Bonspri Solution for Injection
Product Info
| Prescription required | Yes |
| Marketer | Novartis India Ltd |
| Active Ingredient | Ofatumumab (20mg/0.4ml) |
| Chemical Class | Monoclonal antibody (mAb) |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | CD 20 Inhibitor |
| User Rating | 4.9 |
| User Reviews | 317 |
FAQ
Bonspri Solution for Injection Reviews
Bonspri Solution for is used in the treatment of blood cancer (chronic lymphocytic leukemia). It binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body's immune system.
Bonspri Solution for is given as an injection into the veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, diarrhea, breathlessness, cough, etc. Let your doctor know if any of these side effects bothers you pr persists for a longer duration of time. Regular blood tests are required to check your blood cells along with heart, liver and kidney function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Bonspri Solution for is given as an injection into the veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, diarrhea, breathlessness, cough, etc. Let your doctor know if any of these side effects bothers you pr persists for a longer duration of time. Regular blood tests are required to check your blood cells along with heart, liver and kidney function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
How Bonspri Solution for Injection Works
Bonspri Solution for is a monoclonal antibody. It specifically binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body's immune system.
How to Use Bonspri Solution for Injection
Your doctor or nurse will guide you how to use this medicine.
Benefits of Bonspri Solution for Injection
- In Blood cancer (Chronic lymphocytic leukemia): Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Bonspri Solution for kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Uses of Bonspri Solution for Injection
- Blood cancer (Chronic lymphocytic leukemia)
Bonspri Solution for Injection Side Effects
Safety Tips
Kidney
SAFE IF PRESCRIBED
Bonspri Solution for is safe to use in patients with kidney disease. No dose adjustment of Bonspri Solution for is recommended.
Pregnancy
CONSULT YOUR DOCTOR
Bonspri Solution for may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bonspri Solution for. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Bonspri Solution for is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Bonspri Solution for alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Liver
UNSAFE
Bonspri Solution for is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Quick Tips
- Inform your doctor if you experience fever, chills, rash, dizziness and shortness of breath during the treatment.
- Your doctor may get regular blood tests done to monitor your blood cell count (CBC), liver and kidney function.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Do not skip any dose and complete the course as suggested by your doctor.
- Bonspri Solution for is given as an IV infusion under the supervision of a doctor.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1011.
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1747-48.
- Ofatumumab. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Jan. 2016].