Zotide One Injection
Product Info
| Prescription required | Yes |
| Marketer | Cipla Ltd |
| Active Ingredient | Teriparatide (600mcg) |
| Storage | Store in a refrigerator (2 - 8°C). Do not freeze. |
| Chemical Class | Parathyroid Hormone Analogs |
| Habit Forming | No |
| Therapeutic Class | HORMONES |
| Action Class | Bone formation stimulator -PTH analogue |
| User Rating | 4.1 |
| User Reviews | 653 |
FAQ
How is Zotide One stored at home?
Always keep this medicine stored in a refrigerator at a temperature of about 2°C to 8°C. Be cautious, the temperature should not decrease further as freezing may cause the medicine to get damaged and can lead to loss of activity. Therefore, avoid placing the Zotide One pens close to the ice compartment of the refrigerator. If properly stored this medication can be used up to 28 days after the first injection. If the pen is not empty within 28 days please discard it safely.
Is Zotide One a steroid?
No, Zotide One is not a steroid. However, this medicine may be used to treat osteoporosis caused by long-term use of steroids. Generally, this medicine is used to treat osteoporosis in women of postmenopausal age group and in men who have increased risk of fracture.
Can I take this medication in long term for osteoporosis?
Zotide One should not be taken for longer than 2-year course. It is important to inform the doctor if you have taken this medication in the past, as you should not receive more than one treatment of 24 months course more than once in your lifetime.
Who should not use Zotide One?
The doctor will decide whether the medicine is required for a patient or not. There are few conditions in which the use of Zotide One should be avoided such as in patients with kidney impairment, Paget’s disease, any type of bone cancers or unexplained high levels of serum calcium. It should also be avoided by children, young adult or growing age, pregnant or lactating females. Hence, before starting the medication inform the doctor about any medical condition and the medication you are taking. This will help the doctor to design a proper therapy for you.
What if you forget to take Zotide One?
If you miss a dose of Zotide One, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Zotide One Injection Reviews
Zotide One is a man-made version of parathyroid hormone used to treat men and postmenopausal women who have severe osteoporosis with a high risk of fractures. It works by stimulating new bone formation, which improves bone density and decreases the risk of spinal fractures.
Zotide One should be injected under the skin or given by a healthcare professional. You should use it regularly and at the same time each day to get the maximum benefit from it. Usually, it is recommended to take it for a maximum period of 2 years. However, follow the doctor’s advice and complete the course even if you feel better. It should be stored in the refrigerator at a temperature of 2°C to 8°C.
Some common side effects of this medicine include joint pain, injection site reactions (such as pain, swelling, and redness) and leg cramps. consult with your doctor if any of these bother you or do not go away.
Before taking this medicine, let your doctor know if you have kidney stones or any other kidney problems, as it can cause an increase in the amount of calcium in blood or urine. Pregnant and breastfeeding mothers should also consult with their doctors before taking this medicine. Your doctor may advise a bone scan to monitor the progress of your treatment.
How Zotide One Injection Works
Zotide One is a synthetic form of a natural human hormone called parathyroid hormone (PTH). It works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.
How to Use Zotide One Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Benefits of Zotide One Injection
- In Osteoporosis: Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. Zotide One helps treat osteoporosis in men as well as in women after menopause. It slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is given by a doctor or nurse and should not be self-administered. You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.
Uses of Zotide One Injection
- Osteoporosis
Zotide One Injection Side Effects
Safety Tips
Kidney
CAUTION
Zotide One should be used with caution in patients with kidney disease. Dose adjustment of Zotide One may be needed. Please consult your doctor.Use of Zotide One is not recommended in patients with severe kidney disease.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Zotide One during breastfeeding is not available. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zotide One in patients with liver disease. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Zotide One may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Driving
UNSAFE
Zotide One may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Alcohol
CAUTION
Caution is advised when consuming alcohol with Zotide One. Please consult your doctor.
Quick Tips
- Do not take it for more than 2 years.
- You may have low blood pressure and dizziness during the initial few days.
- Tell your doctor immediately if you experience nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs of high calcium levels in your blood.
- If you feel dizzy (light-headed) after injection, sit or lie down until you feel better.
- Tell your doctor if you are breastfeeding, pregnant or plan to become pregnant.
- Zotide One should be injected every day under the skin (subcutaneous injection) of the thigh or abdomen.
References
- Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
- Teriparatide injection [Prescribing Inforamtion]. Indianapolis, IN: : Lilly USA, LLC; 2021.
- Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1300
- Central Drugs Standard Control Organisation (CDSCO).
- Teriparatide. Indianapolis, Indiana: Lilly France; 2008.