Brexlene 10mg Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Zee Laboratories
Active Ingredient	Methoxsalen (10mg)
Storage	Store below 30°C
Chemical Class	Psoralens Derivative
Habit Forming	No
Therapeutic Class	DERMA
Action Class	Psoralen & derivatives
User Rating	4.4
User Reviews	629

FAQ

What is Brexlene 10mg used for?

Brexlene 10mg is used along with ultraviolet light (found in sunlight and some special lamps) in a treatment to treat vitiligo (a disease in which skin color is lost), and psoriasis (a skin condition associated with red and scaly patches), and treatment of white blood cells (called photopheresis) and is used to treat the skin problems associated with mycosis fungoides, which is a type of lymphoma

How does Brexlene 10mg work?

Brexlene 10mg works by modifying the way by which skin cells receive the ultraviolet light A (UVA) radiation, thereby clearing up the disease.

What if you forget to take Brexlene Tablet?

If you miss a dose of Brexlene 10mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Brexlene 10mg Tablet Reviews

Brexlene 10mg is a medicine used along with controlled ultraviolet light for effective treatment of certain skin diseases like vitiligo and psoriasis.

Brexlene 10mg is taken after meals in a dose and duration as advised by the doctor. Taking with food helps to increase the absorption of the medication as well as decrease nausea. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects of Brexlene 10mg are nausea, itching, and redness of the skin. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make dizziness worse.

Taking this medicine makes the skin more sensitive to the sun. Use sunscreen and wear protective clothing when outdoors. Try to avoid exposure of your skin and lips to sunlight for eight hours after treatment.

How Brexlene 10mg Tablet Works

Brexlene 10mg is an organic compound. It is used along with ultraviolet-A irradiation. It works by decreasing the number of cells the skin makes.

How to Use Brexlene 10mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Brexlene 10mg is to be taken with food.

Benefits of Brexlene 10mg Tablet

In Psoriasis: Psoriasis is a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Brexlene 10mg reduces the scaly, itchy patches along with other symptoms of inflammation such as redness, swelling, or irritation which may develop on the different parts of the body. Use it for as long as it is prescribed to get the most benefit. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Vitiligo: Vitiligo is a condition in which the skin loses its natural color in patches. Brexlene 10mg effectively blocks that process in the skin that leads to discoloration. It also reduces any redness, rash, pain, or itchiness that may be caused by this condition. This improves your self-esteem and confidence as your appearance changes. You should always take it as prescribed to get the full benefits.

Uses of Brexlene 10mg Tablet

Psoriasis
Vitiligo

Brexlene 10mg Tablet Side Effects

Safety Tips

Kidney ^{CONSULT YOUR DOCTOR}

There is limited information available on the use of Brexlene 10mg in patients with kidney disease. Please consult your doctor.

Driving ^{CONSULT YOUR DOCTOR}

It is not known whether Brexlene 10mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Alcohol ^{CONSULT YOUR DOCTOR}

It is not known whether it is safe to consume alcohol with Brexlene 10mg. Please consult your doctor.

Pregnancy ^{CONSULT YOUR DOCTOR}

Brexlene 10mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding ^CAUTION

Brexlene 10mg should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Liver ^CAUTION

Brexlene 10mg should be used with caution in patients with liver disease. Dose adjustment of Brexlene 10mg may be needed. Please consult your doctor.

Quick Tips

Take a plain shower before your treatment to keep your skin clean, and pat dry.
Always take Brexlene 10mg 2 hours before UV radiation exposure along with food or milk.
Use extra caution for at least 48 hours following each treatment. After each treatment, cover your skin for at least 8 hours by wearing protective clothing.
Take this treatment (methoxsalen and UVA) two or three times a week with the treatment spaced at least forty-eight hours apart.
Brexlene 10mg is prescribed along with UV-A rays for the treatment of vitiligo and psoriasis.
Never take Brexlene 10mg more than the prescribed dose as it may cause burning or blistering of your skin after exposure to UV light.
Do not use perfumes, aftershave, deodorants or other cosmetics and toiletries while using Brexlene 10mg as they make your skin even more sensitive causing blistering of your skin.

References

Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1055.
ScienceDirect. Methoxsalen.
Methoxsalen [patient Information]. Bengaluru, India: Strides Pharma Science Ltd.; 2019.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 891-92.
PubChem. Methoxsalen.
Central Drugs Standard Control Organisation (CDSCO).
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1813-14.