Es LC Injection

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Esperer Bioresearch Pvt Ltd
Active Ingredient	Calcium Leucovorin (50mg)
Salt Synonyms	Calcium folinate
Storage	Store in a refrigerator (2 - 8°C). Do not freeze.
Chemical Class	Glutamic acid Derivatives
Habit Forming	No
Therapeutic Class	BLOOD RELATED
Action Class	Cytoprotective agents- methotrexate
User Rating	4.8
User Reviews	486

FAQ

What is megaloblastic anemia?

Anemia is a blood disorder in which the number of red blood cells (RBCs) that carry oxygen is lower than usual. As a result, your tissues and organs don’t get enough oxygen. Megaloblastic anemia is a form of anemia characterized by very large red blood cells and a decrease in the number of those cells. Usually, megaloblastic anemia is due to vitamin B12 or folic acid deficiency. How long does it take for Es LC to work?

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Es LC?

Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

How long does it take for Es LC to work?

Es LC starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What are some of the laboratory tests conducted before or during the treatment with Es LC?

Your doctor will prescribe blood tests to check your levels of serum methotrexate concentration (in case of methotrexate chemotherapy or overdose) to determine the optimal dose and duration of treatment with Es LC. You will also be prescribed a complete blood count to monitor the number of red blood cells (in case of megaloblastic anemia). Along with this, your calcium levels will also be monitored in order to prevent hypercalcemia (excess calcium) since Es LC contains calcium.

What is Es LC used for?

Es LC is used to prevent harmful effects of methotrexate (cancer chemotherapy medication) when methotrexate is used to treat certain types of cancer. Es LC is also used to treat people who have accidentally received an overdose of methotrexate or similar medications. It is also used for the treatment of megaloblastic anemia due to folic acid deficiency and when oral therapy is not feasible.

What if you forget to take Es LC?

If you miss a dose of Es LC, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Es LC Injection Reviews

Es LC is used to prevent the harmful effects of methotrexate (anticancer medicine). It is also used to treat overdose of methotrexate.

Es LC is given as a slow injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects.

Injection site reactions (pain, swelling, redness) are common side effects of this medicine. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells and serum methotrexate concentration in blood.

Before taking it, tell your doctor if have seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using, especially phenytoin for your seizures. To make sure it is safe for you, let your doctor know if you are pregnant or breastfeeding before taking this medicine.

How Es LC Injection Works

Es LC is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.

How to Use Es LC Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Es LC Injection

In Prevention of Harmful effects of methotrexate: Es LC helps protect the body cells against the harmful effects of methotrexate, an anti-cancer medicine. It is a form of vitamin B that is given after 24 hours of methotrexate administration. This makes sure that methotrexate has achieved its anti-cancer effects and also, Es LC will prevent the other side effects such as anemia.

Uses of Es LC Injection

Prevention of Harmful effects of methotrexate

Es LC Injection Side Effects

Injection site reactions (pain, swelling, redness)

Safety Tips

Breast feeding ^{CONSULT YOUR DOCTOR}

Information regarding the use of Es LC during breastfeeding is not available. Please consult your doctor.

Driving ^SAFE

Es LC does not usually affect your ability to drive.

Kidney ^{CONSULT YOUR DOCTOR}

There is limited information available on the use of Es LC in patients with kidney disease. Please consult your doctor.

Alcohol ^{CONSULT YOUR DOCTOR}

It is not known whether it is safe to consume alcohol with Es LC. Please consult your doctor.

Liver ^{CONSULT YOUR DOCTOR}

There is limited information available on the use of Es LC in patients with liver disease. Please consult your doctor.

Pregnancy ^{CONSULT YOUR DOCTOR}

Es LC may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Quick Tips

You have been prescribed Es LC to reduce the side effects of the medicine methotrexate.
Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate.
Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Es LC may counteract the antiepileptic effects.