Irox 20mg Injection
Product Info
| Prescription required | Yes |
| Marketer | Ultramark Healthcare Pvt Ltd |
| Active Ingredient | Piroxicam (20mg) |
| Storage | Store below 30°C |
| Chemical Class | Enolic acid Derivatives |
| Habit Forming | No |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids) |
| User Rating | 4.5 |
| User Reviews | 784 |
FAQ
Can Irox 20mg be used with lithium?
No. Irox 20mg should not be used with lithium. Irox 20mg leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Can Irox 20mg be used along with Losartan?
No. Irox 20mg should not be combined with Losartan. It is important to note that Irox 20mg decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Irox 20mg.
Can Irox 20mg be used with Lisinopril?
No. Irox 20mg should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Irox 20mg.
Can Irox 20mg be used to treat menstrual cramp?
Irox 20mg is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Can I use Irox 20mg if I have a deranged renal function?
No. Irox 20mg should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Irox 20mg?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Is Irox 20mg a muscle relaxant?
No. Irox 20mg is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
What increases the chances of getting a gastric ulcer when I am already taking Irox 20mg?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Is Irox 20mg a narcotic?
No. Irox 20mg is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
What are the serious side effects of Irox 20mg?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Is Irox 20mg effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Irox 20mg as the cause of back pain can be different for different person.
Can you donate blood when on the medication with Irox 20mg?
Yes. You can donate blood when on Irox 20mg. Do inform your doctor before donating blood.
Is Irox 20mg a blood thinner?
No. Irox 20mg is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Can Irox 20mg be used along with dexamethasone?
No. Irox 20mg should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Can Irox 20mg be used along with paracetamol?
Yes. Paracetamol can be used with Irox 20mg as no serious side effects are known. Inform your doctor before starting any of the medication.
Can I use Irox 20mg if I am a diabetic?
Irox 20mg in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Irox 20mg so taking piroxicam can lead to increased risk of renal failure by many folds.
Is Irox 20mg affective in gout management?
Yes. Irox 20mg can be given for the treatment of acute gout. Research studies have shown Irox 20mg to be highly effective in the treatment of acute gout.
Can Irox 20mg be used in the treatment of allergy?
No. Irox 20mg is not a drug to treat allergy. It is a pain killer.
Why is beta cyclodextrin added to Irox 20mg?
Yes. Irox 20mg can be combined with beta-cyclodextrin. Research has shown that combining Irox 20mg with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Can I use Irox 20mg for a migraine?
Irox 20mg is not approved for the treatment of migraine. Research studies have shown that Irox 20mg is effective in significantly decreasing the pain associated with migraine without aura.
Can Irox 20mg be used with diuretics?
No. Irox 20mg should not be used with diuretics. Irox 20mg reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Can Irox 20mg be used with Tizanidine?
Yes, Irox 20mg can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Is Irox 20mg a sulfa drug?
Irox 20mg is a sulphur containing compound. Irox 20mg can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Can Irox 20mg lead to skin reactions?
Yes. Irox 20mg is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
What is the difference between Irox 20mg and ketoprofen?
Both Irox 20mg and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Irox 20mg. Ketoprofen gel also showed excellent tolerability.
What are the contraindications for Irox 20mg?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Are there any alternatives of Irox 20mg?
Yes. There are alternatives to Irox 20mg. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Can Irox 20mg be used in hypertension?
No. Irox 20mg is not a medication to control hypertension. It is important to note that Irox 20mg decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Irox 20mg.
What is the difference between Irox 20mg and meloxicam?
Both Irox 20mg and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Irox 20mg.
Can I use Irox 20mg if I have peptic ulcer disease?
No. Irox 20mg is contraindicated in cases of active peptic ulcer disease. Irox 20mg is known to cause gastric ulceration and bleeding.
Can you get high by using Irox 20mg?
No. Irox 20mg is not known to cause high. It is a non-narcotic painkiller.
Can Irox 20mg be used with methocarbamol?
Yes. Methocarbamol can be used with Irox 20mg as no serious side effects are known. Inform your doctor before starting any of the medication.
What is the difference between Irox 20mg and diclofenac?
Both Irox 20mg and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Irox 20mg.
Can Irox 20mg be used with warfarin?
No. Irox 20mg should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
How long does Irox 20mg work?
Irox 20mg is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Can Irox 20mg lead to difficulty in conception?
Yes. Irox 20mg can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Can I use Irox 20mg if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
What is the difference between Irox 20mg and tramadol?
Irox 20mg is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Is Irox 20mg a NSAID?
Yes. Irox 20mg is a non-steroidal anti-inflammatory drug (NSAID).
What is the difference between Irox 20mg and naproxen?
Both Irox 20mg and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Irox 20mg.
Are Irox 20mg and aspirin same?
No. Irox 20mg and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Can Irox 20mg be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Irox 20mg or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Irox 20mg.
Can Irox 20mg be used with calcium channel blocker?
Yes. Irox 20mg can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Can I use Irox 20mg if I am pregnant?
No. Irox 20mg should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
What is the difference between Irox 20mg and nimesulide?
Both Irox 20mg and nimesulide are pain killers. However, Irox 20mg is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
What if you forget to take Irox Injection?
If you miss a dose of Irox 20mg, consult your doctor.
Irox 20mg Injection Reviews
Irox 20mg is a pain-relieving medicine. It is used in the treatment of moderate to severe pain. It helps to relieve pain and swelling of various conditions related to joints and muscles. It is usually given in cases where oral administration is unsuitable.
Irox 20mg is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), vomiting, stomach pain, indigestion, diarrhea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
How Irox 20mg Injection Works
Irox 20mg is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
How to Use Irox 20mg Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Irox 20mg Injection
- In Pain relief: Irox 20mg is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Uses of Irox 20mg Injection
- Pain relief
Irox 20mg Injection Side Effects
Safety Tips
Kidney
CAUTION
Irox 20mg should be used with caution in patients with severe kidney disease. Dose adjustment of Irox 20mg may be needed. Please consult your doctor.
Driving
UNSAFE
Irox 20mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Alcohol
CAUTION
Caution is advised when consuming alcohol with Irox 20mg. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Irox 20mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Liver
CAUTION
Irox 20mg should be used with caution in patients with liver disease. Dose adjustment of Irox 20mg may be needed. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Irox 20mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Quick Tips
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Irox 20mg helps relieve pain and swelling of various joints and muscles.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
References
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.
- ScienceDirect. Piroxicam.
- Pubchem. Piroxicam.
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
- Piroxicam [Drug Label]. Metro Manila, Philippines: Pfizer, Inc.; 2022.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
- Central Drugs Standard Control Organisation (CDSCO).