Kyfil 60mg Injection


Product Info

Prescription required Yes
Marketer MSN Laboratories
Active Ingredient Carfilzomib (60mg)
Storage Store in a refrigerator (2 - 8°C). Do not freeze.
Chemical ClassEpoxomicin Derivate
Habit FormingNo
Therapeutic ClassANTI NEOPLASTICS
Action ClassProteasome inhibitor
User Rating4.5
User Reviews718

FAQ

Question
Can Kyfil 60mg be used during breastfeeding?
This medicine may pass into breastmilk and harm the baby. Therefore it is advisable not to breastfeed during the treatment and for 2 weeks after the final dose.
Answer

Question
When should I seek a doctor’s advice?
You should contact your doctor immediately if you develop shortness of breath, prolonged, unusual, or excessive bleeding, yellowing of the skin and/or eyes (jaundice), severe headache, confusion, seizures, or loss of sight.
Answer

Question
Does Kyfil 60mg reduce immunity?
After the start of the treatment with this medicine, your platelet count might become low. As a result, you may be at risk of infection. It is therefore advisable to avoid crowds or people with colds and infections. Wash your hands often and always after using the bathroom.
Answer

Question
I am experiencing nausea and extreme tiredness. Is this due to Kyfil 60mg?
Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.
Answer

Question
What are some of the precautions to be taken while on treatment with Kyfil 60mg?
You might get dehydrated while on treatment with Kyfil 60mg, so it is advisable to increase your fluid intake. This medicine might make you feel dizzy so it is advisable not to drive or operate any machinery. Avoid sun exposure and wear SPF 15 (or higher) sunblock and protective clothing in order to prevent rashes.
Answer

Question
Can Kyfil 60mg be used during pregnancy?
Kyfil 60mg can cause harm to the unborn baby when given to a pregnant woman. Women should use effective contraception during treatment with this medicine and for 6 months following the final dose. Men should use effective contraception during treatment and for 3 months following the final dose.
Answer

Question
Is Kyfil 60mg right for me?
Kyfil 60mg in combination with other medications is for patients with relapsed multiple myeloma (multiple myeloma that has returned) and for refractory multiple myeloma (multiple myeloma that no longer responds to treatment). talk to your doctor in case of any doubts.
Answer

Question
How is Kyfil 60mg administered?
Kyfil 60mg is given as an intravenous (IV) infusion. This is a way to put fluids, including medicine, into your bloodstream through a vein.
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Question
How often will I be given Kyfil 60mg?
You may receive this injection in treatment cycles. Each cycle lasts 4 weeks. The cycle includes days when you are given treatment and days when you do not have treatment (rest periods). You will usually have Kyfil 60mg 2 days a week for 3 weeks. In week 4 you do not have treatment. Your doctor will decide your treatment plan depending on what will work best for you.
Answer

Kyfil 60mg Injection Reviews

Kyfil 60mg is used in the treatment of multiple myeloma. It shows its working by stopping or slowing down the growth of cancer cells.

Kyfil 60mg is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, and fever are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you notice fever, chills, joint or muscle pain, flushing or swelling of the face,  and chest pain. You are advised to drink plenty of fluids while taking this medicine.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

How Kyfil 60mg Injection Works

Kyfil 60mg is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number of proteins in the cancer cells leading to their death.

How to Use Kyfil 60mg Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Kyfil 60mg Injection

  • In Multiple myeloma: If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Kyfil 60mg may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.

Uses of Kyfil 60mg Injection

  • Multiple myeloma

Kyfil 60mg Injection Side Effects

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Safety Tips

Driving  UNSAFE
Kyfil 60mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Breast feeding  UNSAFE
Kyfil 60mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Kyfil 60mg. Please consult your doctor.
Liver  CAUTION
Kyfil 60mg should be used with caution in patients with liver disease. Dose adjustment of Kyfil 60mg may be needed. Please consult your doctor.
Kidney  CAUTION
Kyfil 60mg should be used with caution in patients with kidney disease. Dose adjustment of Kyfil 60mg may be needed. Please consult your doctor.
Pregnancy  CONSULT YOUR DOCTOR
Kyfil 60mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Quick Tips

  • Do not skip any dose and complete the course as suggested by your doctor.
  • You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
  • Let your doctor know if you notice chest pains, shortness of breath, difficulty breathing, dizziness and swelling of feet. 
  • Kyfil 60mg is given as an infusion into the vein ( IV infusion) under the supervision of a doctor only.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 209.
  2. Carfilzomib. Netherlands: Amgen Europe B.V.; 2015 [revised Sep. 2018].
  3. Carfilzomib. South San Francisco, California: Onyx Pharmaceuticals; 2012.
  4. Central Drugs Standard Control Organisation (CDSCO).

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