Cresp 100 Injection

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Dr Reddy's Laboratories Ltd
Active Ingredient	Darbepoetin alfa (100mcg)
Storage	Store in a refrigerator (2 - 8°C). Do not freeze.
Chemical Class	Amino Acids, Peptides Analogues
Habit Forming	No
Therapeutic Class	BLOOD RELATED
Action Class	Erythropoiesis-stimulating agent (ESA)
User Rating	4.7
User Reviews	678

FAQ

Can Cresp 100 affect blood pressure?

Yes, Cresp 100 can affect blood pressure. During initial therapy with Cresp 100, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Cresp 100 if the blood pressure remains uncontrolled.

Who should not take Cresp 100?

Individuals who have cancer but have not been prescribed Cresp 100 by the doctor should not take it. Additionally, patients with uncontrolled hypertension (high blood pressure), patients with a history of anemia called pure red cell aplasia (PRCA) that starts after treatment with Cresp 100 or other erythropoietin medicines, and patients with a history of serious allergic reaction to this medicine should not take this medicine.

How long does it take for Cresp 100 to start working?

You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Cresp 100. If you have any other concerns, consult your doctor.

Other than PRCA, can there be other reasons for not responding to Cresp 100?

You may not respond to Cresp 100 if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.

Can Cresp 100 be used in children?

Yes, Cresp 100 is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Cresp 100 and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.

Is Cresp 100 safe to use?

Cresp 100 is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Cresp 100 therapy. Follow all the directions strictly.

What if you forget to take Cresp Injection?

If you miss a dose of Cresp 100, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Cresp 100 Injection Reviews

Cresp 100 is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.

Cresp 100 is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.

Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).

Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash.

Before taking Cresp 100, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant or breastfeed, consult your doctor to make sure it is safe for you.

How Cresp 100 Injection Works

Cresp 100 is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

How to Use Cresp 100 Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Cresp 100 Injection

In Treatment of Anemia due to chronic kidney disease: Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long span of time. CKD progresses gradually over a few years but may become permanent if left untreated. CKD can lead to anemia. Cresp 100 can boost your levels of red blood cells and reduce the symptoms of anemia such as tiredness and weakness. Taking this injection improves the quality of life.
In Treatment of Anemia due to cancer chemotherapy: Low red blood cell count is termed as anemia. Cancer treatment with chemotherapy often causes many side effects, one of the major ones being anemia. Cresp 100 stimulates the production of red blood cells in bone marrow and regulates the haemoglobin in the blood. This treats anemia in cancer patients receiving chemotherapy.

Uses of Cresp 100 Injection

Treatment of Anemia due to cancer chemotherapy
Treatment of Anemia due to chronic kidney disease

Cresp 100 Injection Side Effects

Safety Tips

Kidney ^{SAFE IF PRESCRIBED}

Cresp 100 is safe to use in patients with kidney disease. No dose adjustment of Cresp 100 is recommended.

Pregnancy ^{CONSULT YOUR DOCTOR}

Cresp 100 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Alcohol ^{CONSULT YOUR DOCTOR}

It is not known whether it is safe to consume alcohol with Cresp 100. Please consult your doctor.

Liver ^CAUTION

Cresp 100 should be used with caution in patients with liver disease. Dose adjustment of Cresp 100 may be needed. Please consult your doctor.

Driving ^SAFE

Cresp 100 does not usually affect your ability to drive.

Breast feeding ^{CONSULT YOUR DOCTOR}

Cresp 100 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Quick Tips

Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells, in your blood.
It is given as a single injection under your skin, additionally, it can be given intravenously.
Cresp 100 helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
Stop taking Cresp 100 and inform your doctor if you develop shortness of breath or skin rash.

References

Aranesp Injection (Darbepoetin alfa) [Product Information].
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019.
Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001.
CiplaMed. Darbepoetin Alfa [Product Information]. [Last Reviewed: June 2019].
Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017].
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Darbepoetin.
Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.