Amphocil 100mg Injection

Product Info

FAQ

Is Amphocil 100mg testing dose needed?

Yes, administration of Amphocil 100mg is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity

How is Amphocil 100mg administered?

Amphocil 100mg is either administered as intravenous injection or infusion by a registered medical professional only

Is Amphocil 100mg an antibiotic?

Yes, Amphocil 100mg is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)

What is Amphocil 100mg liposomal?

Liposomal Amphocil 100mg is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphocil 100mg can substantially improves drug safety especially nephrotoxicity associated with the drug

Is Amphocil 100mg light sensitive?

Amphocil 100mg is not light sensitive

How does Amphocil 100mg cause nephrotoxicity and hyperkalemia?

Amphocil 100mg can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.

Is Amphocil 100mg fungistatic or fungicidal?

Amphocil 100mg is fungicidal in nature, it acts by killing the fungus

What if you forget to take Amphocil Injection?

If you miss a dose of Amphocil 100mg, please consult your doctor.

Amphocil 100mg Injection Reviews

How Amphocil 100mg Injection Works

How to Use Amphocil 100mg Injection

Benefits of Amphocil 100mg Injection

• In Severe fungal infections: Amphocil 100mg works by killing the fungi which can cause serious infections. It is given by a doctor or nurse and should not be self-administered. It usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all the fungi and yeast causing the infection are killed and do not become resistant.
• In Kala-azar: Kala azar is a disease caused by leishmania parasites mainly by the bite of infected sandflies. Amphocil 100mg helps to kill the infection causing parasites and helps to treat the infection. This medicine is given by a doctor or nurse and should not be self-administered. It usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all the parasites are killed and do not become resistant.

Uses of Amphocil 100mg Injection

• Severe fungal infections
• Kala-azar

Amphocil 100mg Injection Side Effects

• Nephrocalcinosis
• Nausea
• Skin rash
• Injection site reactions (pain, swelling, redness)
• Decreased potassium level in blood
• Decreased appetite
• Decreased magnesium level in blood
• Headache
• Hypotension (low blood pressure)
• Increased creatinine level in blood
• Abnormal renal function tests
• Chills
• Anemia (low number of red blood cells)
• Renal tubular acidosis
• Abnormal liver function tests
• Vomiting
• Diarrhea

Safety Tips

Quick Tips

• It is usually given as an injection over 1-2 hours under the supervision of a medical professional.
• Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
• Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 
• Amphocil 100mg can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
• Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.

References

1. Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 836-38.
2. Amphotericin B. San Dimas, California: Gilead Sciences, Inc.; 2000.
3. Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1424.
4. Central Drugs Standard Control Organisation (CDSCO).
5. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1571-75.
6. Medsacpe. Amphotericin.
7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004; 80(5):4-6.
8. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 68-69.

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