Grandem Injection


Product Info

Prescription required Yes
Marketer Aristo Pharmaceuticals Pvt Ltd
Active Ingredient Granisetron (1mg)
Storage Store below 30°C
Chemical ClassIndazole Derivative
Habit FormingNo
Therapeutic ClassGASTRO INTESTINAL
Action ClassSerotonin antagonists (5-HT3 antagonists)
User Rating4.8
User Reviews800

FAQ

Question
Is Grandem better than Ondansetron?
Grandem and Ondansetron belong to the same class of medicines, that is serotonin 5-HT3 receptor antagonists. Both these medicines help prevent nausea and vomiting effectively. However, some studies suggest that Grandem is more effective than Ondansetron. According to some reports, Grandem is comparatively well tolerated, quicker in action and alleviates nausea and vomiting relatively faster.
Answer

Question
What are the side effects of Grandem?
The most common side effects of Grandem are sleepiness, weakness, headache, constipation and diarrhea. However, these are not usually bothersome and resolve in some time on their own. Consult your doctor, if the symptoms worry you or persist for a longer duration. Your doctor will suggest ways to cope up with these side effects and to prevent them in future.
Answer

Question
Does Grandem cause constipation?
Yes, Grandem may cause constipation as one of the common side effects. However, this is usually not bothersome. Taking a fiber-rich diet can enhance your digestion and avoid constipation. You may also consider taking laxatives for relief and drink plenty of water too. Avoid drinking alcohol as it may worsen your constipation. If you still face issues, please consult your doctor to know about ways to treat it.
Answer

Question
Is Grandem safe to be used in pregnant women?
Grandem did not show any adverse effects in research studies done on animals. However, since the safety and efficiency of Grandem in pregnant women is unknown. It is not recommended to be used in women who are pregnant women or if you are planning to conceive unless prescribed by your doctor.
Answer

Question
What is Grandem used for?
Grandem is an antiemetic medicine used to treat and prevent nausea or vomiting caused after any surgical procedure or due to certain medicines, stomach upset, or cancer treatment. It also prevents nausea due to motion sickness to some extent.
Answer
Question
What if you forget to take Grandem?
If you miss a dose of Grandem, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
Answer

Grandem Injection Reviews

Grandem is an anti-emetic medicine commonly used to control nausea and vomiting caused due to any surgery, cancer drug therapy, or radiotherapy.

Grandem will not relieve other side effects associated with cancer treatments. It is administered under the supervision of a healthcare professional and should be taken as advised by the doctor. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of injections. 

The most common side effects of taking this medicine include injection site pain or reaction, headache, constipation, diarrhea, and weakness. These symptoms should disappear when you stop taking the medicine but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask advice from your healthcare team.

How Grandem Injection Works

Grandem is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

How to Use Grandem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Grandem Injection

  • In Nausea and vomiting due to chemotherapy: Grandem blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting associated with cancer treatment such as chemotherapy or radiation therapy. This medicine helps you recover more comfortably from these treatments. Grandem is given as an injection by a doctor, in the dose that is best for you, depending on the condition you are being treated for. Do not self-administer this medicine to avoid any undesirable side effects.

Uses of Grandem Injection

  • Nausea and vomiting due to chemotherapy

Grandem Injection Side Effects

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Safety Tips

Pregnancy  SAFE IF PRESCRIBED
Grandem is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding  SAFE IF PRESCRIBED
Grandem is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving  SAFE
Grandem does not usually affect your ability to drive.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Grandem. Please consult your doctor.
Liver  SAFE IF PRESCRIBED
Grandem is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Grandem may not be needed in these patients. Please consult your doctor.
Kidney  SAFE IF PRESCRIBED
Grandem is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Grandem may not be needed in these patients. Please consult your doctor.

Quick Tips

  • Grandem is given as an injection under the supervision of a doctor.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
  • If you vomit within one hour of taking a dose, take another dose.
  • You have been prescribed Grandem for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.

References

  1. Granisetron. Place of publication: Hameln Pharma Plus GmBh; 2008 [revised 8 Oct 2018]. [Accesses on 28 Mar. 2019] (online) Available from:
  2. PubChem. Granisetron.
  3. Drugs.com. Granisetron Pregnancy and Breastfeeding Warnings.

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