Cafirate Injection
Product Info
| Prescription required | Yes |
| Marketer | Sun Pharmaceutical Industries Ltd |
| Active Ingredient | Caffeine (20mg/ml) |
| Storage | Store below 30°C |
| Chemical Class | Xanthine Derivative |
| Habit Forming | No |
| Therapeutic Class | CARDIAC |
| Action Class | Adenosine receptor (A1 & A2) antagonist |
| User Rating | 4.9 |
| User Reviews | 364 |
FAQ
Cafirate Injection Reviews
Cafirate is a prescription medicine used in the treatment of apnea (a disorder in which breathing repeatedly stops and starts) of prematurity. It facilitates normal breathing and reduces interrupted breathing in premature newborns.
Cafirate is given under the supervision of healthcare professionals. Remember, if you are breastfeeding while your infant is treated with this medicine, then do not drink coffee or take any other high caffeine product as this passes into breast milk.
Some common side effects of this medicine include mild delirium, insomnia, frequent urge to urinate, dehydration, tachycardia, and fever. Consult your doctor if these do not go away or persist for a longer duration. They may be able to suggest ways to prevent or reduce the side effects.
Cafirate is given under the supervision of healthcare professionals. Remember, if you are breastfeeding while your infant is treated with this medicine, then do not drink coffee or take any other high caffeine product as this passes into breast milk.
Some common side effects of this medicine include mild delirium, insomnia, frequent urge to urinate, dehydration, tachycardia, and fever. Consult your doctor if these do not go away or persist for a longer duration. They may be able to suggest ways to prevent or reduce the side effects.
How Cafirate Injection Works
Cafirate is a stimulant. It works by blocking the action of certain natural substances (adenosine and phosphodiesterase) leading to stimulation of the brain and respiratory system in premature newborns. This reduces the number of episodes of interrupted breathing and helps the newborns breathe on their own.
How to Use Cafirate Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Cafirate Injection
- In Apnea of prematurity: In a premature baby, the part of the brain that controls breathing is not mature enough for nonstop breathing. This causes large bursts of breath followed by periods of shallow breathing or stopped breathing. This is called apnea or breathing trouble of prematurity. Cafirate helps to stimulate those areas of the brain that control breathing and normalise it. It is given as an injection by a doctor or nurse.
Uses of Cafirate Injection
- Apnea of prematurity
Cafirate Injection Side Effects
Safety Tips
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Cafirate in patients with kidney disease. Please consult your doctor.
Alcohol
UNSAFE
It is unsafe to consume alcohol with Cafirate.
Driving
UNSAFE
Cafirate may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Pregnancy
CONSULT YOUR DOCTOR
Cafirate may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CAUTION
Cafirate should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Cafirate in patients with liver disease. Please consult your doctor.
Quick Tips
- It is given as an injection (drip) by your doctor or nurse.
- Cafirate helps in the treatment of interrupted breathing in premature babies.
- If you are breast-feeding while your infant is treated with Cafirate, do not drink coffee or take any other high caffeine product as caffeine passes into breast milk.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 179-83.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Caffeine. [Updated 2019 Jun 30].
- O’Brien CP. Drug Addiction. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 663.
- Tulane University: School of Medicine. Caffeine.
- Drugs.com. Caffeine Pregnancy and Breastfeeding Warnings.