Fludara Injection
Product Info
| Prescription required | Yes |
| Marketer | Sanofi India Ltd |
| Active Ingredient | Fludarabine (50mg) |
| Storage | Store in a refrigerator (2 - 8°C). Do not freeze. |
| Chemical Class | Purine nucleosides Analog |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| User Rating | 4.7 |
| User Reviews | 565 |
FAQ
Fludara Injection Reviews
Fludara is used in the treatment of blood cancer called chronic lymphocytic leukemia (CLL). It may be used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Fludara is given as infusion into veins under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, weakness, fever, and cough. This medicine may reduce the number of blood cells (decrease white blood cells and red blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Fludara is given as infusion into veins under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, weakness, fever, and cough. This medicine may reduce the number of blood cells (decrease white blood cells and red blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
How Fludara Injection Works
Fludara is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in blood. This slows the growth of cancer cells and eventually kills them.
How to Use Fludara Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Fludara Injection
- In Blood cancer (Chronic lymphocytic leukemia): Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Fludara kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Uses of Fludara Injection
- Blood cancer (Chronic lymphocytic leukemia)
Fludara Injection Side Effects
Safety Tips
Breast feeding
UNSAFE
Fludara is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy
CONSULT YOUR DOCTOR
Fludara is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Kidney
CAUTION
Fludara should be used with caution in patients with kidney disease. Dose adjustment of Fludara may be needed. Please consult your doctor.Use of Fludara is not recommended in patients with severe kidney disease.
Driving
UNSAFE
Fludara may cause side effects which could affect your ability to drive.Some people get tired, feel weak, have disturbed vision, become confused, or agitated or have seizures while they are treated with Fludara and this may affect your ability to drive.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Fludara. Please consult your doctor.
Liver
CAUTION
Fludara should be used with caution in patients with liver disease. Dose adjustment of Fludara may be needed. Please consult your doctor.
Quick Tips
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
References
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 948.
- Fludarabine phosphate. Bedford, Ohio: Ben Venue Laboratories.
- Central Drugs Standard Control Organisation (CDSCO).
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 555-56.
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1702-703.