Comig 500 Tablet


Product Info

Prescription required Yes
Marketer Seagull Pharmaceutical Pvt Ltd
Active Ingredient Naproxen (500mg) + Domperidone (10mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassPAIN ANALGESICS
User Rating4.2
User Reviews727

FAQ

Question
Can I stop taking Comig 500 when my migraine symptoms are relieved?
No, do not stop taking Comig 500 until advised by your doctor.
Answer

Question
What is Comig 500?
Comig 500 is a combination of two medicines: Naproxen and Domperidone. This combination helps in relieving the symptoms of migraine like headache, nausea and vomiting. Naproxen is a pain-killer that blocks the release of certain chemical messengers that cause headache. Domperidone is an anti-emetic agent (prokinetic). It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This helps in relieving vomiting.
Answer

Question
Can the use of Comig 500 cause damage to kidneys?
Yes, the long-term use of Comig 500 can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body, which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.
Answer

Question
Are there any specific contraindications associated with the use of Comig 500?
The use of Comig 500 is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.
Answer

Question
What are the recommended storage conditions for Comig 500?
Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Answer

Question
Can the use of Comig 500 cause diarrhea?
Yes, the use of Comig 500 can cause diarrhea. In case, you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting a doctor.
Answer

Question
Can I take a higher than the recommended dose of Comig 500?
No, taking a higher than the recommended dose of Comig 500 can increase the risks of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Answer
Question
What if you forget to take Comig Tablet?
If you miss a dose of Comig 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Comig 500 Tablet Reviews

Comig 500 is a combination of two medicines used in the prevention of migraines. It blocks the release of certain chemical messengers that cause pain, inflammation, and fever. It also blocks the signals in the brain that cause nausea and vomiting associated with migraines.

Comig 500 may be prescribed alone or in combination with another medicine. It can be taken with or without food. The dose and duration will depend on the severity of your condition and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.

Using of the medicine may cause few common side effects such as flu-like symptoms, indigestion, and dryness in the mouth. If you experience any such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholics or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

How Comig 500 Tablet Works

Comig 500 is a combination of two medicines: Naproxen and Domperidone. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain due to migraine. Domperidone is a prokinetic which works on the region in the brain that controls vomiting associated with migraine. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach.

How to Use Comig 500 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Comig 500 may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Comig 500 Tablet

  • In Prevention of Migraine: Comig 500 blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

Uses of Comig 500 Tablet

  • Prevention of Migraine

Comig 500 Tablet Side Effects

Item form

Safety Tips

Kidney  CAUTION
Comig 500 should be used with caution in patients with kidney disease. Dose adjustment of Comig 500 may be needed. Please consult your doctor.
Driving  UNSAFE
Comig 500 may cause side effects which could affect your ability to drive.Comig 500 may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Breast feeding  SAFE IF PRESCRIBED
Comig 500 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Pregnancy  CONSULT YOUR DOCTOR
Comig 500 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Comig 500.
Liver  CAUTION
Comig 500 should be used with caution in patients with liver disease. Dose adjustment of Comig 500 may be needed. Please consult your doctor.Use of Comig 500 is not recommended in patients with moderate and severe liver disease.

Quick Tips

  • It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Comig 500 affects you.
  • Get enough sleep and avoid stress
  • Avoid bright lights and extreme temperatures
  • Some tips that may help avoid a migraine attack:Have your meals at the same time everydayAvoid bright lights and extreme temperaturesAvoid loud music and noisy placesAvoid chocolates,  cheese, processed food, alcohol and smokingGet enough sleep and avoid stress
  • Avoid loud music and noisy places
  • Do not take it to treat an acute attack of migraine.
  • Avoid chocolates,  cheese, processed food, alcohol and smoking
  • You have been prescribed Comig 500 for prevention of migraine headaches.
  • Avoid consuming alcohol as it may cause new and worse headaches.
  • Have your meals at the same time everyday
  • Keep taking it every day, as prescribed by your doctor, even if you do not have any symptoms.

References

  1. Drugs.com. Domperidone.
  2. Naproxen. Nutley, New Jersey: Roche Laboratories Inc.
  3. Drugs.com. Naproxen.
  4. Domperidone and domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017].

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