Dacarex 100mg Injection


Product Info

Prescription required Yes
Marketer Alkem Laboratories Ltd
Active Ingredient Dacarbazine (100mg)
Storage Store in a refrigerator (2 - 8°C). Do not freeze.
Chemical ClassTriazene Derivative
Habit FormingNo
Therapeutic ClassANTI NEOPLASTICS
Action ClassAlkylating agent
User Rating4.9
User Reviews650

FAQ

Question
What is Dacarex 100mg used for?
Dacarex 100mg is used to treat skin cancer that has spread to other parts of the body (malignant melanoma), cancer of the white blood cell (Hodgkin's lymphoma) and advanced adult soft tissue sarcomas (cancer of soft tissues such as muscles, tendons, fat, and blood vessels).
Answer

Question
How effective is Dacarex 100mg?
Dacarex 100mg is effective if taken at recommended dosage and duration as advised by your doctor.
Answer

Question
How is Dacarex 100mg administered?
Dacarex 100mg is administered as infusion or injection. Absorption by mouth is slow and varies, therefore, intravenous (given through vein) infusion or injection administration is preferred.
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Question
Does Dacarex 100mg cause hair loss?
Yes, hair loss is a common side effect of Dacarex 100mg.
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Question
Is Dacarex 100mg a vesicant?
Dacarex 100mg is a potent vesicant (it is corrosive), and it should be carefully administered to avoid the risk of extravasation (leaking into the tissues).
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Question
What if you forget to take Dacarex Injection?
If you miss a dose of Dacarex 100mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Dacarex 100mg Injection Reviews

Dacarex 100mg is used in the treatment of cancers of lymphatic system and malignant melanoma (a type of skin cancer). It may be also used to treat other conditions, as determined by the doctor.

Dacarex 100mg is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, and decreased white blood cell count, and injection site pain,. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

How Dacarex 100mg Injection Works

Dacarex 100mg is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

How to Use Dacarex 100mg Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Dacarex 100mg Injection

  • In Malignant melanoma: Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Dacarex 100mg sticks to the genetic code, called DNA,of the cancer cells and kills them . It also prevents their growth and further spread. This helps to treat the cancer.
  • In Hodgkin’s disease: Hodgkin’s disease is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get rid of waste and fight infections. Dacarex 100mg kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully.

Uses of Dacarex 100mg Injection

  • Malignant melanoma
  • Hodgkin’s disease

Dacarex 100mg Injection Side Effects

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Safety Tips

Breast feeding  CONSULT YOUR DOCTOR
Dacarex 100mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Liver  CAUTION
Dacarex 100mg should be used with caution in patients with liver disease. Dose adjustment of Dacarex 100mg may be needed. Please consult your doctor.
Driving  UNSAFE
Dacarex 100mg may cause side effects which could affect your ability to drive.Dacarex 100mg may influence the ability to drive because of its central nervous system side effects.
Pregnancy  CONSULT YOUR DOCTOR
Dacarex 100mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Kidney  CAUTION
Dacarex 100mg should be used with caution in patients with kidney disease. Dose adjustment of Dacarex 100mg may be needed. Please consult your doctor.
Alcohol  CAUTION
Caution is advised when consuming alcohol with Dacarex 100mg. Please consult your doctor.

Quick Tips

  • Dacarex 100mg is given as an injection into veins under the supervision of a doctor. 

References

  1. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dacarbazine. [Updated 2018 Dec 3].
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942.
  3. Drugs.com. Dacarbazine Pregnancy and Breastfeeding Warnings.
  4. Dacarbazine citrate. Wedel, Germany: medac GmbH; 1997 [revised Jan. 2017].
  5. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1686-87.
  6. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.

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