Certican 0.5 Tablet
Product Info
| Prescription required | Yes |
| Marketer | Novartis India Ltd |
| Active Ingredient | Everolimus (0.5mg) |
| Storage | Store below 30°C |
| Chemical Class | Macrolide Lactams |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Immunosuppressant- mTOR inhibitors |
| User Rating | 4.2 |
| User Reviews | 595 |
FAQ
Is any monitoring required while taking Certican 0.5?
Regular monitoring is required while you are on Certican 0.5. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Certican 0.5. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
How will I know that Certican 0.5 is shrinking my brain tumor?
The effect of Certican 0.5 in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
How is Certican 0.5 administered?
Usually, Certican 0.5 is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Certican 0.5 should be swallowed whole with water and should not be crushed or chewed.
Is Certican 0.5 cytotoxic?
Yes, Certican 0.5 is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
Is Certican 0.5 a chemotherapy?
Certican 0.5 is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
What is the most important information I need to know about Certican 0.5?
Certican 0.5 can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
What should I avoid while taking Certican 0.5?
You should avoid grapefruit or grapefruit juice while taking Certican 0.5. This is because taking them together may increase the levels of Certican 0.5 in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
How long can you take Certican 0.5?
There is no definite duration of treatment with Certican 0.5. Certican 0.5 is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Certican 0.5 Tablet Reviews
Certican 0.5 is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ. It is also used in combination with other medicines to treat cancers of breast, pancreas, lungs, and kidney.
Certican 0.5 must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.
The common side effects of this medicine include infection, fever, cough, fatigue, diarrhea, and upper respiratory infection. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough or fever, or need to receive any vaccination after taking this medication.
Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. It may affect male or female fertility, so consult the doctor if you are planning to have a child.
How Certican 0.5 Tablet Works
Certican 0.5 suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
How to Use Certican 0.5 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Certican 0.5 may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Certican 0.5 Tablet
- In Prevention of organ rejection in transplant patients: Certican 0.5 is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.
Uses of Certican 0.5 Tablet
- Prevention of organ rejection in transplant patients
Certican 0.5 Tablet Side Effects
Safety Tips
Kidney
SAFE IF PRESCRIBED
Certican 0.5 is safe to use in patients with kidney disease. No dose adjustment of Certican 0.5 is recommended.
Liver
CAUTION
Certican 0.5 should be used with caution in patients with liver disease. Dose adjustment of Certican 0.5 may be needed. Please consult your doctor.Use of Certican 0.5 is not recommended in patients with severe liver disease.
Pregnancy
CONSULT YOUR DOCTOR
Certican 0.5 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Certican 0.5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Certican 0.5. Please consult your doctor.
Driving
UNSAFE
Certican 0.5 may cause side effects which could affect your ability to drive.As fatigue is a common side effect with Certican 0.5 and this may affect your ability to drive
Quick Tips
- If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Certican 0.5.
- Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Certican 0.5 increases your risk of getting an infection.
- Certican 0.5 may affect male or female fertility; consult your doctor if you are planning to have a child.
- While you are taking Certican 0.5 do not take any vaccinations without talking to your doctor first.
- Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Certican 0.5.
- Certican 0.5 is given for the treatment of certain cancers and to prevent organ transplant rejection.
References
- Everolimus [Prescribing Information]. Berkeley Heights: Hikma Pharmaceuticals USA Inc.; 2023.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 526.
- Everolimus. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Apr. 2018].
- Everolimus. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2011 [revised 12 Jul 2018].
- CiplaMed. Tacrolimus [Prescribing Information]. [Last Updated: 17 May 2021].
- Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1013.