Ontibal Syrup
Product Info
| Prescription required | Yes |
| Marketer | Balsons Pharmaceutical |
| Active Ingredient | Ondansetron (2mg/5ml) |
| Storage | Store below 30°C |
| Chemical Class | Carbazole Derivative |
| Habit Forming | No |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Serotonin antagonists (5-HT3 antagonists) |
| User Rating | 4.4 |
| User Reviews | 590 |
FAQ
What is Ontibal used for?
Ontibal is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give Ontibal to your child to prevent vomiting post-procedure. Apart from this, Ontibal is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Ontibal to your child for a few days. Stick to the dose for best results.
My child is having a migraine and is on medication. Can I give Ontibal along with it?
Avoid combining Ontibal with such medicines because concomitant use of Ontibal with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.
How should Ontibal be stored?
Ontibal should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.
Can other medicines be given at the same time as Ontibal?
Ontibal can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Ontibal. Also, check with your child’s doctor before giving any medicine to your child.
In what conditions do I need to call my child’s doctor right away?
Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.
What if my child takes too much Ontibal?
Ontibal is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Ontibal can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.
What if you forget to take Ontibal?
Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
Ontibal Syrup Reviews
Ontibal is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.
Ontibal may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double dose if it is already time for the next dose.
Ontibal may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.
Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.
How Ontibal Syrup Works
During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Ontibal just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.
How to Use Ontibal Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ontibal may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Ontibal Syrup
- In Treatment of Nausea: Ontibal blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused by cancer chemotherapy and radiation treatment (in adults and children aged 4 years and older). It is usually taken both before and after chemotherapy or radiation. This medicine helps you recover more comfortably from these treatments. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.
Uses of Ontibal Syrup
- Treatment of Nausea
- Vomiting
Ontibal Syrup Side Effects
Safety Tips
Kidney
SAFE IF PRESCRIBED
Ontibal is safe to use in patients with kidney disease. No dose adjustment of Ontibal is recommended.
Pregnancy
SAFE IF PRESCRIBED
Ontibal is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving
SAFE
Ontibal does not usually affect your ability to drive.
Breast feeding
SAFE IF PRESCRIBED
Ontibal is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Liver
CAUTION
Ontibal should be used with caution in patients with liver disease. Dose adjustment of Ontibal may be needed. Please consult your doctor.In severe liver disease, do not exceed the prescribed dose and consult your child’s doctor.
Alcohol
SAFE
Consuming alcohol with Ontibal does not cause any harmful side effects.
Quick Tips
- Practice self-care measures:Give plenty of fluids to your child to avoid dehydrationAvoid giving fried and spicy food or heavy meals to your child. Ensure that your child eats slowly and in small proportions.
- It is fast-acting and starts working within 30 minutes.
- Ontibal effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
References
- Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
- Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran).
- Ondansetron [Summary of Product Characteristics]. Solan, Himachal Pradesh: Cachet Pharmaceuticals PVT. LTD.; 2024.
- Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
- Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016.