Pexetrust 500mg Injection


Product Info

Prescription required Yes
Marketer Panacea Biotec Pharma Ltd
Active Ingredient Pemetrexed (500mg)
Storage Store in a refrigerator (2 - 8°C). Do not freeze.
Chemical ClassGlutamic Aacid Derivatives
Habit FormingNo
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolites
User Rating4.8
User Reviews498

FAQ

Question
Is Pexetrust 500mg a vesicant?
No. Pexetrust 500mg is not a vesicant.
Answer

Question
Is Pexetrust 500mg safe?
Pexetrust 500mg is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Answer

Question
Does Pexetrust 500mg cause hair loss?
Yes. Pexetrust 500mg is a prescription chemotherapy medication and hair loss is one of the possible side effects.
Answer

Pexetrust 500mg Injection Reviews

Pexetrust 500mg is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.

Pexetrust 500mg is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

How Pexetrust 500mg Injection Works

Pexetrust 500mg interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

How to Use Pexetrust 500mg Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Benefits of Pexetrust 500mg Injection

  • In Non-small cell lung cancer: Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Pexetrust 500mg helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
  • In Malignant pleural mesothelioma: Malignant pleural mesothelioma is a form of cancer that develops in the lungs and the inner side of the ribs. It is a very aggressive form of lung cancer. Pexetrust 500mg is used along with some other medicines to treat this cancer. It kills the cancer cells, and prevents the further multiplication of cancer cells. This restricts the spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and consult your doctor if you have any doubts.

Uses of Pexetrust 500mg Injection

  • Malignant pleural mesothelioma
  • Non-small cell lung cancer

Pexetrust 500mg Injection Side Effects

Item form

Safety Tips

Breast feeding  CAUTION
Pexetrust 500mg should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Liver  SAFE IF PRESCRIBED
Pexetrust 500mg is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pexetrust 500mg may not be needed in these patients. Please consult your doctor.
Kidney  CAUTION
Pexetrust 500mg should be used with caution in patients with kidney disease. Dose adjustment of Pexetrust 500mg may be needed. Please consult your doctor.Use of Pexetrust 500mg is not recommended in patients with moderate to severe kidney disease.
Pregnancy  CONSULT YOUR DOCTOR
Pexetrust 500mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Alcohol  SAFE
Consuming alcohol with Pexetrust 500mg does not cause any harmful side effects.
Driving  UNSAFE
Pexetrust 500mg may cause side effects which could affect your ability to drive.Pexetrust 500mg may make you feel tired and this may affect your ability to drive.

Quick Tips

  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.

References

  1. Pemetrexed disodium. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 10 Jan. 2019].
  2. Pemetrexed. Indianapolis, Indiana: Lilly USA; 2004 [revised Sep. 2013].
  3. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 946.
  4. Central Drugs Standard Control Organisation (CDSCO).
  5. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1077.

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