Thiopta Injection
Product Info
| Prescription required | Yes |
| Marketer | Celon Laboratories Ltd |
| Active Ingredient | Thiotepa (15mg) |
| Storage | Store below 30°C |
| Chemical Class | Thiophosphoric Acids Derivatives |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkylating agent |
| User Rating | 4.3 |
| User Reviews | 321 |
FAQ
What if you forget to take Thiopta?
If you miss a dose of Thiopta, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Thiopta Injection Reviews
Thiopta is used in the treatment of cancers of the brain, breast, lungs, and ovaries. It is used in combination with other cancer medicine during hematopoietic progenitor cell transplantation (HPCT). It may be also used to treat other conditions, as determined by the doctor.
Thiopta is generally given under the supervision of a healthcare professional. Your doctor will decide the dose and duration of the treatment based on the severity of your condition and what you are being treated for. It may take several weeks or months for you to see or feel the benefits but do not stop getting the injection unless your doctor tells you to.
The most common side effects of this medicine include decreased white blood count, anemia, low blood platelets, increased liver enzymes, increased bilirubin in the blood, mucosal inflammation, hemorrhage, diarrhea, blood in urine, and rash. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidneys, liver, and heart function during treatment with this medicine.
Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Thiopta is generally given under the supervision of a healthcare professional. Your doctor will decide the dose and duration of the treatment based on the severity of your condition and what you are being treated for. It may take several weeks or months for you to see or feel the benefits but do not stop getting the injection unless your doctor tells you to.
The most common side effects of this medicine include decreased white blood count, anemia, low blood platelets, increased liver enzymes, increased bilirubin in the blood, mucosal inflammation, hemorrhage, diarrhea, blood in urine, and rash. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidneys, liver, and heart function during treatment with this medicine.
Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
How Thiopta Injection Works
Thiopta is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
How to Use Thiopta Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Thiopta Injection
- In Ovarian cancer: Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Thiopta kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor.
- In Non-small cell lung cancer: Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Thiopta helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Uses of Thiopta Injection
- Non-small cell lung cancer
- Ovarian cancer
- Brain tumor
- Breast cancer
Thiopta Injection Side Effects
Safety Tips
Breast feeding
UNSAFE
Thiopta is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Liver
CAUTION
Thiopta should be used with caution in patients with liver disease. Dose adjustment of Thiopta may be needed. Please consult your doctor.Regular monitoring of liver function tests may be advised while you are taking this medicine.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Thiopta. Please consult your doctor.
Kidney
SAFE IF PRESCRIBED
Thiopta is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Thiopta may not be needed in these patients. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Thiopta is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Driving
UNSAFE
Thiopta may cause side effects which could affect your ability to drive.It is likely that certain adverse events of Thiopta are dizziness, headache, and blurred vision which could affect your ability to drive.
Quick Tips
- Thiopta is given as an intravenous infusion (IV infusion) under the supervisión of a doctor.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- It makes you feel dizzy. Do not drive or operate machinery until you know how it affects you.
- Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1685.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1355-56.
- Drugs.com. Thiotepa Pregnancy and Breastfeeding Warnings.
- Thiotepa. Lugano, Switzerland: ADIENNE SA; 1959 [revised Jan. 2017].