Bevnexxa 100mg Injection
Product Info
| Prescription required | Yes |
| Marketer | Celon Laboratories Ltd |
| Active Ingredient | Bevacizumab (100mg) |
| Storage | Store in a refrigerator (2 - 8°C). Do not freeze. |
| Chemical Class | Monoclonal antibody (mAb) |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Vascular endothelial growth factor (VEGF) inhibitor |
| User Rating | 4.2 |
| User Reviews | 737 |
FAQ
How long can I take Bevnexxa 100mg for?
You keep taking Bevnexxa 100mg as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking Bevnexxa 100mg. If your cancer progresses during this initial treatment, talk to your doctor if a different chemotherapy may be an option.
Does a person taking Bevnexxa 100mg still need chemotherapy?
Chemotherapy is still needed along with taking Bevnexxa 100mg. It makes chemotherapy work better.
What kinds of cancer can Bevnexxa 100mg be used for ?
Bevnexxa 100mg is approved for the treatment of cancer of the colon or rectum that has spread to other parts of the body. It must be given along with chemotherapy. Other types of cancers that it helps with includes certain types of lung cancer, kidney cancer, ovarian cancer, cervical cancer, and glioblastoma (a type of brain tumor).
How Bevnexxa 100mg works differently from chemotherapy?
Chemotherapy attacks fast-growing cells, like cancer cells. In contrast, the purpose of Bevnexxa 100mg is to prevent the growth of new blood vessels that feed tumors. This causes the tumour to shrink, or to stop growing.
How is Bevnexxa 100mg given?
Bevnexxa 100mg is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. Your doctor will decide your dose and duration and will monitor you for signs of an infusion reaction.
What if you forget to take Bevnexxa Injection?
If you miss a dose of Bevnexxa 100mg, please consult your doctor.
Bevnexxa 100mg Injection Reviews
Bevnexxa 100mg is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing.
Bevnexxa 100mg is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Bevnexxa 100mg as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication.
The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
Bevnexxa 100mg is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Bevnexxa 100mg as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication.
The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
How Bevnexxa 100mg Injection Works
Bevnexxa 100mg is a anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the formation of blood vessels that bring oxygen and nutrients to cancerous cells.
How to Use Bevnexxa 100mg Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Uses of Bevnexxa 100mg Injection
- Ovarian cancer
- Non-small cell lung cancer
- Cervical cancer
- Brain tumor
- Cancer of colon and rectum
- Kidney cancer
Bevnexxa 100mg Injection Side Effects
- Abscess
- Decreased appetite
- Decreased white blood cell count (lymphocytes)
- Thromboembolism
- Mucosal inflammation
- Nosebleeds
- Ovarian failure
- Electrolyte imbalance
- Exfoliative dermatitis
- Peripheral sensory neuropathy
- Wound healing complications
- Hypersensitivity
- Protein in urine
- High blood pressure
- Rectovaginal fistula
- Cellulitis
- Breathlessness
- Low blood platelets
Safety Tips
Driving
UNSAFE
Bevnexxa 100mg may cause side effects which could affect your ability to drive.Sleepiness and fainting have been reported with Bevnexxa 100mg and this may impair your ability to drive.
Liver
SAFE IF PRESCRIBED
Bevnexxa 100mg is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Bevnexxa 100mg may not be needed in these patients. Please consult your doctor.
Kidney
SAFE IF PRESCRIBED
Bevnexxa 100mg is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Bevnexxa 100mg may not be needed in these patients. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Bevnexxa 100mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bevnexxa 100mg. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Bevnexxa 100mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Quick Tips
- Bevnexxa 100mg is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.
- Bevnexxa 100mg is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.
- It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
- It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
- It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
- Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Bevnexxa 100mg.
- Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Bevnexxa 100mg.
- Bevnexxa 100mg is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.
- It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
- Bevnexxa 100mg is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.
References
- Bevacizumab. South San Francisco, California: Genentech, Inc.; 2004 [revised Sep. 2011].
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Bevacizumab. [Updated 2019 Jul 20].
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1739-40.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 142-43.