Metacin 250mg Suppository
Product Info
| Prescription required | No |
| Marketer | Themis Pharmaceuticals Prop Chemosyn Ltd |
| Active Ingredient | Paracetamol (250mg) |
| Salt Synonyms | Acetaminophen |
| Storage | Store below 30°C |
| Chemical Class | P-Aminophenol Derivative |
| Habit Forming | No |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Analgesic & Antipyretic-PCM |
| User Rating | 4.9 |
| User Reviews | 320 |
FAQ
Where should I store this medicine?
Keep this medicine beyond the reach of the children. To prevent melting, keep the medicine in the refrigerator but do not freeze.
How should Metacin 250mg be used?
Metacin 250mg is meant to be placed inside the rectum (bottom area). It uses the body's heat and melts inside, resulting in direct absorption into the bloodstream and rendering quick relief. Use Metacin 250mg as directed by your child’s doctor. Before insertion, wash your hands properly. Guide your child to lie down sideways or on the belly. Hold one buttock gently to get access to the rectal area. Unwrap the medicine and hold the rounded end close to the rectum. Use one finger to gently push Metacin 250mg into the rectum. Ask your child to remain still for about 15 minutes as it will prevent the medicine from popping out. Clean your hands again with soap and water to ensure hygiene.
How much Metacin 250mg should I give to my child?
It will depend on the strength of the medicine and the age of your child. Always follow your doctor's instructions regarding how much and how often the medicine should be given to your child. In case you are not sure about how much to give, consult your child’s doctor.
In what conditions should Metacin 250mg be given with caution?
It is advised to use Metacin 250mg with caution if the child has malnutrition, G6PD deficiency, liver disease, or any medicinal allergy. So, do not hesitate to share your child’s complete medical history with the doctor as that will help the doctor decide whether the medicine is safe for your child or not.
My child’s fever is persistent even after taking Metacin 250mg. What should I do?
If the fever doesn't come down, the cause might be an infection (virus or bacteria). It is advised to consult your child’s doctor for specific treatment.
Can I give Metacin 250mg to my child for low-grade fever?
You can give this medicine if your child has a temperature of 38.3°C (101°F) or higher. But, you must always try to speak to your child’s doctor first.
What if I forget to give Metacin 250mg to my child?
Do not panic. Unless your doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember it. Skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
Metacin 250mg Suppository Reviews
Metacin 250mg helps ease pain and bring down high body temperature (fever). It works by blocking certain chemical messengers in the brain that increase the body’s temperature and cause pain. It is usually only given to children who are unable to take oral forms of this medicine.
Metacin 250mg is for rectal use only and should never be taken by mouth. Encourage your child to empty the bowel before inserting the medicine as that will enhance the absorption of the medicine. Also, ask your child to slow down and avoid moving around a lot at least for an hour after placing the medicine. The dose will depend upon your child’s age, body weight, and severity of the infection, so stick to the dose, duration, and way prescribed by your child’s doctor. If your child passes stool within 30 minutes of inserting Metacin 250mg, you will have to insert it again.
Do not give your child Metacin 250mg along with other medicines (many cold and flu medicines and other painkillers) that contain paracetamol, as this may result in overdosing and cause dangerous side effects such as hepatotoxicity (liver damage). Always check the ingredients of any other medicine before giving them to your child in combination with this medicine. Also, do not stop giving the medicine abruptly even if your child starts to feel better. Doing so may bring back the symptoms or worsen the condition.
Generally, this medicine is well-tolerated by the children. However, temporary side effects such as anal irritation, nausea, vomiting, and constipation may occur in some children. Consult your doctor in case these episodes become bothersome for your child.
This medicine is often considered safe and effective but may not be suitable for everybody. Inform your doctor if your child is undergoing treatment for any blood-related disorder, is allergic to any medicinal compound, or has any birth defects, liver impairment, or kidney dysfunction. This will help your child’s doctor evaluate the dose and suitability of this medicine in a better way.
How Metacin 250mg Suppository Works
Metacin 250mg possesses analgesic (pain-reliever) and antipyretic (lowers body temperature) properties. It is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it provides relief by blocking certain chemical messengers and pathways in the brain that send signals about pain and fever.
How to Use Metacin 250mg Suppository
Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
Benefits of Metacin 250mg Suppository
- In Treatment of Fever: Metacin 250mg is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.
- In Pain relief: Metacin 250mg is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage. Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. It is also the first choice of painkiller during pregnancy or breastfeeding.
Uses of Metacin 250mg Suppository
- Treatment of Fever
- Pain relief
Metacin 250mg Suppository Side Effects
Safety Tips
Kidney
CAUTION
Metacin 250mg should be used with caution in patients with severe kidney disease. Dose adjustment of Metacin 250mg may be needed. Please consult your doctor.However, Metacin 250mg contains paracetamol which is considered the safest painkiller for children with kidney disease.
Liver
CAUTION
Metacin 250mg should be used with caution in patients with liver disease. Dose adjustment of Metacin 250mg may be needed. Please consult your doctor.However, the use of Metacin 250mg is not recommended in children with severe liver disease and active liver disease.
Quick Tips
- This medicine is for rectal use only and should not be taken by mouth.
- Never give any other medicine formulation containing paracetamol along with this medicine as that may lead to serious side effects.
- If Metacin 250mg does not seem to be helping your child, contact your doctor for advice. Do not give extra doses.
- Inform the doctor if your child has liver disease as the dose may need to be adjusted.
- Metacin 250mg is for use in children who find it difficult to take paracetamol as tablets or syrup.
References
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- Paracetamol [Package Leaflet]. Norfolk, UK: Amdeepcha Limited; 2022.
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- Royal College of Paediatrics and Child Health. Medicines for Children - information for parents and carers.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
- Section on Clinical Pharmacology and Therapeutics; Committee on Drugs, Sullivan JE, Farrar HC. Fever and antipyretic use in children. Pediatrics. 2011;127(3):580-7.
- Grosser T, Smyth E, FitzGerald G. Pharmacotherapy of Inflammation, Fever, Pain, and Gout. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018.
- Paracetamol [EMC Patient Leaflet]. Leeds, UK: Rosemont Pharmaceuticals Limited; 2019.
- MedlinePlus. Acetaminophen.
- Offringa M, Newton R, Cozijnsen MA, et al. Prophylactic drug management for febrile seizures in children. Cochrane Database Syst Rev. 2017;2(2):CD003031.
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 635-36.