Signopara 250mg Syrup
Product Info
| Prescription required | No |
| Marketer | Capcure Pharmaceuticals |
| Active Ingredient | Paracetamol (250mg) |
| Salt Synonyms | Acetaminophen |
| Storage | Store below 30°C |
| Chemical Class | P-Aminophenol Derivative |
| Habit Forming | No |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Analgesic & Antipyretic-PCM |
| User Rating | 4.5 |
| User Reviews | 460 |
FAQ
Can I give Signopara 250mg on a routine basis when my child is taking a vaccine?
Signopara 250mg usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, it is best if you let your child recover from the ongoing illness and finish the course of the medicine As soon as a child is feeling better the vaccine can and should be given.
My child vomited after taking Signopara 250mg. What should I do?
If your child vomits within 30 minutes of taking Signopara 250mg, repeat the dose again. If it has been more than 30 minutes after taking Signopara 250mg and your child vomits, no need to repeat the dose and wait until it is time for the next dose. If you are not sure, consult your doctor.
Is there any special diet my child needs to follow while taking this medicine?
Unless instructed by your doctor, your child should take a normal balanced diet while continuing this medicine as lack of nutrition can put your child at risk of developing medicinal toxicity.
How much of Signopara 250mg is considered as an overdose?
You should only take four doses of Signopara 250mg in 24 hours. There should be a gap of at least 4-6 hours between two doses. Do not take it for more than 3 days without first talking to your doctor. Based on the dose, more than 250 mg/kg can lead to toxicity and can be potentially fatal. An overdose is capable of causing serious damage to the liver and kidneys. Inform your doctor immediately if you think you have given too much of this medicine to your child, even if your child seems well, because of the risk of delayed, serious liver damage.
When will my child’s condition improve after taking Signopara 250mg?
Signopara 250mg usually starts working within 30 to 60 mins of intake and shows its peak effect within 3 to 4 hours. Your child may start to feel better after a few doses. In case the pain or fever persists longer, consult your child’s doctor immediately.
Where should I store this medicine?
Keep this medicine at room temperature in a dry place beyond the reach of the children.
Can I give Signopara 250mg to my child for low-grade fever?
You can give this medicine if your child has a temperature of 38.3°C (101°F) or higher. But, you must always try to speak to your child’s doctor first.
How much Signopara 250mg should I give to my child?
Always follow your doctor's instructions regarding how much of the medicine to give and how often to give it. This depends on the strength of the medicine and the age of your child. You may also check the label or the leaflet inside the packaging for directions before use. The commonly recommended dose is 10-15 mg/kg per dose every 4 to 6 hours. In case you are not sure how much to give, consult your child’s doctor.
My child’s fever is persistent even after taking Signopara 250mg. What should I do?
If the fever doesn't come down after the initial few doses, the cause might be an infection (virus or bacteria). It is advised to consult your child’s doctor for specific treatment.
In what conditions Signopara 250mg must be given with caution?
It is advised to use Signopara 250mg with caution if the child has malnutrition, G6PD deficiency, liver disease, or any medicinal allergy. So, do not hesitate to share your child’s complete medical history with the doctor as that will help the doctor decide whether the medicine is safe for your child or not.
What if you forget to take Signopara Syrup?
Do not panic. Unless your doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember it. Skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
Signopara 250mg Syrup Reviews
Signopara 250mg is a widely prescribed medicine that helps to ease pain and bring down high body temperature (fever). In children, it treats conditions like headache, toothache, body ache, fever, and common cold.
Signopara 250mg is given orally preferably at a fixed time every day. Though this medicine can be taken before or after food, it is best given after food as it can irritate the inner lining of an empty stomach. The dose and duration will depend upon your child’s age, body weight, and severity of the infection, so stick to the dose, time, and way prescribed by your child’s doctor. If your child vomits within 30 minutes of taking the medicine, let the child calm down and repeat the same dose. Redosing is not recommended if your child gets sick more than 30 minutes after taking a dose.
