Liofen 500 Injection
Product Info
| Prescription required | Yes |
| Marketer | Sun Pharmaceutical Industries Ltd |
| Active Ingredient | Baclofen (500mcg/ml) |
| Storage | Store below 30°C |
| Chemical Class | Gamma Amino Acids Derivative |
| Habit Forming | No |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Skeletal muscle relaxant- Centrally acting |
| User Rating | 4.3 |
| User Reviews | 411 |
FAQ
What’s the most important thing that I should know about Liofen 500?
Suddenly discontinuing intrathecal (given in spinal fluid) Liofen 500 injection may cause serious side effects such as high fever, severe muscle spasm, and rigidity. These side effects can progress to dangerous consequences and can even lead to death. Therefore, the medicine should be gradually reduced.
Can I take Liofen 500 if I have a liver problem?
If you have a liver problem then you need to be cautious while taking Liofen 500. This is because the medicine may increase the production of liver enzymes. Hence, regular laboratory examination of liver enzymes is required while taking this medicine as advised by your doctor.
Can Liofen 500 make you sleepy?
Yes, Liofen 500 can cause sleepiness. It can make a person dizzy due to its sedative effect. It can also affect vision and therefore you should avoid driving and using heavy machinery until and unless you know how Liofen 500 affects you.
How long does Liofen 500 take to work?
Liofen 500 starts working after 0.5-1 hours when the injection is given as a bolus (a large amount of medication is infused at a time). The effect of the medicine can be observed after 4 hours of administration which will last for 4-8 hours. However, if it is given as a continuous infusion then it takes about 6-8 hours to show its effect which reaches its peak within 24 to 48 hours.
Does Liofen 500 help anxiety?
Though Liofen 500 is not approved to treat anxiety disorders, it has been observed in some studies that it is effective in treating stress which occurs after a trauma.
Does Liofen 500 have any effect on kidneys?
Liofen 500 may cause side effects in patients with normal kidney function which include excessive day time urination (pollakiuria), burning sensation while urinating (dysuria), and loss of bladder control (urinary incontinence). Generally, a lower dose of this medicine is prescribed if a person has abnormally functioning kidneys or if a person is on dialysis.
Is Liofen 500 a narcotic?
No, Liofen 500 is not a narcotic. It is a muscle relaxant. It does not have abuse potential. Liofen 500 may cause side effects which include drowsiness, euphoria, and dysphoria. Hence, it should not be used with medicines that cause similar side effects like pain-relieving opiates.
What if you forget to take Liofen Injection?
If you miss a dose of Liofen 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Liofen 500 Injection Reviews
Liofen 500 is a muscle relaxer. It is used to treat muscle symptoms such as rigidity, tension, and stiffness that may occur due to various conditions such as cerebral palsy, multiple sclerosis, motor neuron disease, or injury to the head, brain or spine.
Liofen 500 is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), fatigue, drowsiness, weakness, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have ever had seizures, stomach ulcers, diabetes, problems with your heart, liver, or kidneys, etc. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Liofen 500 is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), fatigue, drowsiness, weakness, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have ever had seizures, stomach ulcers, diabetes, problems with your heart, liver, or kidneys, etc. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
How Liofen 500 Injection Works
Liofen 500 is a muscle relaxant. It works on the brain and spinal cord to relieve muscle stiffness or spasm maintaining the strength of the muscles. This relieves pain and improves movement of muscles.
How to Use Liofen 500 Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Liofen 500 Injection
- In Muscle relaxation: Liofen 500 is a muscle relaxant that is used to relieve rigidity, inflammation, and swelling in conditions that affect skeletal muscles. It works by blocking chemical messengers in the brain that are responsible for such symptoms. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Uses of Liofen 500 Injection
- Muscle relaxation
Liofen 500 Injection Side Effects
Safety Tips
Pregnancy
CONSULT YOUR DOCTOR
Liofen 500 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Kidney
CAUTION
Liofen 500 should be used with caution in patients with kidney disease. Dose adjustment of Liofen 500 may be needed. Please consult your doctor.
Alcohol
UNSAFE
Liofen 500 may cause excessive drowsiness with alcohol.
Breast feeding
SAFE IF PRESCRIBED
Liofen 500 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Liofen 500 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Liver
CAUTION
Liofen 500 should be used with caution in patients with liver disease. Dose adjustment of Liofen 500 may be needed. Please consult your doctor.
Quick Tips
- Liofen 500 provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
- Liofen 500 may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
- Avoid consuming alcohol when taking Liofen 500 as it may cause excessive drowsiness.
References
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Baclofen Pregnancy and Breastfeeding Warnings.
- Baclofen [Prescribing Information]. Plainsboro, NJ: Advagen Pharma Ltd.; 2023.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 121-23.
- Drugs.com. Baclofen Pregnancy and Breastfeeding Warnings.
- White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 463.