D Zire 20mg Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Capital Pharma
Active Ingredient	Duloxetine (20mg)
Storage	Store below 30°C
Chemical Class	Naphthalene Derivative
Habit Forming	No
Therapeutic Class	NEURO CNS
Action Class	Serotonin-norepinephrine reuptake inhibitors (SNRIs)
User Rating	4.1
User Reviews	590

FAQ

What will be the consequences if I stop taking D Zire 20mg suddenly?

If you stop D Zire 20mg suddenly, you may feel dizzy, tired, agitated or restless, anxious and irritated. You may also experience sleep disturbances (vivid dreams, nightmares, inability to sleep), nausea, vomiting, shaking, muscle pain, diarrhea, a piercing sensation (pins and needles) especially in the head, and excessive sweating or vertigo. Always consult your doctor before you stop taking D Zire 20mg. Your doctor will reduce the dose gradually.

How long does D Zire 20mg take to work?

In people with depression and anxiety, D Zire 20mg mostly starts working within two weeks of treatment. However, you may take 2-4 weeks to feel better. Consult your doctor if you do not see any improvement after this time. In people with diabetic neuropathic pain, you may take a few weeks to feel better. Consult your doctor if you do not feel better after 2 months.

I am a hypertensive patient. I have noticed that my blood pressure has increased after I started taking D Zire 20mg. Is it because of D Zire 20mg, what should be done?

D Zire 20mg may cause an increase in blood pressure. Therefore, regular monitoring of blood pressure is required, especially during the first month of use. If your blood pressure increase is constant, consult your doctor. It may indicate that your D Zire 20mg dose either needs to be reduced or discontinued gradually.

I am taking warfarin, does D Zire 20mg interfere with warfarin? Is it safe to take both together?

You should be cautious if you are taking both D Zire 20mg and warfarin since there is a risk of bleeding or you may experience petechiae or purpura.

Is D Zire 20mg safe to use for long term?

D Zire 20mg is safe to use for a long duration, provided you follow your doctor’s advice regarding the treatment.

If I start feeling better, can I stop taking D Zire 20mg?

No, you should not stop D Zire 20mg suddenly and without consulting your doctor. In cases of depression and anxiety, if you have been feeling better for 6 months or more, your doctor may reduce your doses gradually. In case of pain and incontinence, if you are feeling better, continue taking it for the long term. Your doctor will keep monitoring your response to the medicine every few months.

Is D Zire 20mg highly addictive?

No, D Zire 20mg is not habit-forming (addictive). This means that it does not make you physically or psychologically dependent on it.

What if you forget to take D Zire Tablet?

If you miss a dose of D Zire 20mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

D Zire 20mg Tablet Reviews

D Zire 20mg is used in the treatment of depression, anxiety disorder, diabetic nerve pain, fibromyalgia (a condition in which there are generalized pain and tenderness in the body), neuropathic pain, and stress urinary incontinence.

D Zire 20mg works by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relax the nerves, thus treating your illness. It may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include nausea, headache, decreased libido, abnormal dreams, blurred vision, and dry mouth. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.

Before taking D Zire 20mg, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.

How D Zire 20mg Tablet Works

D Zire 20mg works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.

How to Use D Zire 20mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. D Zire 20mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of D Zire 20mg Tablet

In Treatment of Depression: D Zire 20mg increases the levels of certain chemicals in the brain that improve our mood and behavior. This creates a feeling of wellbeing, relieves anxiety, reduces tension, helps you sleep better, and increases your energy levels. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly, even if you feel better, as it may worsen your condition.
In Treatment of Stress urinary incontinence: Stress urinary incontinence refers to the loss of urine without conscious intention. It may occur due to a disturbed state of mind and thoughts. D Zire 20mg helps in increasing the activity of those nerves in the brain that control muscles in our bladder that are responsible for passing urine. This helps in improving bladder control.
In Treatment of Fibromyalgia: D Zire 20mg may also be used to treat pain in people with fibromyalgia. It reduces pain and also the mood changes, sleep problems, and tiredness that can be caused by the pain. It interferes with pain messages traveling through the brain. Taking this medicine regularly will have an impact on your overall quality of life. Keep taking the medicine until your doctor advises you to stop.
In Treatment of Neuropathic pain: D Zire 20mg is used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It interferes with pain signals that travel through the damaged nerves and the brain. Taking this medicine regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good.
In Treatment of Anxiety disorder: D Zire 20mg stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable, and sleep problems that often come with Anxiety Disorder. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
In Treatment of Diabetic nerve pain: High levels of blood sugar (glucose) levels in diabetic patients can cause damage to nerves and this can cause pain sensation. D Zire 20mg helps reduce this damage by affecting chemicals in the brain called neurotransmitters. By relieving pain, it helps improve your quality of life.

Uses of D Zire 20mg Tablet

Treatment of Neuropathic pain
Treatment of Stress urinary incontinence
Treatment of Anxiety disorder
Treatment of Depression
Treatment of Fibromyalgia
Treatment of Diabetic nerve pain

D Zire 20mg Tablet Side Effects

Safety Tips

Liver ^UNSAFE

D Zire 20mg is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Alcohol ^UNSAFE

It is unsafe to consume alcohol with D Zire 20mg.

Pregnancy ^{CONSULT YOUR DOCTOR}

D Zire 20mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Kidney ^CAUTION

D Zire 20mg should be used with caution in patients with severe kidney disease. Dose adjustment of D Zire 20mg may be needed. Please consult your doctor.

Breast feeding ^{CONSULT YOUR DOCTOR}

D Zire 20mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving ^UNSAFE

D Zire 20mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Quick Tips

Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
Avoid consuming alcohol when taking D Zire 20mg as it may cause excessive drowsiness and increase the risk of liver damage.
It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
D Zire 20mg helps in treating depression and anxiety.
It may take 2 to 4 weeks for D Zire 20mg to start working. Keep taking it as prescribed.
It may also be used to treat nerve pain from diabetes and some other forms of chronic pain.
Do not stop taking the medication suddenly without talking to your doctor.

References

Central Drugs Standard Control Organisation (CDSCO).
Stahl SM, editor. Duloxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 219-24.
Duloxetine Gastro-Resistant Tablets [Patient Information Sheet]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2022.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 442-43.
Duloxetine hydrochloride. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 09 Nov. 2018].
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Duloxetine. [Updated 2020 Jan 20].