AF 400 Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Systopic Laboratories Pvt Ltd
Active Ingredient	Fluconazole (400mg)
Storage	Store below 30°C
Chemical Class	Azole derivatives {Imidazoles}
Habit Forming	No
Therapeutic Class	ANTI INFECTIVES
Action Class	Fungal ergosterol synthesis inhibitor
User Rating	4.4
User Reviews	520

FAQ

What is AF 400 used for?

AF 400 is an antifungal medicine. It is used for the treatment of many fungal infections like Cryptococcal meningitis (fungal infection in the brain) and Coccidioidomycosis (a disease of the lungs). Additionally, it is helpful in the treatment of infections caused by Candida found in the bloodstream, body organs (e.g., heart, lungs) or urinary tract, mucosal thrush (infection affecting the lining of the mouth, throat, and denture sore mouth), and genital thrush (infection of the vagina or penis). It can also be used to treat skin infections like athlete's foot, ringworm, jock itch, nail infection.

Does AF 400 treat urinary tract infection (UTI)?

AF 400 is used to treat urinary tract infections (UTI) caused mainly by Candida. However, bacteria growth can also cause UTI in some cases. If you are suffering from UTI, please consult your doctor as the cause of infection (fungal or bacterial, or other) needs to be identified before the start of any treatment.

I feel better now, can I stop taking AF 400?

No, you should not stop taking AF 400 suddenly without consulting your doctor. This is because suddenly stopping the medication may worsen your condition and your infection may return. Continue your medication even if you feel better as your symptoms may improve before the infection is completely cleared. Stopping the medication too early could allow the fungus to continue to grow and hence, prevent complete healing.

Is AF 400 effective?

Yes, AF 400 is effective when used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using AF 400 too early, the symptoms may return or worsen.

Is AF 400 a steroid?

No, AF 400 is not a steroid. AF 400 belongs to a group of medicines called antifungals.

Does AF 400 make you feel tired?

Yes, AF 400 can make you feel tired. If you experience excessive tiredness during the treatment with this medicine, consult your doctor. The reason for tiredness could be a sign of an underlying liver problem as AF 400 can affect your liver.

Does AF 400 treat bacterial vaginosis?

No, AF 400 does not treat bacterial vaginosis as it is not active against any bacteria. AF 400 is used to treat infection of the vagina caused by Candida (a fungal infection). If you think you are suffering from bacterial vaginosis, consult your doctor. This is because the diagnosis of your infection (whether it is fungal or bacterial) is required to start your treatment.

Is AF 400 fungistatic or fungicidal?

AF 400 is primarily fungistatic which means it controls the growth of fungus). However, it may also act as a fungicidal (kills fungus) medicine against certain organisms, specifically Cryptococcus in a dose-dependent manner, specifically Cryptococcus.

Can I take AF 400 with alcohol?

Yes, AF 400 can be taken with alcohol. No interactions have been reported between the two. However, it is better to consult your doctor on the use of alcohol before taking AF 400 to avoid any side effects and get the maximum benefit of AF 400.

Can I take AF 400 for yeast infection?

Yes, AF 400 can be used for the treatment of yeast (candidal) infection. However, if you think you are suffering from a yeast infection, consult your doctor. This is because proper diagnosis is required before starting any therapy.

Can AF 400 cause hair loss?

AF 400 may cause hair loss as a rare side effect. If during the treatment you experience hair loss, inform your doctor.

Is AF 400 over the counter (OTC)?

No, AF 400 is not an over-the-counter (OTC) product. It is available only when prescribed by your doctor.

Can AF 400 be taken with oral contraceptives (OCPs) or birth control pills?

AF 400 has been reported to have a minor interaction when taken with estradiol (a component of oral contraceptives). It can increase the level or effect of estradiol when given along with it. Before starting the treatment with AF 400 inform your doctor if you are taking birth control pills.

Is AF 400 safe to be used in pregnancy?

No, AF 400 is not safe to be used in pregnancy. Studies suggest that the use of AF 400 during pregnancy is harmful to the development of the baby. Therefore, AF 400 is prescribed in pregnant women only if the benefits of the medicine outweigh the risks involved. However, if a woman gets pregnant during the treatment with AF 400, she must be well informed about the potential harm to the baby. If you are planning to conceive, are pregnant, or breastfeeding, inform your doctor before taking AF 400.

What if I forget to take a dose of AF 400?

If you have missed a dose of AF 400, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

What if you forget to take AF Tablet?

If you miss a dose of AF 400, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

AF 400 Tablet Reviews

AF 400 is used to treat fungal infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane thereby stopping the growth of fungi.

AF 400 should be taken in the dose and duration as prescribed by your doctor. It should be swallowed whole and can be taken with or without food. The dosage and length of treatment will depend on the condition you are being treated for. Sometimes this will be in cycles of use and non-use. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse. Avoid taking antacid treatments within one hour before or two hours after you take it.

The most common side effects of this medicine include stomach pain, vomiting, diarrhea, rash, headache, and nausea. You could ask your doctor about ways of preventing or reducing these effects. Stop taking medicine and inform your doctor if you notice signs of an allergic reaction such as rash, swelling of the lips, throat, or face, swallowing or breathing problems, dizziness, and nausea.

Do not take AF 400 if you are pregnant unless your doctor has told you to. Inform your doctor if you have a history of heart failure, a weak immune system (including HIV/AIDS), kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may monitor your liver function. This medicine may make you dizzy so do not drive or operate machines until it is safe.

How AF 400 Tablet Works

AF 400 is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.

How to Use AF 400 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. AF 400 may be taken with or without food, but it is better to take it at a fixed time.

Benefits of AF 400 Tablet

In Treatment of Fungal infections: AF 400 is an antifungal medicine. It works by killing and stopping the growth of fungi that causes the infection. It helps treat infections of the mouth, throat, vagina, and other parts of the body.The dose and duration of treatment will depend on what you are being treated for. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.

Uses of AF 400 Tablet

Treatment of Fungal infections

AF 400 Tablet Side Effects

Safety Tips

Driving ^UNSAFE

AF 400 may cause side effects which could affect your ability to drive.AF 400 may cause dizziness or seizures. This may affect your ability to drive.

Breast feeding ^{CONSULT YOUR DOCTOR}

AF 400 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Kidney ^UNSAFE

AF 400 is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.Caution to be advised in patients with impaired renal function.

Pregnancy ^{CONSULT YOUR DOCTOR}

AF 400 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Alcohol ^CAUTION

Caution is advised when consuming alcohol with AF 400. Please consult your doctor.

Liver ^CAUTION

AF 400 should be used with caution in patients with liver disease. Dose adjustment of AF 400 may be needed. Please consult your doctor.

Quick Tips

Your doctor has prescribed AF 400 to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Inform your doctor if you develop severe skin rash like blistering of the skin along with fever.
Use a reliable method of contraception to prevent pregnancy while taking this medicine.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

References

Medsacpe. Fluconazole.
Fluconazole [Patient Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2022.
Fluconazole. New York, New York: Pfizer; 2014.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98.
Central Drugs Standard Control Organisation (CDSCO).
Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1579-80.
Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 840-41.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 551-54.