware of your child’s complete medical history, including any previous episode of allergy, heart problem, liver impairment, blood disorder, eye disorder, and kidney malfunction. Do tell the doctor if your child is taking any other medicine too. This information is critical for dose alterations and for planning your child’s overall treatment.
How Toplid Dry Syrup Works
Toplid is an antibiotic. It stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.
How to Use Toplid Dry Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Toplid may be taken with or without food, but it is better to take it at a fixed time.Avoid Toplid with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Benefits of Toplid Dry Syrup
- In Treatment of Severe bacterial infections: Toplid works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections such as infections of lungs (pneumonia), skin, and soft tissues. This medicine usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
Uses of Toplid Dry Syrup
- Treatment of Severe bacterial infections
Toplid Dry Syrup Side Effects
Safety Tips
Liver
SAFE IF PRESCRIBED
Toplid is safe to use in patients with liver disease. No dose adjustment of Toplid is recommended.However, $med_name should be used with caution in children with severe liver disease as it can be a potential threat to liver functions although not very common.
Kidney
SAFE IF PRESCRIBED
Toplid is safe to use in patients with kidney disease. No dose adjustment of Toplid is recommended.However, Toplid must be used with caution in children with severe kidney disease. Dose modification may be required in severe kidney disease.
Quick Tips
- Discontinue Toplid and inform the doctor immediately if your child develops a rash, itchy skin, swelling of face and mouth, or difficulty in breathing.
- Only give Toplid to your child for their current infection. Never save medicine for future illnesses.
- Your child must drink plenty of water if he/she develops diarrhea as a side effect.
- Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
References
- Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 804.
- MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1537-38.
- Mayo Clinic. Drugs and Supplements: Linezolid (Oral Route).
- Linezolid [Prescribing Information]. New York, NY: Pharmacia & Upjohn Co.; 2013.
- University of Michigan: C.S. Mott Children’s Hospital. Linezolid (oral/injection).
- Linezolid [FDA Label]. New York, NY: Pharmacia & Upjohn Company; 2010.