Apraize 10mg Tablet


Product Info

Prescription required Yes
Marketer Ipca Laboratories Ltd
Active Ingredient Apremilast (10mg)
Storage Store below 30°C
Chemical ClassIsoindole Derivative
Habit FormingNo
Therapeutic ClassPAIN ANALGESICS
Action ClassPhosphodiesterase-IV inhibitors (PsA & PSO)
User Rating4.6
User Reviews439

FAQ

Question
How long does it take for Apraize 10mg to work?
Apraize 10mg is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-term treatment and may take about 16 weeks to show an improvement.
Answer

Question
Can Apraize 10mg cause depression?
Yes, Apraize 10mg may cause depression as a side effect. The patient may also develop suicidal thoughts. It should be avoided in patients with a history of depression. In case you develop any of these symptoms, consult your doctor immediately or ask your friends or relatives to help seek medical advice.
Answer

Question
Is Apraize 10mg an immunosuppressant?
No, Apraize 10mg is not an immunosuppressant. It belongs to a class of medicines known as phosphodiesterase 4 inhibitors (PDE4) which work by blocking the activity of PDE4. PDE4 is found in inflammatory cells and blocking it helps in reducing the molecules responsible for inflammation.
Answer

Question
Can I take rifampicin along with Apraize 10mg?
You should not take rifampicin if you are taking Apraize 10mg. Rifampicin interferes with the working of Apraize 10mg by decreasing its levels, making it less effective. As a result, you may not see any improvement after taking Apraize 10mg.
Answer

Question
How should Apraize 10mg be taken?
Be sure to take Apraize 10mg exactly as directed by your doctor. Your doctor will prescribe a low dose initially. This dose will be increased gradually after 6 days. Swallow the tablets whole with water. You can take it with or without food.
Answer

Question
What if I get pregnant during treatment with Apraize 10mg?
In case you get pregnant while taking Apraize 10mg, you should inform your doctor immediately. In fact, pregnancy should be avoided during treatment with this medicine. The reason being, according to animal studies, with Apraize 10mg there may be a risk of baby loss or defects in unborn baby.
Answer

Question
Does Apraize 10mg cause weight reduction?
Yes, Apraize 10mg may cause a decrease in appetite which may further cause weight loss. You should monitor your weight regularly while on treatment with Apraize 10mg. In case of significant weight loss, consult your doctor and consider stopping Apraize 10mg.
Answer
Question
What if you forget to take Apraize Tablet?
If you miss a dose of Apraize 10mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Apraize 10mg Tablet Reviews

Apraize 10mg is used in the treatment of moderate to severe plaque psoriasis which is a type of skin condition. This medicine is used when other conventional treatments cannot be used or if the patient is not responsive or intolerant to any of these treatments.

Apraize 10mg can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. You may need to monitor your weight regularly while taking the medicine as it may cause weight loss.

Using this medicine may cause few common side effects such as nausea, diarrhea, vomiting, headache, and upper respiratory tract infection. If these side effects persist or get worse, let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.

How Apraize 10mg Tablet Works

Apraize 10mg is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms of these conditions.

How to Use Apraize 10mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apraize 10mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Apraize 10mg Tablet

  • In Plaque psoriasis: Plaque psoriasis is the most common form of psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Apraize 10mg reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Uses of Apraize 10mg Tablet

  • Plaque psoriasis

Apraize 10mg Tablet Side Effects

Item form

Safety Tips

Liver  SAFE IF PRESCRIBED
Apraize 10mg is safe to use in patients with liver disease. No dose adjustment of Apraize 10mg is recommended.
Pregnancy  CONSULT YOUR DOCTOR
Apraize 10mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Apraize 10mg during breastfeeding is not available. Please consult your doctor.
Kidney  CAUTION
Apraize 10mg should be used with caution in patients with severe kidney disease. Dose adjustment of Apraize 10mg may be needed. Please consult your doctor.
Alcohol  CAUTION
Caution is advised when consuming alcohol with Apraize 10mg. Please consult your doctor.
Driving  CONSULT YOUR DOCTOR
It is not known whether Apraize 10mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Quick Tips

  • Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss. 
  • Apraize 10mg is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
  • Monitor your weight regularly as Apraize 10mg may cause weight loss.
  • Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.

References

  1. Apremilast [Prescribing Information]. Thousand Oaks, CA: Amgen Inc.; 2021.
  2. National Drug Monograph. Apermilast; 2015.
  3. Medscape. Apremilast.

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