Alkem Piroxicam Injection
Product Info
| Prescription required | Yes |
| Marketer | Alkem Laboratories Ltd |
| Active Ingredient | Piroxicam (20mg) |
| Storage | Store below 30°C |
| Chemical Class | Enolic acid Derivatives |
| Habit Forming | No |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids) |
| User Rating | 5.0 |
| User Reviews | 568 |
FAQ
Can Alkem Piroxicam lead to skin reactions?
Yes. Alkem Piroxicam is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Can I use Alkem Piroxicam if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
How long does Alkem Piroxicam work?
Alkem Piroxicam is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Can Alkem Piroxicam be used with lithium?
No. Alkem Piroxicam should not be used with lithium. Alkem Piroxicam leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Can Alkem Piroxicam be used with warfarin?
No. Alkem Piroxicam should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Is Alkem Piroxicam a narcotic?
No. Alkem Piroxicam is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
What is the difference between Alkem Piroxicam and diclofenac?
Both Alkem Piroxicam and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Alkem Piroxicam.
Can Alkem Piroxicam be used in hypertension?
No. Alkem Piroxicam is not a medication to control hypertension. It is important to note that Alkem Piroxicam decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Alkem Piroxicam.
Can Alkem Piroxicam be used with Tizanidine?
Yes, Alkem Piroxicam can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Are there any alternatives of Alkem Piroxicam?
Yes. There are alternatives to Alkem Piroxicam. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Can Alkem Piroxicam be used with calcium channel blocker?
Yes. Alkem Piroxicam can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Can Alkem Piroxicam be used in the treatment of allergy?
No. Alkem Piroxicam is not a drug to treat allergy. It is a pain killer.
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Alkem Piroxicam?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
What is the difference between Alkem Piroxicam and meloxicam?
Both Alkem Piroxicam and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Alkem Piroxicam.
Is Alkem Piroxicam effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Alkem Piroxicam as the cause of back pain can be different for different person.
Can I use Alkem Piroxicam if I am pregnant?
No. Alkem Piroxicam should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Can I use Alkem Piroxicam if I am a diabetic?
Alkem Piroxicam in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Alkem Piroxicam so taking piroxicam can lead to increased risk of renal failure by many folds.
Can you donate blood when on the medication with Alkem Piroxicam?
Yes. You can donate blood when on Alkem Piroxicam. Do inform your doctor before donating blood.
What is the difference between Alkem Piroxicam and tramadol?
Alkem Piroxicam is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Can I use Alkem Piroxicam if I have a deranged renal function?
No. Alkem Piroxicam should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Is Alkem Piroxicam a sulfa drug?
Alkem Piroxicam is a sulphur containing compound. Alkem Piroxicam can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Can Alkem Piroxicam be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Alkem Piroxicam or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Alkem Piroxicam.
Is Alkem Piroxicam a NSAID?
Yes. Alkem Piroxicam is a non-steroidal anti-inflammatory drug (NSAID).
Is Alkem Piroxicam a muscle relaxant?
No. Alkem Piroxicam is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Can I use Alkem Piroxicam for a migraine?
Alkem Piroxicam is not approved for the treatment of migraine. Research studies have shown that Alkem Piroxicam is effective in significantly decreasing the pain associated with migraine without aura.
Is Alkem Piroxicam affective in gout management?
Yes. Alkem Piroxicam can be given for the treatment of acute gout. Research studies have shown Alkem Piroxicam to be highly effective in the treatment of acute gout.
Can Alkem Piroxicam be used along with paracetamol?
Yes. Paracetamol can be used with Alkem Piroxicam as no serious side effects are known. Inform your doctor before starting any of the medication.
Can Alkem Piroxicam lead to difficulty in conception?
Yes. Alkem Piroxicam can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Why is beta cyclodextrin added to Alkem Piroxicam?
Yes. Alkem Piroxicam can be combined with beta-cyclodextrin. Research has shown that combining Alkem Piroxicam with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Can Alkem Piroxicam be used with diuretics?
No. Alkem Piroxicam should not be used with diuretics. Alkem Piroxicam reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
What is the difference between Alkem Piroxicam and nimesulide?
Both Alkem Piroxicam and nimesulide are pain killers. However, Alkem Piroxicam is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Can I use Alkem Piroxicam if I have peptic ulcer disease?
No. Alkem Piroxicam is contraindicated in cases of active peptic ulcer disease. Alkem Piroxicam is known to cause gastric ulceration and bleeding.
Can Alkem Piroxicam be used along with dexamethasone?
No. Alkem Piroxicam should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
What is the difference between Alkem Piroxicam and naproxen?
Both Alkem Piroxicam and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Alkem Piroxicam.
What is the difference between Alkem Piroxicam and ketoprofen?
Both Alkem Piroxicam and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Alkem Piroxicam. Ketoprofen gel also showed excellent tolerability.
Can Alkem Piroxicam be used with methocarbamol?
Yes. Methocarbamol can be used with Alkem Piroxicam as no serious side effects are known. Inform your doctor before starting any of the medication.
Can Alkem Piroxicam be used along with Losartan?
No. Alkem Piroxicam should not be combined with Losartan. It is important to note that Alkem Piroxicam decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Alkem Piroxicam.
Can you get high by using Alkem Piroxicam?
No. Alkem Piroxicam is not known to cause high. It is a non-narcotic painkiller.
What are the serious side effects of Alkem Piroxicam?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
What are the contraindications for Alkem Piroxicam?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Are Alkem Piroxicam and aspirin same?
No. Alkem Piroxicam and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Can Alkem Piroxicam be used to treat menstrual cramp?
Alkem Piroxicam is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Is Alkem Piroxicam a blood thinner?
No. Alkem Piroxicam is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
What increases the chances of getting a gastric ulcer when I am already taking Alkem Piroxicam?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Can Alkem Piroxicam be used with Lisinopril?
No. Alkem Piroxicam should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Alkem Piroxicam.
What if you forget to take Alkem Piroxicam?
If you miss a dose of Alkem Piroxicam, consult your doctor.
Alkem Piroxicam Injection Reviews
Alkem Piroxicam is a pain-relieving medicine. It is used in the treatment of moderate to severe pain. It helps to relieve pain and swelling of various conditions related to joints and muscles. It is usually given in cases where oral administration is unsuitable.
Alkem Piroxicam is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), vomiting, stomach pain, indigestion, diarrhea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
How Alkem Piroxicam Injection Works
Alkem Piroxicam is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
How to Use Alkem Piroxicam Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Alkem Piroxicam Injection
- In Pain relief: Alkem Piroxicam is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Uses of Alkem Piroxicam Injection
- Pain relief
Alkem Piroxicam Injection Side Effects
Safety Tips
Kidney
CAUTION
Alkem Piroxicam should be used with caution in patients with severe kidney disease. Dose adjustment of Alkem Piroxicam may be needed. Please consult your doctor.
Liver
CAUTION
Alkem Piroxicam should be used with caution in patients with liver disease. Dose adjustment of Alkem Piroxicam may be needed. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Alkem Piroxicam is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Driving
UNSAFE
Alkem Piroxicam may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Alcohol
CAUTION
Caution is advised when consuming alcohol with Alkem Piroxicam. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Alkem Piroxicam is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Quick Tips
- Alkem Piroxicam helps relieve pain and swelling of various joints and muscles.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
References
- Piroxicam [Drug Label]. Metro Manila, Philippines: Pfizer, Inc.; 2022.
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
- Central Drugs Standard Control Organisation (CDSCO).
- ScienceDirect. Piroxicam.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
- Pubchem. Piroxicam.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.