Dulotop 25 Tablet
Product Info
| Prescription required | Yes |
| Marketer | Doxis Laboratories |
| Active Ingredient | Topiramate (25mg) |
| Storage | Store below 30°C |
| Chemical Class | Dioxolopyrans Derivative |
| Habit Forming | No |
| Therapeutic Class | NEURO CNS |
| Action Class | Sodium channel modulators (AED) |
| User Rating | 4.7 |
| User Reviews | 373 |
FAQ
Can Dulotop 25 be used in children?
Yes, Dulotop 25 is used for seizures in children more than 2 years of age. However, because of the lack of any reports, this medicine is not recommended to be used in children for migraines.
What are the serious side effects of Dulotop 25?
Serious side effects of Dulotop 25 are rare. The serious effects of Dulotop 25 may include glaucoma (difficulty in seeing, eye pain, and blurred vision), kidney stones (sharp pain in your sides or lower back), and metabolic acidosis (tiredness, loss of appetite, irregular and faint heartbeat). Other serious side effects of Dulotop 25 could be suicidal thoughts and insufficient sweating (some children taking Dulotop 25 may not sweat enough in hot weather, causing their body temperatures to rise).
Is Dulotop 25 good for anxiety?
Dulotop 25 is not indicated for the treatment of anxiety. Please consult your doctor before taking the medicine.
I am taking valproic acid for fits. Will Dulotop 25 interfere with the working of valproic acid? Can this combination be taken?
Dulotop 25 does not interfere with the working of valproic acid, but it increases the risk of getting excess levels of ammonia in the blood (hyperammonemia). Increased levels of ammonia in the blood can be dangerous and may cause difficulty in thinking, remembering information, or solving problems. It may also decrease your alertness and make you feel very sleepy with low energy. Immediately inform your doctor if you notice these symptoms. It is important to know that, in rare cases, Dulotop 25 alone can cause hyperammonemia.
Since I have started using Dulotop 25 people are saying that I have lost weight. Is it because of Dulotop 25 or something else for which I should get investigated?
It could be due to Dulotop 25 because Dulotop 25 commonly causes weight loss probably due to a decrease in appetite. If you still have any doubts, talk to your doctor who will advise you appropriately.
For how long do I need to take Dulotop 25?
The dose and duration of this medicine will depend on your doctor’s advice. Dulotop 25 does not cure your condition (seizures/migraine) but prevents them from occurring. So, you may have to keep taking it for months or years depending on improvement in your symptoms and side effects that may occur.
What if you forget to take Dulotop Tablet?
If you miss a dose of Dulotop 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Dulotop 25 Tablet Reviews
Dulotop 25 is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).
Dulotop 25 may be taken with or without food, preferably at the same time, each day. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. Stopping the medication suddenly without talking to your doctor may cause an increased frequency of seizures. Your doctor may advise regular monitoring of serum bicarbonate levels while you are taking this medicine.
Some of the common side effects of this medicine include nausea, taste change, fatigue, diarrhea, weight loss, loss of appetite, and memory impairment. It may also cause vision problems like myopia or glaucoma, so it is important to get your eyesight checked before you start the treatment and regularly thereafter. You may experience dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Please consult your doctor if these side effects bother you or do not go away.
How Dulotop 25 Tablet Works
Dulotop 25 is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
How to Use Dulotop 25 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dulotop 25 may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Dulotop 25 Tablet
- In Lennox–Gastaut syndrome: Lennox-Gastaut syndrome (LGS) is a rare but severe form of epilepsy that usually starts in early childhood. Affected children may experience several different types of seizures. Dulotop 25 helps prevent and control these seizures by decreasing the nerve impulses which cause the seizures.
- In Prevention of Migraine: It is not fully established how Dulotop 25 helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
- In Epilepsy/Seizures: Dulotop 25 is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.
Uses of Dulotop 25 Tablet
- Epilepsy/Seizures
- Lennox–Gastaut syndrome
- Prevention of Migraine
Dulotop 25 Tablet Side Effects
Safety Tips
Liver
CAUTION
Dulotop 25 should be used with caution in patients with liver disease. Dose adjustment of Dulotop 25 may be needed. Please consult your doctor.
Kidney
CAUTION
Dulotop 25 should be used with caution in patients with kidney disease. Dose adjustment of Dulotop 25 may be needed. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Dulotop 25 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Driving
UNSAFE
Dulotop 25 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Breast feeding
CONSULT YOUR DOCTOR
Dulotop 25 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alcohol
UNSAFE
It is unsafe to consume alcohol with Dulotop 25.
Quick Tips
- Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
- Take your medication on time.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
- Practice yoga every day.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Some healthy tips to prevent seizures:Practice yoga every day.Get enough sleep at nighttime.Limit the use of screen time such as mobile/laptop.Take your medication on time.
- Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Dulotop 25. This can reduce the risk of kidney stones.
- Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
- Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
- Limit the use of screen time such as mobile/laptop.
- Monitor your weight during treatment with this medicine as it can cause weight gain.
- Get enough sleep at nighttime.
References
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Topiramate. [Updated 2020 Jan 20].
- Stahl SM, editor. Topiramate. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 669-73.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1380-82.
- Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 12.
- Topiramate. Gurabo, Puerto Rico: Janssen Ortho; 2012.
- Central Drugs Standard Control Organisation (CDSCO).
- McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 601.
- Topiramate. High Wycombe, Bucks: Janssen-Cilag Ltd.; 1995 [revised 13 Dec. 2017].
- Topiramate [Prescribing Information]. 2012. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2009.