Paclistar 260mg Injection
Product Info
| Prescription required | Yes |
| Marketer | Lupin Ltd |
| Active Ingredient | Paclitaxel (260mg) |
| Storage | Store below 30°C |
| Chemical Class | Taxanes Derivatives |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimicrotubule agents- Taxanes |
| User Rating | 4.6 |
| User Reviews | 767 |
FAQ
Is Paclistar 260mg a vesicant?
Paclistar 260mg is usually a vesicant (irritant)
Does Paclistar 260mg cause hair loss?
Yes, Paclistar 260mg may cause hair loss as a side effect. Please inform your doctor about any side effect while you are on Paclistar 260mg therapy
What is Paclistar 260mg derived from?
Paclistar 260mg is derived from bark of the Pacific yew, Taxus brevifolia.
Is Paclistar 260mg generic/ taxane/ FDA approved/cytotoxic?
Yes, Paclistar 260mg is generic/ taxane/ FDA approved/ cytotoxic
Is Paclistar 260mg light sensitive/ hydrophobic/ cardiotoxic?
Yes, Paclistar 260mg is light sensitive/ hydrophobic/ cardiotoxic
Paclistar 260mg Injection Reviews
Paclistar 260mg is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include nausea, vomiting, and weakness. It may also cause serious side effects such as swelling of hands, lips, hair loss, and weight gain. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include nausea, vomiting, and weakness. It may also cause serious side effects such as swelling of hands, lips, hair loss, and weight gain. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
How Paclistar 260mg Injection Works
Paclistar 260mg is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.
How to Use Paclistar 260mg Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Paclistar 260mg Injection
- In Breast cancer: Paclistar 260mg helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Paclistar 260mg kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
- In Non-small cell lung cancer: Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Paclistar 260mg helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
- In Pancreatic cancer: Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Paclistar 260mg helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.
Uses of Paclistar 260mg Injection
- Breast cancer
- Pancreatic cancer
- Non-small cell lung cancer
Paclistar 260mg Injection Side Effects
- Rash
- Diarrhea
- Decreased blood pressure
- Urinary tract infection
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Nausea
- Weakness
- Upper respiratory tract infection
- Decreased white blood cell count (neutrophils)
- Hair loss
- Bleeding
- Anemia (low number of red blood cells)
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Low blood platelets
- Vomiting
Safety Tips
Alcohol
UNSAFE
It is unsafe to consume alcohol with Paclistar 260mg.
Breast feeding
UNSAFE
Paclistar 260mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Liver
CAUTION
Paclistar 260mg should be used with caution in patients with liver disease. Dose adjustment of Paclistar 260mg may be needed. Please consult your doctor.Use of Paclistar 260mg is not recommended in patients with severe liver disease.
Driving
UNSAFE
Paclistar 260mg may cause side effects which could affect your ability to drive.As there is no reason why you cannot continue driving between courses of Paclistar 260mg but you should remember that this medicine contains some alcohol and it may be unwise to drive
Kidney
SAFE IF PRESCRIBED
Paclistar 260mg is safe to use in patients with kidney disease. No dose adjustment of Paclistar 260mg is recommended.However, talk to your doctor if you have any underlying kidney disease.
Pregnancy
CONSULT YOUR DOCTOR
Paclistar 260mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Quick Tips
- Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn't go away.
- Do not take Paclistar 260mg if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
- Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
- It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.
- Paclistar 260mg is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.
- Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1044-46.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 949.
- Paclitaxel. Hurley, Maidenhead: Hospira UK Ltd.; 2005 [revised Dec. 2016].
- Paclitaxel. Summit, New Jersey: Celgene Corporation; 2005 [revised Oct. 2012].
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paclitaxel. [Updated 2020 Jan 20].
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1707-709.