Bondronat 6mg Injection


Product Info

Prescription required Yes
Marketer Roche Products India Pvt Ltd
Active Ingredient Ibandronic Acid (6mg)
Storage Store below 30°C
Chemical ClassBisphosphonate Derivative
Habit FormingNo
Therapeutic ClassPAIN ANALGESICS
Action ClassBone resorption inhibitor -Bisphosphonates
User Rating4.4
User Reviews420

FAQ

Question
Is Bondronat 6mg safe?
Bondronat 6mg is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Answer

Question
How is Bondronat 6mg administered?
Bondronat 6mg should be administered by a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Bondronat 6mg.
Answer

Question
How does Bondronat 6mg work?
Bondronat 6mg works by increasing the density of the bones which helps prevent osteoporosis. Along with that, it helps to treat high calcium levels in the blood caused due to secondary bone cancer. It is also helpful in treating metastasis of bone which is caused due to breast cancer.
Answer

Question
How long should I take Bondronat 6mg?
Bondronat 6mg should be taken in the dose and duration advised by your doctor. Usually Bondronat 6mg is prescribed for at least 6 months before it has the maximum effect on your bones. However, your doctor may continue your treatment for as long as Bondronat 6mg is working well for you.
Answer

Question
What is Bondronat 6mg? What is it used for?
Bondronat 6mg belongs to a class of medicines called bisphosphonates that prevents abnormal breakdown of the bones. Bondronat 6mg is used to prevent and treat osteoporosis and fractures in people with metastatic cancer (a cancer which spreads to newer areas of the body). It may also be used to treat hypercalcemia (elevated blood calcium levels).
Answer

Question
What other lifestyle changes should I make?
To get maximum benefit from Bondronat 6mg, there are certain lifestyle changes that you must adhere to. Include some calcium or Vitamin D rich foods for bone strength. Try to spend more time in sunlight to get natural vitamin D. Quit smoking and reduce alcohol consumption as they may harm your bones. You can take up an exercise regime such as walking and low-impact aerobics as they are good for your bones. Similarly, you can try strength-training exercises where you use your own body weight which in turn improve bone health.
Answer
Question
What if you forget to take Bondronat Injection?
If you miss a dose of Bondronat 6mg, skip it and continue with your normal schedule. Do not double the dose.\n
Answer

Bondronat 6mg Injection Reviews

Bondronat 6mg is used to treat high levels of a mineral called calcium in people who have cancer. It is also used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or the use of steroids. Using this medicine can reduce your risk of breaking bones.

Bondronat 6mg is given by a doctor or nurse. You will not need to do this yourself. How much you are given, and how often, will be decided by your doctor. It may just be a single injection but if you are being treated for bone problems caused by the spread of cancer you may need regular injections. Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated. It may take several days to get the full benefit of this drug. Bondronat 6mg is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.

The most common side effects include headache, musculoskeletal (bone, muscle, or joint) pain, indigestion, heartburn, and diarrhea. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Bondronat 6mg can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills), or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away.

You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also, let your doctor know what other drugs you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.

How Bondronat 6mg Injection Works

Bondronat 6mg is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.

How to Use Bondronat 6mg Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Bondronat 6mg Injection

  • In Osteoporosis: Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Bondronat 6mg is a type of medicine called a bisphosphonate. It slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is usually given once every year to treat osteoporosis and every two years to prevent it.You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D, and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.
  • In Hypercalcemia: Calcium is a mineral found in different places in your body and has many functions including bone growth. Most of your calcium should be in your bones. When you have more calcium in your blood than normal it is called hypercalcaemia (high blood calcium levels). It is a serious condition and affects a large number of people with cancer. Bondronat 6mg is a type of medicine called a bisphosphonate. It reduces the amount of calcium in your blood by slowing down the rate at which bone is broken down in your body. This medicine is normally only given once by injection to treat hypercalcaemia, but you may need additional doses. Make sure you attend all appointments with your doctor.Being immobile makes hypercalcaemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.

Uses of Bondronat 6mg Injection

  • Hypercalcemia
  • Osteoporosis

Bondronat 6mg Injection Side Effects

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Safety Tips

Pregnancy  CONSULT YOUR DOCTOR
Bondronat 6mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Driving  SAFE
Bondronat 6mg does not usually affect your ability to drive.
Liver  SAFE IF PRESCRIBED
Bondronat 6mg is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Bondronat 6mg may not be needed in these patients. Please consult your doctor.
Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Bondronat 6mg during breastfeeding is not available. Please consult your doctor.
Kidney  SAFE IF PRESCRIBED
Bondronat 6mg is safe to use in patients with kidney disease. No dose adjustment of Bondronat 6mg is recommended.However, the use of Bondronat 6mg is not recommended in patients with severe renal impairment.
Alcohol  CAUTION
Caution is advised when consuming alcohol with Bondronat 6mg. Please consult your doctor.

Quick Tips

  • Your doctor will monitor your response to Bondronat 6mg by testing your bone mineral density (BMD). This is usually done every 1-3 years.
  • It is given by injection into a vein, usually over 15-30 seconds or as directed by your doctor.
  • It can lower the level of calcium in the blood. Take calcium and vitamin D supplements as suggested by your doctor.
  • Drink plenty of fluids to prevent dehydration and kidney damage.
  • Do not take it if you are pregnant.
  • You may develop fever or flu-like symptoms, such as chills, tiredness, and weakness. These are usually temporary and should go away after a few days. You may take a pain reliever/fever reducer to prevent or treat these symptoms.
  • It may cause a rare condition called osteonecrosis of the jaw. Have regular dental check-ups and inform your doctor if you develop sudden pain in your jaw.

References

  1. Ibandronate Sodium Injection [Prescribing Information]. Tainan City, Taiwan: Nang Kuang Pharmaceutical Co., Ltd.; 2022.
  2. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Ibandronate. [Updated 2021 Apr 19].
  3. Central Drugs Standard Control Organisation. Ibandronic Acid.
  4. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 630.
  5. Central Drugs Standard Control Organisation (CDSCO).
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
  7. Ibandronic acid bondronat [Product Information]. Akshar Pharma.
  8. Vinetz JM, Clain J, Bounkeua V, Eastman RT, et al. Chemotherapy of Malaria. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1402-405.
  9. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 669-71.

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