Busuphan 2mg Tablet
Product Info
| Prescription required | Yes |
| Marketer | Elder Pharmaceuticals Ltd |
| Active Ingredient | Busulfan (2mg) |
| Storage | Store below 30°C |
| Chemical Class | Organosulfonic Acid Esters Derivative {Alkylating Agent |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkylating agent |
| User Rating | 4.7 |
| User Reviews | 303 |
FAQ
Is Busuphan 2mg a vesicant?
Yes. Busuphan 2mg is a vesicant (irritant).
Does Busuphan 2mg cause hair loss?
Yes, Busuphan 2mg can cause hair loss.
What if you forget to take Busuphan Tablet?
If you miss a dose of Busuphan 2mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Busuphan 2mg Tablet Reviews
Busuphan 2mg is used in the treatment of some cancers of blood like chronic myeloid leukaemia. It is used in combination with other cancer medicines during hematopoietic progenitor cell transplantation (HPCT). It may also be used to treat some other types of cancer.
Busuphan 2mg can be taken with or without food, but better to take it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include decreased blood cells (red cells, white cells, and platelets), nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Busuphan 2mg can be taken with or without food, but better to take it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include decreased blood cells (red cells, white cells, and platelets), nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
How Busuphan 2mg Tablet Works
Busuphan 2mg is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
How to Use Busuphan 2mg Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Busuphan 2mg may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Busuphan 2mg Tablet
- In Blood cancer (Chronic myeloid leukaemia): Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Busuphan 2mg kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Uses of Busuphan 2mg Tablet
- Blood cancer (Chronic myeloid leukaemia)
Busuphan 2mg Tablet Side Effects
- Stomatitis (Inflammation of the mouth)
- Decreased magnesium level in blood
- Increased glucose level in blood
- Decreased blood cells (red cells, white cells, and platelets)
- Decreased potassium level in blood
- Fever
- Headache
- Abdominal pain
- Insomnia (difficulty in sleeping)
- Loss of appetite
- Anxiety
- Vomiting
- Nausea
- Diarrhea
Safety Tips
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Busuphan 2mg. Please consult your doctor.
Kidney
SAFE IF PRESCRIBED
Busuphan 2mg is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Busuphan 2mg may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Busuphan 2mg in patients with liver disease. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Busuphan 2mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Pregnancy
CONSULT YOUR DOCTOR
Busuphan 2mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Busuphan 2mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Quick Tips
- Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Take it at a same time every day, either with food or without food.
- Do not skip any dose and complete the course as suggested by your doctor.
- Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
References
- Busulfan. Ireland: Aspen Pharma Trading Limited; 13 Jan. 1986 [revised Sep. 2017].
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Busulfan. [Updated 2018 Oct 31].
- Drugs.com. Busulfan Pregnancy and Breastfeeding Warnings.
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1685-86.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 171-72.