Do not give your child Signopara 250mg along with other medicines (many cold and flu medicines and other painkillers) that contain paracetamol, as this may result in overdosing and cause dangerous side effects such as hepatotoxicity (liver damage). Always check the ingredients of any other medicines before giving them to your child in combination with this medicine.
Generally, this medicine is well-tolerated by the children. However, temporary side effects such as indigestion, nausea, vomiting, and difficulty in sleeping, may occur in some children. Consult your doctor in case these episodes become bothersome for your child.
This medicine is often considered safe and effective but may not be suitable for everybody. Inform your doctor if your child is undergoing treatment for any blood-related disorder, is allergic to any medicinal compound, or has any birth defects, liver impairment, or kidney dysfunction. This will help your child’s doctor evaluate the dose and suitability of this medicine in a better way.
How Signopara 250mg Syrup Works
Signopara 250mg possesses analgesic (pain-reliever) and antipyretic (lowers body temperature) properties. It provides relief by blocking certain chemical messengers and pathways in the brain that send signals about pain and fever.
How to Use Signopara 250mg Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Signopara 250mg is to be taken with food.
Benefits of Signopara 250mg Syrup
- In Treatment of Fever: Signopara 250mg is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.
- In Pain relief: Signopara 250mg is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage. Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. It is also the first choice of painkiller during pregnancy or breastfeeding.
Uses of Signopara 250mg Syrup
- Treatment of Fever
- Pain relief
Signopara 250mg Syrup Side Effects
Safety Tips
Alcohol
UNSAFE
It is unsafe to consume alcohol with Signopara 250mg.
Driving
SAFE
Signopara 250mg does not usually affect your ability to drive.
Kidney
CAUTION
Signopara 250mg should be used with caution in patients with severe kidney disease. Dose adjustment of Signopara 250mg may be needed. Please consult your doctor.However, Signopara 250mg contains paracetamol which is considered the safest painkiller for children with kidney disease.
Pregnancy
SAFE IF PRESCRIBED
Signopara 250mg is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Liver
CAUTION
Signopara 250mg should be used with caution in patients with liver disease. Dose adjustment of Signopara 250mg may be needed. Please consult your doctor.However, the use of Signopara 250mg is not recommended in children with severe liver disease and active liver disease.
Breast feeding
SAFE IF PRESCRIBED
Signopara 250mg is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Quick Tips
- Give Signopara 250mg to your child with food or milk to prevent an upset stomach.
- Your child should not take more than four doses of this medicine in 24 hours, so wait up to 6 hours between doses.
- If Signopara 250mg does not seem to be helping your child, contact your doctor for advice. Do not give extra doses.
- Inform the doctor if your child has liver disease as the dose may need to be adjusted.
- Never give any other medicine formulation containing paracetamol along with this medicine as that may lead to serious side effects.
References
- MedlinePlus. Acetaminophen.
- Royal College of Paediatrics and Child Health. Medicines for Children - information for parents and carers.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
- Section on Clinical Pharmacology and Therapeutics; Committee on Drugs, Sullivan JE, Farrar HC. Fever and antipyretic use in children. Pediatrics. 2011;127(3):580-7.
- Aabideen K, Moulton LS, Sills J. Accidental staggered paracetamol overdose: An interesting case report. J Pharmacol Pharmacother. 2011;2(3):189-190.
- Paracetamol [EMC Patient Leaflet]. Leeds, UK: Rosemont Pharmaceuticals Limited; 2019.
- Kids Health. Safe Use Of Paracetamol In Children.
- Children’s Health Queensland Hospital and Health Service. Emergency care of children: Medication guides for use in Queensland.
- Acetaminophen [Prescribing Information]. lake Zurich, IL: Fresenius Kabi USA, LLC; 2015.
- Grosser T, Smyth E, FitzGerald G. Pharmacotherapy of Inflammation, Fever, Pain, and Gout. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018.