Barinat 4 Tablet


Product Info

Prescription required Yes
Marketer Natco Pharma Ltd
Active Ingredient Baricitinib (4mg)
Storage Store below 30°C
Chemical ClassPyrrolo Pyrimidine Derivative
Habit FormingNo
Therapeutic ClassPAIN ANALGESICS
Action ClassJanus kinase inhibitors
User Rating4.4
User Reviews737

FAQ

Question
Do I need to get any investigations done before starting Barinat 4?
You may need to get your blood tests done before you start Barinat 4 or while you are taking it. Blood tests are done in order to check if you have a low red blood cell count (anemia), low white blood cell count (neutropenia or lymphopenia), high blood fat (cholesterol) or high levels of liver enzymes. It also helps to ensure that treatment with Barinat 4 is not causing problems. In addition to this, your doctor may advise you to get tested for tuberculosis before starting Barinat 4, as using Barinat 4 may make an existing infection worse.
Answer

Question
Can Barinat 4 cause cancer?
Barinat 4 may increase the chances of developing the risk of certain cancers (lymphoma and other cancers including skin cancers) by affecting the working of the immune system. Hence, inform your doctor if you ever had or have any type of cancer.
Answer

Question
Can I take Barinat 4 if I have liver problems?
Inform your doctor if you have liver problems, before starting Barinat 4. This is done because in some cases Barinat 4 may cause an increase in liver enzymes. Therefore, your liver function needs to be investigated before starting Barinat 4. Although, Barinat 4 can be given to patients with mild to moderate liver function impairment, but should not be prescribed to patients with severe liver impairment.
Answer

Barinat 4 Tablet Reviews

Barinat 4 is used in combination with Remdesivir for the treatment of coronavirus disease (COVID-19) in hospitalized adults.

Barinat 4 can be taken with or without food, but it is best to take them at the same time each day. Your dose will depend on your condition and what other medicines you are taking. You should use it as your doctor tells you to. Do not stop taking this medicine unless your doctor tells you to because your condition could get worse.

The most common side effects of Barinat 4 include throat and nose infections, nausea, and viral infection. You may also get cold sores, a feeling of sickness, or have symptoms of a cold like stuffy nose, sneezing, and sore throat. There are other less common side effects, some of them serious, including blood clots and tears in the stomach or intestine wall. These need urgent medical attention. If you have concerns regarding side effects, talk to your doctor.

You may need blood tests before you are given this medicine and you should not start taking it if you have any kind of infection. Make sure you talk to your doctor before starting treatment if you have or have ever had, tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Barinat 4 can make you more likely to get infections or may worsen any current infections so avoid contact with people who have things you might catch (e.g., chickenpox, measles or flu). This medicine is not suitable for children under 18 years old and you should not use it if you’re pregnant or breastfeeding, unless your doctor feels the benefit is greater than the risk. Your doctor may need to examine you on a regular basis.

How Barinat 4 Tablet Works

Barinat 4 is a Janus kinase (JAK) inhibitor that inhibits the activity of selective JAK1 and JAK2 enzymes, which interfere with the JAK-STAT signaling pathway (a chain of protein-cell interactions, involved in processes such as immunity, cell division, cell death, and tumor formation).

How to Use Barinat 4 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Barinat 4 may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Barinat 4 Tablet

  • In Treatment of Coronavirus disease (COVID-19): Coronavirus disease (Covid-19) is a highly infectious disease caused by a coronavirus strain named SARS-CoV2. The most common symptoms are fever, cough, loss of taste or smell, breathing difficulty, nasal congestion, and diarrhea among others. Barinat 4 helps alleviate these symptoms but must be used only under medical supervision.

Uses of Barinat 4 Tablet

  • Treatment of Coronavirus disease (COVID-19)

Barinat 4 Tablet Side Effects

Item form

Safety Tips

Kidney  UNSAFE
Barinat 4 is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Pregnancy  CONSULT YOUR DOCTOR
Barinat 4 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Driving  SAFE
Barinat 4 does not usually affect your ability to drive.
Liver  SAFE IF PRESCRIBED
Barinat 4 is safe to use in patients with liver disease. No dose adjustment of Barinat 4 is recommended.Barinat 4 may not be recommended in patients with severe liver disease due to lack of information and research. Therefore, it is important to consult the doctor.
Breast feeding  CONSULT YOUR DOCTOR
Barinat 4 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alcohol  SAFE
Consuming alcohol with Barinat 4 does not cause any harmful side effects.

Quick Tips

  • Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts or cholesterol level.
  • Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

References

  1. Baricitinib [Product Label]. Eli Lilly and Company; 2020.
  2. Baricitinib. Indianapolis, Indiana: Lilly USA; 2018.
  3. Eli Lilly and Company. Olumiant (baricitinib).
  4. Drugs.com. Baricitinib.
  5. Medscape. Baricitinib.

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