Pemeta 500 Injection
Product Info
| Prescription required | Yes |
| Marketer | Cipla Ltd |
| Active Ingredient | Pemetrexed (500mg) |
| Storage | Store in a refrigerator (2 - 8°C). Do not freeze. |
| Chemical Class | Glutamic Aacid Derivatives |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| User Rating | 4.7 |
| User Reviews | 415 |
FAQ
Is Pemeta 500 safe?
Pemeta 500 is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Is Pemeta 500 a vesicant?
No. Pemeta 500 is not a vesicant.
Does Pemeta 500 cause hair loss?
Yes. Pemeta 500 is a prescription chemotherapy medication and hair loss is one of the possible side effects.
Pemeta 500 Injection Reviews
Pemeta 500 is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.
Pemeta 500 is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Pemeta 500 is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
How Pemeta 500 Injection Works
Pemeta 500 interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
How to Use Pemeta 500 Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Pemeta 500 Injection
- In Malignant pleural mesothelioma: Malignant pleural mesothelioma is a form of cancer that develops in the lungs and the inner side of the ribs. It is a very aggressive form of lung cancer. Pemeta 500 is used along with some other medicines to treat this cancer. It kills the cancer cells, and prevents the further multiplication of cancer cells. This restricts the spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and consult your doctor if you have any doubts.
- In Non-small cell lung cancer: Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Pemeta 500 helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Uses of Pemeta 500 Injection
- Malignant pleural mesothelioma
- Non-small cell lung cancer
Pemeta 500 Injection Side Effects
Safety Tips
Driving
UNSAFE
Pemeta 500 may cause side effects which could affect your ability to drive.Pemeta 500 may make you feel tired and this may affect your ability to drive.
Liver
SAFE IF PRESCRIBED
Pemeta 500 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pemeta 500 may not be needed in these patients. Please consult your doctor.
Breast feeding
CAUTION
Pemeta 500 should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Kidney
CAUTION
Pemeta 500 should be used with caution in patients with kidney disease. Dose adjustment of Pemeta 500 may be needed. Please consult your doctor.Use of Pemeta 500 is not recommended in patients with moderate to severe kidney disease.
Pregnancy
CONSULT YOUR DOCTOR
Pemeta 500 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Alcohol
SAFE
Consuming alcohol with Pemeta 500 does not cause any harmful side effects.
Quick Tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
References
- Pemetrexed disodium. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 10 Jan. 2019].
- Central Drugs Standard Control Organisation (CDSCO).
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 946.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1077.
- Pemetrexed. Indianapolis, Indiana: Lilly USA; 2004 [revised Sep. 2013].