Dobunex 250mg Injection

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Vhb Life Sciences Inc
Active Ingredient	Dobutamine (250mg)
Storage	Store below 30°C
Chemical Class	Catecholamine Derivative
Habit Forming	No
Therapeutic Class	CARDIAC
Action Class	Sympathomimetics agonist-Inotropes
User Rating	4.5
User Reviews	390

FAQ

What if you forget to take Dobunex Injection?

If you miss a dose of Dobunex 250mg, please consult your doctor.\n

Dobunex 250mg Injection Reviews

Dobunex 250mg is a medicine used for short-term treatment of cardiac decompensation (low blood pressure due to poorly functioning heart) due to disease like heart failure, cardiogenic shock, or heart attack. It increases the blood pressure by increasing the pumping capacity of the heart.

Dobunex 250mg is also used while performing stress echocardiography evaluation of the heart. It is administered under the supervision of a doctor as it requires continuous blood pressure monitoring. The dose has to be individually adjusted as per the patient's response to therapy. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure.

It may cause side effects like high blood pressure and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly.

How Dobunex 250mg Injection Works

Dobunex 250mg is a sympathomimetic agonist. It works by activating the receptors in the heart. This makes the heart pump blood with more strength and force and increases its pumping capacity in conditions such as heart failure.

How to Use Dobunex 250mg Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Dobunex 250mg Injection

In Heart failure: Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Dobunex 250mg makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Follow your doctor’s instructions carefully to get maximum benefit.
In Low blood pressure: Dobunex 250mg is used to normalise decreased blood pressure (hypotension) which may occur all of a sudden during an operation, severe infection (sepsis) or due to an emergency condition (cardiac arrest). This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.

Uses of Dobunex 250mg Injection

Low blood pressure
Heart failure

Dobunex 250mg Injection Side Effects

Safety Tips

Alcohol ^{CONSULT YOUR DOCTOR}

It is not known whether it is safe to consume alcohol with Dobunex 250mg. Please consult your doctor.

Pregnancy ^{SAFE IF PRESCRIBED}

Dobunex 250mg is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving ^UNSAFE

Dobunex 250mg may cause side effects which could affect your ability to drive.

Kidney ^{SAFE IF PRESCRIBED}

Dobunex 250mg is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Dobunex 250mg may not be needed in these patients. Please consult your doctor.

Breast feeding ^{SAFE IF PRESCRIBED}

Dobunex 250mg is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Liver ^{CONSULT YOUR DOCTOR}

There is limited information available on the use of Dobunex 250mg in patients with liver disease. Please consult your doctor.

Quick Tips

Your doctor may perform regular blood tests to monitor the level of sodium and potassium in the blood.
It is given into the vein as a drip by a healthcare professional.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

References

Teerlink JR, Sliwa K, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 177-81.
Central Drugs Standard Control Organisation (CDSCO). Dobutamine.
Katzung BG, Parmley WW. Drugs Used in Heart Failure. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 216-217.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dobutamine. [Updated 2018 Dec 3].
Dobutamine hydrochloride. Gloucester, UK: Hameln Pharmaceuticals Ltd.; 1994 [revised 08 Aug. 2018].
Maron BA, Rocco TP. Pharmacotherapy of Congestive Heart Failure. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 804-805.
Dobutamine. Lake Forest, Illinois: Hospira, Inc.; 2016.
Dobutamine. Hameln, Germany: Siegfried Hameln GmbH; 2018.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 421.