Leucopar 15mg Injection


Product Info

Prescription required Yes
Marketer Parenteral Drugs India Ltd
Active Ingredient Calcium Leucovorin (15mg)
Salt Synonyms Calcium folinate
Storage Store in a refrigerator (2 - 8°C). Do not freeze.
Chemical ClassGlutamic acid Derivatives
Habit FormingNo
Therapeutic ClassBLOOD RELATED
Action ClassCytoprotective agents- methotrexate
User Rating4.9
User Reviews468

FAQ

Question
What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Leucopar 15mg?
Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.
Answer

Question
What are some of the laboratory tests conducted before or during the treatment with Leucopar 15mg?
Your doctor will prescribe blood tests to check your levels of serum methotrexate concentration (in case of methotrexate chemotherapy or overdose) to determine the optimal dose and duration of treatment with Leucopar 15mg. You will also be prescribed a complete blood count to monitor the number of red blood cells (in case of megaloblastic anemia). Along with this, your calcium levels will also be monitored in order to prevent hypercalcemia (excess calcium) since Leucopar 15mg contains calcium.
Answer

Question
What is Leucopar 15mg used for?
Leucopar 15mg is used to prevent harmful effects of methotrexate (cancer chemotherapy medication) when methotrexate is used to treat certain types of cancer. Leucopar 15mg is also used to treat people who have accidentally received an overdose of methotrexate or similar medications. It is also used for the treatment of megaloblastic anemia due to folic acid deficiency and when oral therapy is not feasible.
Answer

Question
How long does it take for Leucopar 15mg to work?
Leucopar 15mg starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.
Answer

Question
What is megaloblastic anemia?
Anemia is a blood disorder in which the number of red blood cells (RBCs) that carry oxygen is lower than usual. As a result, your tissues and organs don’t get enough oxygen. Megaloblastic anemia is a form of anemia characterized by very large red blood cells and a decrease in the number of those cells. Usually, megaloblastic anemia is due to vitamin B12 or folic acid deficiency. How long does it take for Leucopar 15mg to work?
Answer
Question
What if you forget to take Leucopar Injection?
If you miss a dose of Leucopar 15mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Leucopar 15mg Injection Reviews

Leucopar 15mg is used to prevent the harmful effects of methotrexate (anticancer medicine). It is also used to treat overdose of methotrexate.

Leucopar 15mg is given as a slow injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects.

Injection site reactions (pain, swelling, redness) are common side effects of this medicine. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells and serum methotrexate concentration in blood.

Before taking it, tell your doctor if have seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using, especially phenytoin for your seizures. To make sure it is safe for you, let your doctor know if you are pregnant or breastfeeding before taking this medicine.

How Leucopar 15mg Injection Works

Leucopar 15mg is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.

How to Use Leucopar 15mg Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Leucopar 15mg Injection

  • In Prevention of Harmful effects of methotrexate: Leucopar 15mg helps protect the body cells against the harmful effects of methotrexate, an anti-cancer medicine. It is a form of vitamin B that is given after 24 hours of methotrexate administration. This makes sure that methotrexate has achieved its anti-cancer effects and also, Leucopar 15mg will prevent the other side effects such as anemia.

Uses of Leucopar 15mg Injection

  • Prevention of Harmful effects of methotrexate

Leucopar 15mg Injection Side Effects

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Safety Tips

Pregnancy  CONSULT YOUR DOCTOR
Leucopar 15mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Liver  CONSULT YOUR DOCTOR
There is limited information available on the use of Leucopar 15mg in patients with liver disease. Please consult your doctor.
Driving  SAFE
Leucopar 15mg does not usually affect your ability to drive.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Leucopar 15mg. Please consult your doctor.
Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Leucopar 15mg during breastfeeding is not available. Please consult your doctor.
Kidney  CONSULT YOUR DOCTOR
There is limited information available on the use of Leucopar 15mg in patients with kidney disease. Please consult your doctor.

Quick Tips

  • You have been prescribed Leucopar 15mg to reduce the side effects of the medicine methotrexate.
  • Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Leucopar 15mg may counteract the antiepileptic effects.
  • Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate.

References

  1. Calcium folinate. Hurley, Maidenhead: Hospira UK Ltd.; 2003 [revised Jan. 2018].
  2. Levoleucovorin. Parsippany, New Jersey: Actavis Pharma; 1952 [revised Sep. 2016].

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