Pyrolate Injection
Product Info
Prescription required | Yes |
Marketer | Neon Laboratories Ltd |
Active Ingredient | Glycopyrrolate (0.2mg) |
Storage | Store below 30°C |
Chemical Class | Synthetic Quaternary Ammonium |
Habit Forming | No |
Therapeutic Class | GASTRO INTESTINAL |
Action Class | Anticholinergic - Anaesthesia |
User Rating | 4.6 |
User Reviews | 638 |
FAQ
Does Pyrolate cause tachycardia?
Yes, Pyrolate has its action on the heart which increases the heart rate (tachycardia). This property of the medication is utilized during surgery to prevent the fall of heart rate due to various other supplemental anesthetic medications.
Does Pyrolate increase blood pressure?
Yes, Pyrolate can sometimes lead to an increase in blood pressure. There are evidences where it has led to increased blood pressure. Therefore, when injected into a patient during a surgery, the heart rate and blood pressure are continuously monitored.
I am on antidepressants currently. Can I take Pyrolate?
Some classes of antidepressant medicines can worsen the side effects of Pyrolate and cause uneasiness for the patient. These antidepressant medicines may include tricyclic antidepressants (amitriptyline or imipramine), phenelzine, tranylcypromine, clozapine, etc. Therefore, do inform your doctor about your previous illness and the medicines you are taking before you take this medication. Your doctor may make the necessary adjustments.
Can Pyrolate cause constipation?
Yes, Pyrolate can cause constipation because of its action on the intestine. It decreases the intestinal secretions and also decreases the gut motility which can result in constipation.
Is Pyrolate a narcotic?
No, Pyrolate is not a narcotic.
Pyrolate Injection Reviews
Pyrolate is an anticholinergic medication. It is used before or even during an operation to reduce secretions and it even reverses the unwanted effects of certain medicines used during surgery (muscle relaxants). It also helps to treat peptic ulcers when oral medication is not tolerated.
Pyrolate is given by your doctor or nurse. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.
The most common side effects of this medicine include dry mouth, urinary retention, blurred vision, photophobia, dilation of the pupil, cycloplegia, increased heart rate, increased eye pressure, tachycardia, bradycardia, palpitation, and reduced sweating. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Inform your doctor if you have glaucoma, myasthenia gravis, heart failure, and high blood pressure.
Pyrolate is given by your doctor or nurse. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.
The most common side effects of this medicine include dry mouth, urinary retention, blurred vision, photophobia, dilation of the pupil, cycloplegia, increased heart rate, increased eye pressure, tachycardia, bradycardia, palpitation, and reduced sweating. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Inform your doctor if you have glaucoma, myasthenia gravis, heart failure, and high blood pressure.
How Pyrolate Injection Works
Pyrolate is an anticholinergic medication. It works by blocking the activity of a chemical messenger (acetylcholine) in the brain.
How to Use Pyrolate Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Pyrolate Injection
- In General Anaesthesia: Pyrolate is used before and during surgery to reduce secretions of the mouth, throat, or stomach, such as saliva, stomach acid, or to prevent problems related to heart rhythm during anesthesia, intubation, or surgery. It also helps decrease the unwanted effects that may be caused by certain medicines like, neostigmine, pyridostigmine, etc. It is given by a specialist doctor called an anesthetist in a hospital setup.
- In Peptic ulcer disease: Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Pyrolate reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer.
Uses of Pyrolate Injection
- Peptic ulcer disease
- General Anaesthesia
Pyrolate Injection Side Effects
Safety Tips
Breast feeding
SAFE IF PRESCRIBED
Pyrolate is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.Long-term use of Pyrolate might reduce milk production.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Pyrolate in patients with liver disease. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Pyrolate is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pyrolate. Please consult your doctor.
Kidney
CAUTION
Pyrolate should be used with caution in patients with kidney disease. Dose adjustment of Pyrolate may be needed. Please consult your doctor.
Driving
UNSAFE
Pyrolate may cause side effects which could affect your ability to drive.Pyrolate may affect vision and coordination. This may affect your driving ability.
Quick Tips
- It is given as an injection into a muscle or into a vein.
- It may also be used to reduce side effects of muscle-relaxing drugs and to prevent of slowing of heart beat during surgery.
- Use caution while driving or doing anything that requires concentration as Pyrolate may cause dizziness and blurred vision.
- Pyrolate is used before an operation, to reduce saliva and other secretions and to make the stomach contents less acidic.
References
- Central Drugs Standard Control Organisation. Glycopyrrolate.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Glycopyrrolate. [Updated 2018 Dec 3].
- Glycopyrrolate Injection [Prescribing Information]. Lake Zurich, IL: Fresenius Kabi; 2022.