Nitrosol 5mg Injection
Product Info
| Prescription required | Yes |
| Marketer | Shree Ganesh Pharmaceuticals |
| Active Ingredient | Nitroglycerin (5mg) |
| Salt Synonyms | Glyceryl Trinitrate |
| Storage | Store below 30°C |
| Chemical Class | Nitrates {Short acting} |
| Habit Forming | No |
| Therapeutic Class | CARDIAC |
| Action Class | NO Donors |
| User Rating | 4.6 |
| User Reviews | 680 |
FAQ
What does too much Nitrosol 5mg do?
Excess Nitrosol 5mg may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.
Does the effect of Nitrosol 5mg wear off after sometime?
Yes, excessive use of Nitrosol 5mg may cause tolerance which means that Nitrosol 5mg may lose its effectiveness on you. Therefore, doctors usually prescribe the smallest dose required for effective relief of acute angina attacks. Also, it is usually prescribed in morning and afternoon doses to give nitrate-free interval. Take it strictly as per the dosing interval prescribed by your doctor to prevent tolerance and maintain the effectiveness of Nitrosol 5mg.
Does Nitrosol 5mg stop heart attacks?
Nitrosol 5mg is prescribed to prevent attacks of heart-related chest pain (angina) in patients with coronary artery disease. In this disease, the blood vessels (coronary arteries) which supply blood to the heart become narrow because of which the heart has to work harder to get enough oxygen. Nitrosol 5mg prevents angina by relaxing the blood vessels so that the heart does not have to work very hard. Also, relaxation of coronary arteries increases the oxygen supply to the heart.
What if you forget to take Nitrosol Injection?
If you miss a dose of Nitrosol 5mg, consult your doctor.
Nitrosol 5mg Injection Reviews
Nitrosol 5mg is used to treat and prevent heart-related chest pain (angina) and hypertension (high blood pressure) during surgery. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect.
Nitrosol 5mg is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind.
The most common side effect of Nitrosol 5mg is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.
Do not use Nitrosol 5mg if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.
Nitrosol 5mg is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind.
The most common side effect of Nitrosol 5mg is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.
Do not use Nitrosol 5mg if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.
How Nitrosol 5mg Injection Works
Nitrosol 5mg is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure.
How to Use Nitrosol 5mg Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Nitrosol 5mg Injection
- In Treatment of Angina (heart-related chest pain): Nitrosol 5mg helps in prevention as well as treatment of angina. Angina is a chest pain that is usually caused by narrowing of the blood vessels which supply your heart. This means your heart does not get enough oxygen. Nitrosol 5mg works quickly to relax the muscles and blood vessels in your heart so more blood (and oxygen) gets to your heart. This reduces the pain and discomfort that angina causes.You should take this medicine at the first sign of chest pain. If the first tablet does not work, you can take a second tablet after 5 minutes. However, if your chest pain does not go away after 15 minutes, you should get urgent medical attention. This could be a sign of a heart attack. Nitrosol 5mg also helps prevent chest pain if taken before exercising or doing other strenuous activities.
- In Treatment of Hypertension (high blood pressure): Nitrosol 5mg is used to treat hypertension in hypertensive emergencies. It rapidly dilates (widens) the blood vessels. This rapid vasodilation helps reduce blood pressure levels, relieving the strain on the heart and improving blood flow to vital organs. It is typically used in critical situations where immediate blood pressure reduction is necessary, such as severe high blood pressure that can lead to organ damage or other life-threatening complications.
Uses of Nitrosol 5mg Injection
- Treatment of Hypertension (high blood pressure)
- Treatment of Angina (heart-related chest pain)
Nitrosol 5mg Injection Side Effects
Safety Tips
Driving
UNSAFE
Nitrosol 5mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Breast feeding
SAFE IF PRESCRIBED
Nitrosol 5mg is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Kidney
SAFE IF PRESCRIBED
Nitrosol 5mg is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrosol 5mg may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Nitrosol 5mg in patients with liver disease. Please consult your doctor.
Alcohol
UNSAFE
Consuming alcohol while taking Nitrosol 5mg may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
SAFE IF PRESCRIBED
Nitrosol 5mg is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Quick Tips
- Do not consume alcohol while taking Nitrosol 5mg as it may cause increased dizziness.
- It is given via a drip into a vein under the supervision of a doctor.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrosol 5mg as it may cause low blood pressure.
- Nitrosol 5mg may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
References
- Nitroglycerin Injection [Product Information].
- Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 191, 195-97.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 986-88.
- Nitroglycerin Injection [FDA Label]. Shirley, NY: American Regent Laboratories Inc.; 2022.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroglycerin. [Updated 2018 Oct 31].
- Central Drugs Standard Control Organisation (CDSCO).
- Nitroglycerin [FDA Label]. Deerfield, IL: Baxter Healthcare Corporation; 2014.
- Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.