Nestig 0.5mg Injection
Product Info
| Prescription required | Yes |
| Marketer | SPM Drugs Pvt Ltd |
| Active Ingredient | Neostigmine (0.5mg) |
| Storage | Store below 30°C |
| Chemical Class | Phenoxy Compounds |
| Habit Forming | No |
| Therapeutic Class | NEURO CNS |
| Action Class | Cholinesterase inhibitors- carbamates |
| User Rating | 4.6 |
| User Reviews | 561 |
FAQ
Is Nestig 0.5mg safe to use?
Yes, Nestig 0.5mg is safe if used in the dose and duration prescribed by the doctor.
Who should not take Nestig 0.5mg?
Nestig 0.5mg should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Nestig 0.5mg is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).
What should I do if I accidentally take more than the dose required?
You should seek immediate medical help in case of overdose of Nestig 0.5mg.Excess of Nestig 0.5mg may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.
Does Nestig 0.5mg have any abuse potential?
No, there is no evidence of Nestig 0.5mg having any abuse potential.
Does it cause weight gain?
No, Nestig 0.5mg does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.
Can I take Nestig 0.5mg for constipation?
No, Nestig 0.5mg should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.
Does Nestig 0.5mg treat myasthenia gravis? How long do I need to take it?
Nestig 0.5mg relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Nestig 0.5mg will depend on your condition. Do not stop taking Nestig 0.5mg until and unless advised by your doctor, even if you start feeling better.
I felt better when I started taking Nestig 0.5mg but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?
If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Nestig 0.5mg. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.
How long does Nestig 0.5mg take to start working?
Nestig 0.5mg takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.
Is Nestig 0.5mg a steroid?
No, Nestig 0.5mg is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Nestig 0.5mg work by preventing the breakdown of a chemical called acetylcholine.
What if you forget to take Nestig Injection?
If you miss a dose of Nestig 0.5mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Nestig 0.5mg Injection Reviews
Nestig 0.5mg is a prescription medicine used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), postoperative urinary retention, and for reversal of effect of skeletal muscle relaxants after surgery.
Nestig 0.5mg works by reducing and improving muscle weakness. It is given as an injection under the supervision of a healthcare professional. Do not skip any doses and finish the full course of treatment and never stop this suddenly without talking to your doctor. However, before taking this medicine it is better to inform your doctor if you are suffering from any kidney disease, Parkinson's disease, asthma, or stomach disorders.
The most common side effects of this medicine are slow heart rate, nausea, and
vomiting. If you any other symptoms which you think are caused by the medicine, you should let your doctor know. They may be able to suggest ways to reduce or prevent the side effects. Pregnant and breastfeeding women should consult the doctor before taking this medicine.
Nestig 0.5mg works by reducing and improving muscle weakness. It is given as an injection under the supervision of a healthcare professional. Do not skip any doses and finish the full course of treatment and never stop this suddenly without talking to your doctor. However, before taking this medicine it is better to inform your doctor if you are suffering from any kidney disease, Parkinson's disease, asthma, or stomach disorders.
The most common side effects of this medicine are slow heart rate, nausea, and
vomiting. If you any other symptoms which you think are caused by the medicine, you should let your doctor know. They may be able to suggest ways to reduce or prevent the side effects. Pregnant and breastfeeding women should consult the doctor before taking this medicine.
How Nestig 0.5mg Injection Works
Nestig 0.5mg is a reversible cholinesterase inhibitor. It increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.
How to Use Nestig 0.5mg Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Nestig 0.5mg Injection
- In Treatment of Paralytic ileus: Paralytic ileus is the obstruction of the intestines due to improper functioning of the nerves and muscles in the intestine that impairs digestive movement. Nestig 0.5mg induces contractions in the intestinal muscles and improves their function. As a result, there is better movement of food and this treats the obstruction. Take it as advised by the doctor and follow your doctor’s instructions carefully.
- In Reversal of effect of skeletal muscle relaxant after surgery: Skeletal muscle relaxants are given to induce anesthesia and to carry out surgical or certain diagnostic procedures. This blocks the conduction of signals between nerves and muscles. After the surgery, Nestig 0.5mg is given to reverse this effect and cause muscle contraction again to restore normal function.
- In Treatment of Myasthenia gravis: Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Nestig 0.5mg makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.
- In Treatment of Post-operative urinary retention: After an operation, there may be problems in emptying the bladder. This may be due to disturbed coordination of nerves and muscles of the bladder. Nestig 0.5mg helps to improve this problem and treats postoperative urinary retention effectively.
Uses of Nestig 0.5mg Injection
- Treatment of Post-operative urinary retention
- Treatment of Myasthenia gravis
- Reversal of effect of skeletal muscle relaxant after surgery
- Treatment of Paralytic ileus
Nestig 0.5mg Injection Side Effects
Safety Tips
Alcohol
UNSAFE
Nestig 0.5mg may cause excessive drowsiness with alcohol.
Kidney
CAUTION
Nestig 0.5mg should be used with caution in patients with kidney disease. Dose adjustment of Nestig 0.5mg may be needed. Please consult your doctor.Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.
Pregnancy
CONSULT YOUR DOCTOR
Nestig 0.5mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Nestig 0.5mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Breast feeding
SAFE IF PRESCRIBED
Nestig 0.5mg is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Liver
SAFE IF PRESCRIBED
Nestig 0.5mg is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nestig 0.5mg may not be needed in these patients. Please consult your doctor.
Quick Tips
- Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.
- Do not drink alcohol while taking this medicine as it may worsen the side effects.
- It is given into veins, muscles or under the skin by a healthcare professional.
References
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Neostigmine. [Updated 2018 Oct 31].
- Drugs.com. Neostigmine Pregnancy and Breastfeeding Warnings.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 969.
- Neostigmine. Gloucester Business Park, Gloucester: Hameln Pharmaceuticals Ltd.; 2001 [revised 12 Jan. 2018].
- Neostigmine Methylsulfate Injection [FDA Label]. Chesterfield, MO: Éclat Pharmaceuticals; 2013.